Development and Comparison of Two Multiresidue Methods for the Determination of 17 Aspergillus and Fusarium Mycotoxins in Cereals Using HPLC-ESI-TQ-MS/MS [PDF]
Cereals can be contaminated by several mycotoxins, whose co-presence may represent an undervalued risk for humans and animals. Maize and wheat are the most contaminated cereals and in temperate areas could be affected in field conditions by several ...
Valentina Scarpino+2 more
doaj +4 more sources
Simultaneous determination of Deoxynivalenol, Deoxynivalenol-3-Glucoside and Nivalenol in wheat grains by HPLC-PDA with immunoaffinity column cleanup [PDF]
Deoxynivalenol-3-glucoside (D3G) is a modified mycotoxin formed by the metabolism of plants through the conjugation of deoxynivalenol (DON) with glucose.
A Dall’Erta+39 more
core +2 more sources
Metabolism of the masked mycotoxin deoxynivalenol-3-glucoside in rats.
Nagl V+7 more
europepmc +3 more sources
Recent reports have demonstrated that the deoxynivalenol (DON) mycotoxin produced by Fusarium sp. is metabolized to deoxynivalenol-3-glucoside (DON-3G) by glycosidation enzymes in infected plants, and subsequently DON-3G accumulates in the plant body ...
Miho Kawanishi+2 more
openalex +3 more sources
Chemical Synthesis of Deoxynivalenol-3-β-d-[13C6]-glucoside and Application in Stable Isotope Dilution Assays [PDF]
Modified mycotoxins have been gaining importance in recent years and present a certain challenge in LC-MS/MS analysis. Due to the previous lack of a labeled isotopologue of the modified mycotoxin deoxynivalenol-3-glucoside, in our study we synthesized ...
Katharina Habler+2 more
doaj +2 more sources
In vivo contribution of deoxynivalenol-3-β-D-glucoside to deoxynivalenol exposure in broiler chickens and pigs: oral bioavailability, hydrolysis and toxicokinetics [PDF]
Crossover animal trials were performed with intravenous and oral administration of deoxynivalenol-3-β-D-glucoside (DON3G) and deoxynivalenol (DON) to broiler chickens and pigs. Systemic plasma concentrations of DON, DON3G and de-epoxy-DON were quantified
Adam, Gerhard+12 more
core +2 more sources
Plant-Derived UDP-Glycosyltransferases for Glycosylation-Mediated Detoxification of Deoxynivalenol: Enzyme Discovery, Characterization, and In Vivo Resistance Assessment. [PDF]
Fungal infections of crops pose a threat to global agriculture. Fungi of the genus Fusarium cause widespread diseases in cereal crops. Fusarium graminearum reduces yields and produces harmful mycotoxins such as deoxynivalenol (DON).
Della Gala V+6 more
europepmc +2 more sources
A Multi-Year Study of Mycotoxin Co-Occurrence in Wheat and Corn Grown in Ontario, Canada. [PDF]
Mycotoxin emergence and co-occurrence trends in Canadian grains are dynamic and evolving in response to changing weather patterns within each growing season.
Kelman MJ+4 more
europepmc +2 more sources
Impact of Environmental Conditions on the Concentrations of Trichothecenes, Their Glucosides, and Emerging <i>Fusarium</i> Toxins in Naturally Contaminated, Irradiated, and <i>Fusarium langsethiae</i> Inoculated Oats. [PDF]
Trichothecenes produced by Fusarium species are commonly detected in oats. However, the ratios of the concentrations of free trichothecenes and their conjugates and how they are impacted by different interacting environmental conditions are not well ...
Oluwakayode A+5 more
europepmc +2 more sources
Biochemical Characterization of a Recombinant UDP-glucosyltransferase from Rice and Enzymatic Production of Deoxynivalenol-3-O-β-D-glucoside [PDF]
Glycosylation is an important plant defense mechanism and conjugates of Fusarium mycotoxins often co-occur with their parent compounds in cereal-based food and feed.
Herbert Michlmayr+8 more
doaj +2 more sources