Results 1 to 10 of about 2,208 (133)

Lichen-Derived Diffractaic Acid Inhibited Dengue Virus Replication in a Cell-Based System [PDF]

Molecules, 2023
Dengue is a mosquito-borne flavivirus that causes 21,000 deaths annually. Depsides and depsidones of lichens have previously been reported to be antimicrobials. In this study, our objective was to identify lichen-derived depsides and depsidones as dengue
Naphat Loeanurit, Truong Lam Tuong, Van-Kieu Nguyen, Vipanee Vibulakhaophan, Kowit Hengphasatporn, Yasuteru Shigeta, Si Xian Ho, Justin Jang Hann Chu, Thanyada Rungrotmongkol, Warinthorn Chavasiri, Siwaporn Boonyasuppayakorn   +10 more
doaj   +2 more sources

Genome Mining-Guided Discovery of Two New Depsides from Talaromyces sp. HDN1820200 [PDF]

Marine Drugs
Depsides and their derivatives are a class of polyketides predominantly found in fungal extracts. Herein, a silent nonreducing polyketide synthase (TalsA)-containing gene cluster, which was identified from the Antarctic sponge-derived fungus Talaromyces ...
Xiao Zhang, Luyang Liu, Jiani Huang, Xingtao Ren, Guojian Zhang, Qian Che, Dehai Li, Tianjiao Zhu   +7 more
doaj   +2 more sources

It Is Not All about Alkaloids—Overlooked Secondary Constituents in Roots and Rhizomes of Gelsemium sempervirens (L.) J.St.-Hil [PDF]

Plants
Gelsemium sempervirens (L.) J.St.-Hil. is an evergreen shrub occurring naturally in North and Middle America. So far, more than 120 alkaloids have been identified in this plant in addition to steroids, coumarins and iridoids, and its use in traditional ...
Lilo K. Mailänder, Khadijeh Nosrati Gazafroudi, Peter Lorenz, Rolf Daniels, Florian C. Stintzing, Dietmar R. Kammerer   +5 more
doaj   +2 more sources

Biosynthetic gene cluster synteny: Orthologous polyketide synthases in Hypogymnia physodes, Hypogymnia tubulosa, and Parmelia sulcata [PDF]

MicrobiologyOpen, 2023
Lichens are symbiotic associations consisting of a photobiont (algae or cyanobacteria) and a mycobiont (fungus), which together generate a variety of unique secondary metabolites.
Nadim Ahmad, Manfred Ritz, Anjuli Calchera, Jürgen Otte, Imke Schmitt, Thomas Brueck, Norbert Mehlmer   +6 more
doaj   +2 more sources

The isolation, analytical characterization by HPLC-UV and NMR spectroscopy, cytotoxic and antioxidant activities of baeomycesic acid from Thamnolia vermicularis var. subuliformis [PDF]

Hemijska Industrija, 2011
The aim of this work was the analytical characterization of the β-orcinol depside, baeomycesic acid in lichens extracts. The extract of Thamnolia vermicularis var.
Manojlović Nedeljko T., Vasiljević Perica J., Nikolić Dragan, Bogdanović-Dušanović Gordana, Marković Zoran S., Najman Stevo   +5 more
doaj   +3 more sources

Identification of Secondary Metabolites from the Lichen Hypotrachyna enderythraea (Zahlbr.) Hale by HPLC-ESI-MS/MS [PDF]

Molecules
In this study, sixteen secondary metabolites, including two chromones, four dibenzofurans, three lipids, three depsides, two aromatic compounds, a quinone, and a terpene, were detected in the methanol:acetone (1:1 v/v) extract of the lichen Hypotrachyna ...
Fernando Carrasco, Wilfredo Hernández, Nino Castro, Nelly Sivipaucar, Bruno Bongiorno, Oscar Chupayo, Cesar Raposo, Lúcia A. Silva, Jesus M. Rodilla, Eduardo Carrasco, Juan Z. Dávalos   +10 more
doaj   +2 more sources

Rosarugosides A and D from Rosa rugosa Flower Buds: Their Potential Anti-Skin-Aging Effects in TNF-α-Induced Human Dermal Fibroblasts [PDF]

Plants
This present study investigated the anti-skin-aging properties of Rosa rugosa. Initially, phenolic compounds were isolated from a hot water extract of Rosa rugosa’s flower buds. Through repeated chromatography (column chromatography, MPLC, and prep HPLC),
Kang Sub Kim, So-Ri Son, Yea Jung Choi, Yejin Kim, Si-Young Ahn, Dae Sik Jang, Sullim Lee   +6 more
doaj   +2 more sources

Efficient Production of Some Bioactive Depsides and Simple Phenolic Acids by Microshoots of Aronia × Prunifolia (Purple Aronia) Agitated Cultures as the Result of Feeding Strategy with Four Different Biogenetic Precursors [PDF]

Molecules
A precursor feeding strategy was used for the first time in agitated microshoot cultures of Aronia × prunifolia. This strategy involved the addition of biogenetic precursors of simple phenolic acids (phenylalanine, cinnamic acid, and benzoic acid) and ...
Paweł Kubica, Agnieszka Szopa, Adam Setkiewicz, Halina Ekiert   +3 more
doaj   +2 more sources

Unveiling the therapeutic potential of Lobaria extract and its depsides/depsidones in combatting Aβ42 peptides aggregation and neurotoxicity in Alzheimer’s disease [PDF]

Frontiers in Pharmacology
Background: The development of effective inhibitors that can inhibit amyloid β (Aβ) peptides aggregation and promote neurite outgrowth is crucial for the possible treatment of Alzheimer’s disease (AD).
Meixia Yang, Meixia Yang, Caishan Yan, Dusadee Ospondpant, Dusadee Ospondpant, Lisong Wang, Shengying Lin, Shengying Lin, Wai Lun Tang, Wai Lun Tang, Tina Tingxia Dong, Tina Tingxia Dong, Penger Tong, Qin Xu, Karl Wah Keung Tsim, Karl Wah Keung Tsim   +15 more
doaj   +2 more sources

Lichen Depsides and Tridepsides: Progress in Pharmacological Approaches

Journal of Fungi, 2023
Depsides and tridepsides are secondary metabolites found in lichens. In the last 10 years, there has been a growing interest in the pharmacological activity of these compounds.
Isabel Ureña-Vacas, Elena González-Burgos, Pradeep Kumar Divakar, María Pilar Gómez-Serranillos   +3 more
doaj   +1 more source