Results 121 to 130 of about 40,867 (262)

Cancer Treatment and Bone Health [PDF]

, 2018
Considerable advances in oncology over recent decades have led to improved survival, while raising concerns about long-term consequences of anticancer treatments.
A Falahati-Nini, A Garg, A Lipton, A Llombart, A Morishima, A Tomkinson, AM Brufsky, AR Hong, B Buehring, BF Boyce, BL Clarke, BL Clarke, C Christensen, C Magno, C Poznak Van, C Shapiro, C Wilson, Catherine Handforth, CH Kasperk, CJ Stava, D Goldray, D Vanderschueren, DA Cameron, DA Galvão, DL Hershman, DM Huber, DS Perrien, Early Breast Cancer Trialists, EP Smith, F Mazzuca, FA Trémollieres, GK Ellis, HG Bone, HW Daniell, I Fogelman, I Sestak, J Morote, J Pfeilschifter, J Planas, Janet Brown, JD Wilson, JE Lester, JE Lester, JF Forbes, JL Mohler, JM Bruder, KB Emerton, KM Nicks, L Bošković, L Vehmanen, LC Hofbauer, LC Hofbauer, LH Klotz, LP Fried, M Bauer, M Datta, M Gnant, M Gnant, M Kalder, M Kalder, M Rabaglio, MD Michaelson, MG Oefelein, MM Agarwal, MR Smith, MR Smith, MR Smith, MR Smith, MR Smith, MR Smith, N Majithia, N Napoli, ND James, ND Wagner-Johnston, P Hadji, P Hadji, P Hadji, P Hadji, P Rodrigues, PD Miller, PE Goss, PE Goss, PL Nguyen, R Choo, R Coleman, R Coleman, R Eastell, R Eastell, R Soleimani, RA Adler, RE Coleman, RJ Segal, Robert Coleman, S Dhesy-Thind, S D’Oronzo, SL Greenspan, Stella D’Oronzo, SY Ying, T Kameda, T Liu, T Rana, T Saarto, TA Guise, TH Diamond, TJ Powles, V Carnevale, V Subbiah, VB Shahinian, W Vale, WJ Boyle   +109 more
core   +2 more sources

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Bisphosphonate- and disumab-related gingival disorders: case analysis from the U.S. Food and Drug Administration Adverse Event Reporting System

Frontiers in Endocrinology
Prior research has indicated that bisphosphonates (BPs) can improve periodontal disease because of their anti-osteoporosis properties. In vitro studies have shown that BPs induce cytotoxicity, inhibit wound healing, and thus affect periodontal disease ...
Lei Wang, Wei Zhang, Cheng-long Zhao, Zhong-hua Fu   +3 more
doaj   +1 more source

Bone health in adults with non‐ambulatory neuromuscular disorders: scoping review of risk factors, diagnosis and management

Internal Medicine Journal, EarlyView.
Abstract Background Non‐ambulatory adults have an increased risk of osteoporosis and fractures due to reduced weight‐bearing and diminished neuromuscular stimulation, resulting in substantial morbidity and mortality. Aims This scoping review aimed to systematically evaluate risk factors, diagnostic indicators and management strategies for optimising ...
Thomas Bailey, Carolyn Droste, John A. Eisman, Steven G. Faux, Arnagretta Hunter   +4 more
wiley   +1 more source

Recent Developments in Osteogenesis Imperfecta [PDF]

, 2015
Osteogenesis imperfecta (OI) is an uncommon genetic bone disease associated with brittle bones and fractures in children and adults. Although OI is most commonly associated with mutations of the genes for type I collagen, many other genes (some ...
Albert, Carolyne, Fritz, Jessica M., Harris, Gerald F., Shaker, Joseph L.   +3 more
core   +2 more sources

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Case report: A case of ITP-like thrombocytopenia induced by denosumab

Frontiers in Pharmacology
Denosumab has been widely utilized in the management of osteoporosis; however, thrombocytopenia as an adverse reaction associated with denosumab has been infrequently reported, and its underlying mechanism is not yet fully understood.
Shijing Chen, Xiahong Lin
doaj   +1 more source

Severe Hypocalcemia and Hypomagnesemia with Denosumab in Advanced Chronic Kidney Disease: Case Report and Literature Review

Case Reports in Oncological Medicine, 2018
Background. Denosumab has become the preferred agent over zolendronic acid to help prevent skeletal-related events in patients with metastatic bone disease and multiple myeloma because it is approved for use in those with kidney dysfunction.
Christina F. Marlow, Shailendra Sharma, Faizan Babar, Jianqing Lin   +3 more
doaj   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

Oral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier, Tim Hildebrandt, Ina Dewenter, Wenko Smolka, Eric Hesse, Philipp Poxleitner, Sven Otto   +6 more
wiley   +1 more source

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

Oral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem, Gavriel Chaushu, Daya Masri   +2 more
wiley   +1 more source