Results 61 to 70 of about 11,205,379 (410)

The dual nature of TDC – bridging dendritic and T cells in immunity

open access: yesFEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Function and autophagy of monocyte-derived dendritic cells is affected by hepatitis B virus infection

open access: yesBMC Immunology, 2023
Background The role of dendritic cells and the autophagy state of dendritic cells in the immune response of hepatitis B virus (HBV) infection was still controversial.
Hua Xu   +7 more
doaj   +1 more source

Dendritic Cell and Immune Tolerence [PDF]

open access: yes, 2010
Introduction ot Dendritic Cells: Dendritic cell and immune tolerencehttps://digitalcommons.rockefeller.edu/introduction-dendritic-cells/1000/thumbnail ...
Laboratory, Steinman
core   +1 more source

Direct Inhibition of T-Cell Responses by the Cryptococcus Capsular Polysaccharide Glucuronoxylomannan [PDF]

open access: yes, 2006
The major virulence factor of the pathogenic fungi Cryptococcus neoformans and C. gattii is the capsule. Glucuronoxylomannan (GXM), the major component of the capsule, is a high-molecular-weight polysaccharide that is shed during cryptococcosis and can ...
Lam, Jennifer S   +2 more
core   +4 more sources

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

CD1c-related DCs that express CD207/langerin, but are distinguishable from Langerhans cells, are consistently present in human tonsils

open access: yesFrontiers in Immunology, 2016
Several subsets of dendritic cells (DCs) are present in the oropharyngeal tonsillar tissues and are thought to behave as major actors in development and regulation of immunity by acting as a first line of recognition for airborne and alimentary antigens.
Anne eDe Monte   +13 more
doaj   +1 more source

Discovery [PDF]

open access: yes, 2010
Introduction to Dendritic Cells: Discoveryhttps://digitalcommons.rockefeller.edu/introduction-dendritic-cells/1001/thumbnail ...
Laboratory, Steinman
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Functional identification of dendritic cells in the teleost model, rainbow trout (Oncorhynchus mykiss). [PDF]

open access: yesPLoS ONE, 2012
Dendritic cells are specialized antigen presenting cells that bridge innate and adaptive immunity in mammals. This link between the ancient innate immune system and the more evolutionarily recent adaptive immune system is of particular interest in fish ...
Elizabeth Bassity, Theodore G Clark
doaj   +1 more source

Universal Chemomechanical Design Rules for Solid-Ion Conductors to Prevent Dendrite Formation in Lithium Metal Batteries [PDF]

open access: yesNature Materials, 19, 758-766 (2020), 2019
Dendrite formation during electrodeposition while charging lithium metal batteries compromises their safety. While high shear modulus solid-ion conductors (SICs) have been prioritized to resolve pressure-driven instabilities that lead to dendrite propagation and cell shorting, it is unclear whether these or alternatives are needed to guide uniform ...
arxiv   +1 more source

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