Results 61 to 70 of about 11,507,286 (389)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Introduction to Dendritic Cells [PDF]
, 2010 Introduction to Dendritic Cellshttps://digitalcommons.rockefeller.edu/introduction-dendritic-cells/1003/thumbnail ...
Laboratory, Steinman
core +1 more source
Antigen-Specific Polyclonal Cytotoxic T Lymphocytes Induced by Fusions of Dendritic Cells and Tumor Cells [PDF]
, 2010 The aim of cancer vaccines is induction of tumor-specific cytotoxic T lymphocytes (CTLs) that can reduce the tumor mass. Dendritic cells (DCs) are potent antigen-presenting cells and play a central role in the initiation and regulation of primary immune ...
Gong, Jianlin +6 more
core +5 more sources
Dendritic Cell Differentiation [PDF]
The Journal of Immunology, 2004 Dauer et al. ([1][1]) presented a method to differentiate CD14+ cells into mature dendritic cells (DC) within 48 h (FastDC). FastDC displayed a DC-like morphology, down-regulated CD14, and induced proliferation of autologous T cells against soluble Ags as efficiently as standard monocyte-derived ...
Curti A +4 more
openaire +4 more sources
Dendritic Cells and CD8 T Cell Immunity in Tumor Microenvironment
Frontiers in Immunology, 2018 Dendritic cells (DCs) play a central role in the regulation of the balance between CD8 T cell immunity vs. tolerance to tumor antigens. Cross-priming, a process which DCs activate CD8 T cells by cross-presenting exogenous antigens, plays a critical role ...
Chunmei Fu, Aimin Jiang
semanticscholar +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Dermatologica Sinica, 2017 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy that usually occurs in elderly individuals and manifests with skin lesions followed by involvement of the lymph nodes, bone marrow, and peripheral blood.
Chien-yio Lin +3 more
doaj +1 more source
Dendritic Cell and Immune Tolerence [PDF]
, 2010 Introduction ot Dendritic Cells: Dendritic cell and immune tolerencehttps://digitalcommons.rockefeller.edu/introduction-dendritic-cells/1000/thumbnail ...
Laboratory, Steinman
core +1 more source
MHC Class I+/II− Dendritic Cells Induce Hapten-Specific Immune Responses In Vitro and In Vivo [PDF]
, 1978 Activation requirements and biologic properties of hapten-specific, major histocompatibility complex class I-restricted CD8+ T lymphocytes are not fully understood.
Andrea Kolesaric +25 more
core +1 more source
Current Opinion in Immunology, 2015 Dendritic cells (DCs) are versatile controllers of the immune system, best known for their potent ability to initiate adaptive immunity. Traditionally, DCs have been defined on the basis of cell morphology, expression of specific markers and select functional attributes such as the ability to migrate to T cell areas of secondary lymphoid organs and ...
Barbara U Schraml, Caetano Reis e Sousa
openaire +2 more sources