Results 131 to 140 of about 40,867 (262)

Denosumab cessation [PDF]

Cleveland Clinic Journal of Medicine, 2020
openaire   +2 more sources

Denosumab as Second-Line Treatment in Patients With Metastatic Breast Cancer: A Retrospective Descriptive Pilot Study From a Single Institution

Cancer Control
Introduction Bone metastasis in breast cancer patients can lead to poor quality of life and cause significant morbidity. First-line treatments for bone metastases include bone modifying agents that inhibit osteoclast activity to reduce bone resorption ...
Briana To, Laura E. Wright, Dureti Doto, Julie Stephans, Marilly Palettas, Kai C. Johnson, Mathew Cherian, Daniel Stover, Ashley Davenport, Margaret Gatti-Mays, Robert Wesolowski, Dionisia Quiroga, Sagar Sardesai, Gilbert Bader, Bhuvaneswari Ramaswamy, Nicole Williams   +15 more
doaj   +1 more source

A multicenter case registry study on medication-related osteonecrosis of the jaw in patients with advanced cancer [PDF]

, 2018
PURPOSE: This observational case registry study was designed to describe the natural history of cancer patients with medication-related osteonecrosis of the jaw (ONJ) and evaluate the ONJ resolution rate.
Chambers, MS, Coropciuc, R, Fedele, S, Jandial, D, Ma, H, Nicolatou-Galitis, O, Politis, C, Saunders, DP, Schiodt, M, Vadhan-Raj, S, Zhang, J   +10 more
core  

New molecular targets in bone metastases [PDF]

, 2010
Bone metastases have a major impact on morbidity and on mortality in cancer patients. Despite its clinical relevance, metastasis remains the most poorly elucidated aspect of carcinogenesis.
Colucci, G., Fratto, M., Galluzzo, S., Gucciardino, C., LOMBARDI, LUCIO, Maiello, E., Pantano, F., Riva, E., RIZZO, Sergio, RUSSO, Antonio, SANTINI, Daniele, Silvestris, N., Tonini, G., Vincenzi, B., Zoccoli, A.   +14 more
core   +1 more source

MRONJ Risk Related to Dental Implants in Osteoporosis Treated With Denosumab: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objectives The aim of this systematic review was to assess the impact of dental implants in osteoporotic patients undergoing treatment with denosumab on MRONJ development, considering both implant surgery‐triggered osteonecrosis (ISTO) and implant presence‐triggered osteonecrosis (IPTO).
Rebheca Maria Pereira Santos, Giulia Ottaviani, Roberto Di Lenarda, Matteo Biasotto, Katia Rupel   +4 more
wiley   +1 more source

Structure model index does not measure rods and plates in trabecular bone [PDF]

, 2015
Structure model index (SMI) is widely used to measure rods and plates in trabecular bone. It exploits the change in surface curvature that occurs as a structure varies from spherical (SMI = 4), to cylindrical (SMI = 3) to planar (SMI = 0).
Altman, Arlot, Arlot, Ashby, Bayraktar, Bevill, Borah, Boyd, Buie, Campbell, Campbell, Chappard, Core Team R, Cotter, Day, Doube, Doube, Doube, Doube, Glatt, Halloran, Hildebrand, Hunter, Ito, Jiang, Jobke, Khajuria, Khedgikar, Komatsubara, Laib, Li, Liu, Lorensen, Macrae, Maquer, Mittra, Mittra, Mócsai, Müller, Patsch, Perilli, Perilli, Recker, Reid, Roux, Rubin, Sashidhara, Schmid, Schneider, Shi, Simic, Skedros, Stauber, Teo, Tivesten, Waarsing, Wang, Ward, Wegrzyn, Wei, Yakacki, Zhang   +61 more
core   +3 more sources

Is Fluorescence‐Guided Surgery Reliable for the Treatment of MRONJ? A Systematic Review and Meta‐Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Identification of healthy bone margins is a critical step in the surgical resective treatment of medication‐related osteonecrosis of the jaw (MRONJ). Fluorescence‐guided surgery (FGS) has been proposed as a method to identify resection margins and improve clinical outcomes.
Paolo De Angelis, Alessandro Donato Tescione, Ivan Michele Aniceto, Cosimo Rupe, Gioele Gioco, Romeo Patini, Carlo Lajolo   +6 more
wiley   +1 more source

Follow-Up of Bone Mineral Density Changes in de novo Kidney Transplant Recipients Treated with Two Doses of the Receptor Activator of Nuclear Factor κB Ligand Inhibitor Denosumab

Kidney & Blood Pressure Research, 2019
Background: Studies in women with post-menopausal osteoporosis have shown that discontinuation of treatment with denosumab leads to an increased risk of vertebral fractures because of rebound bone turnover and rapid loss of bone mineral density (BMD ...
Claudia Kobel, Diana Frey, Nicole Graf, Rudolf P. Wüthrich, Marco Bonani   +4 more
doaj   +1 more source

Giant Cell Tumor of Bone: Documented Progression over 4 Years from Its Origin at the Metaphysis to the Articular Surface. [PDF]

, 2016
The exact location of origin for giant cell tumors of bone (GCTB) remains controversial, as lesions are not routinely imaged early but rather late when the tumor is large and clinically symptomatic.
Burke, Colin, Cho, Soo-Jin, Link, Thomas, Motamedi, Daria, O'Donnell, Richard J   +4 more
core   +4 more sources

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source