Results 81 to 90 of about 2,794 (185)

Investigating GERMs: how genotype, environment, and rhizosphere microbiome interactions underlie heat response in maize and sorghum

New Phytologist, EarlyView.
Three genotypes – a heat‐resistant maize (Zea mays), a heat‐susceptible maize, and a sorghum (Sorghum bicolor) variety – were grown to the V4 stage in growth chambers under optimal conditions or subjected to heat stress. Plants were grown in soil containing a complex microbial community, or in the same soil with a depleted microbiome.
Nate Korth, Isabella Borrero, Katelyn Rumley, Alex L. Woodley, Mallory J. Choudoir, Joseph L. Gage   +5 more
wiley   +1 more source

The malleable brain: plasticity of neural circuits and behavior: A review from students to students [PDF]

, 2017
One of the most intriguing features of the brain is its ability to be malleable, allowing it to adapt continually to changes in the environment. Specific neuronal activity patterns drive long-lasting increases or decreases in the strength of synaptic ...
Adeniyi, Philip A., Ali, Nilufar, Amini, Elham, Blumrich, Eva Maria, Datusalia, Ashok K., Fontanet, Paula, García Romero, Ezra Michelet, Ghosh, Shampa, Golpich, Mojtaba, Hegemann, Regina U., Jain, Vishal, Jamwal, Sumit, Joshi, Pooja, Kushwah, Neetu, Lepeta, Katarzyna, Loke, Hannah, Lourenco, Mychael V., Nawrotek, Katarzyna, Paid, Ramesh K., Pastor, Verónica, Piermartiri, Tetsade, Rotermund, Carola, Saini, Vedangana, Salamian, Ahmad, Schaefer, Natascha, Shahidzadeh, Sheila M., Sharma, Mahima, Sharma, Sorabh, Sinha, Jitendra K., Suárez Pozos, Edna, Turner, Anthony J., Vafadari, Benham, Wilson, Yvette   +32 more
core   +2 more sources

Protein Palmitoylation Modification During Viral Infection and Detection Methods of Palmitoylated Proteins

Frontiers in Cellular and Infection Microbiology, 2022
Protein palmitoylation—a lipid modification in which one or more cysteine thiols on a substrate protein are modified to form a thioester with a palmitoyl group—is a significant post-translational biological process. This process regulates the trafficking,
Xiaoling Li, Lingyi Shen, Zhao Xu, Wei Liu, Aihua Li, Jun Xu   +5 more
doaj   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Palmitoylation and Membrane Association of the Stress Axis Regulated Insert (STREX) Controls BK Channel Regulation by Protein Kinase C [PDF]

, 2012
Large-conductance, calcium- and voltage-gated potassium (BK) channels play an important role in cellular excitability by controlling membrane potential and calcium influx.
Barman, Bell, Benkusky, Butler, Chen, El Husseini, Ferrer, Fukao, Fukata, Hall, Hamill, Holdiman, Jennings, Kundu, Lagrutta, Lai, Lin, Lovell, Mahmoud, Mahmoud, Meredith, Orio, Pickering, Quirk, Ruth, Rüttiger, Saito, Sausbier, Sausbier, Schubert, Schubert, Shipston, Shipston, Shipston, Tian, Tian, Tian, Tseng-Crank, Werner, White, Xie, Zhou, Zhou, Zhou, Zhu   +44 more
core   +1 more source

Substrate selectivity in the zDHHC family of S-acyltransferases [PDF]

, 2017
S-acylation is a reversible lipid modification occurring on cysteine residues mediated by a family of membrane-bound 'zDHHC' enzymes. S-acylation predominantly results in anchoring of soluble proteins to membrane compartments or in the trafficking of ...
Chamberlain, Luke H., Diez-Ardanuy, Cinta, Greaves, Jennifer, Kouskou, Marianna, Lemonidis, Kimon, Salaun, Christine   +5 more
core   +1 more source

Akap5 links synaptic dysfunction to neuroinflammatory signaling in a mouse model of infantile neuronal ceroid lipofuscinosis

Frontiers in Synaptic Neuroscience
Palmitoylation and depalmitoylation represent dichotomic processes by which a labile posttranslational lipid modification regulates protein trafficking and degradation.
Kevin P. Koster, Zach Fyke, Thu T. A. Nguyen, Amanda Niqula, Lorena Y. Noriega-González, Kevin M. Woolfrey, Mark L. Dell’Acqua, Stephanie M. Cologna, Akira Yoshii, Akira Yoshii, Akira Yoshii   +10 more
doaj   +1 more source

Subcellular localisation of FLAG tagged enzymes of the dynamic protein S-palmitoylation cycle of Trypanosoma cruzi epimastigotes

Memorias do Instituto Oswaldo Cruz, 2018
Dynamic S-palmitoylation of proteins is the addition of palmitic acid by zDHHC palmitoyl transferases (PATs) and depalmitoylation by palmitoyl protein thioesterases (PPTs).
Cassiano Martin Batista, Felipe Saad, Stephane Pini Costa Ceccoti, Iriane Eger, Maurilio José Soares   +4 more
doaj   +1 more source

An Amphipathic α-Helix Directs Palmitoylation of the Large Intracellular Loop of the Sodium/Calcium Exchanger [PDF]

, 2017
The electrogenic sodium/calcium exchanger (NCX) mediates bidirectional calcium transport controlled by the transmembrane sodium gradient. NCX inactivation occurs in the absence of phosphatidylinositol 4,5-bisphosphate and is facilitated by palmitoylation
Blanc, Chaptal, Drozdetskiy, Fukata, Fuller, Giladi, Hilge, Hilgemann, Howie, John, Kumari, Lemonidis, Lemonidis, Li, Liao, Linder, Lytton, Maack, Matsuoka, Matsuoka, Nadolski, Nicoll, Ottolia, Philipson, Reddy, Reilly, Reményi, Ren, Ren, Rocks, Shipston, Thomas   +31 more
core   +3 more sources

Palmitoylation is required for TNF-R1 signaling

Cell Communication and Signaling, 2019
Background Binding of tumor necrosis factor (TNF) to TNF-receptor 1 (TNF-R1) can induce either cell survival or cell death. The selection between these diametrically opposed effects depends on the subcellular location of TNF-R1: plasma membrane retention
Philipp Zingler, Vinzenz Särchen, Timo Glatter, Lotta Caning, Carina Saggau, Rahul S. Kathayat, Bryan C. Dickinson, Dieter Adam, Wulf Schneider-Brachert, Stefan Schütze, Jürgen Fritsch   +10 more
doaj   +1 more source