Synthesis and biological application of depsipeptides
, 2019 Peptidi čine skupinu spojeva koji se zbog određenih nepovoljnih farmakoloških i biomedicinskih karakteristika, ne mogu koristiti u terapeutske svrhe.
Vlahov, Josipa
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Acyl depsipeptide (ADEP) resistance in Streptomyces
Microbiology, 2011 ADEP, a molecule of the acyl depsipeptide family, has an antibiotic activity with a unique mode of action. ADEP binding to the ubiquitous protease ClpP alters the structure of the enzyme. Access of protein to the ClpP proteolytic chamber is therefore facilitated and its cohort regulatory ATPases (ClpA, ClpC, ClpX) are not required.
Myriam, Gominet +2 more
openaire +2 more sources
Cyclic Carbo-Isosteric Depsipeptides and Peptides as a Novel Class of Peptidomimetic
, 2014 A novel and highly efficient cyclization method has been developed to access a new class of cyclic carbo-isosteric depsipeptides and peptides as drug-like molecules.
Roth, Hans-Joerg +2 more
core +1 more source
Total Syntheses and Configuration Assignments of JBIR-06 and Related Depsipeptides
, 2019 The first total syntheses of JBIR-06 and two analogous depsipeptides, 12-membered antimycin-class antibiotics, have been accomplished via Shiina macrolactonization. Comparison of the spectroscopic data of the synthesized compounds with those reported for
Hikaru Ogawa (6276827) +5 more
core +1 more source
Marine Drugs, 2017 Bioassay-guided isolation of the lipophilic extract of Trichodesmium thiebautii bloom material led to the purification and structure characterization of two new hybrid polyketide-non-ribosomal peptide (PKS-NRPS) macrocyclic compounds, tricholides A and B
Matthew J. Bertin +7 more
doaj +1 more source
Cavomycins A–C, Linear Oligomer Depsipeptides from an Annelid-Associated Streptomyces cavourensis
Three unique linear oligomeric depsipeptides, designated as cavomycins A–C (1–3), were identified from Streptomyces cavourensis, a gut bacterium associated with the annelid Paraleonnates uschakovi.
Scott Franzblau (2272048) +19 more
core +1 more source
The development of depsipeptides as tissue engineering scaffolds : synthesis, characterization, and self-assembly into hydrogels [PDF]
, 2014 textThe development of novel, peptide based structures for tissue engineering materials has been widely researched, and its popularity can be attributed to advancements in technological analysis methods.
Nguyen, Mary Minh Chau
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Cyclic Carbo-Isosteric Depsipeptides and Peptides as a Novel Class of Peptidomimetics
, 2016 A novel and highly efficient cyclization method has been developed to access a new class of cyclic carbo-isosteric depsipeptides and carbo-isosteric peptides.
Hans-Jörg Roth (1508320) +2 more
core +1 more source
Dudawalamides A−D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens [PDF]
, 2017 HPLC. DudA family of 2,2-dimethyl-3-hydroxy-7-octynoic acid (Dhoya)-containing cyclic depsipeptides, named dudawalamides A−D (1−4), was isolated from a Papua New Guinean field collection of the cyanobacterium Moorea producens using bioassay-guided and ...
Gerwick, William H. +11 more
core +1 more source
Ionophoric Activity of Cyclic Depsipeptides from Beauveria bassiana
, 2022 Beauvericin and bassianolide are cyclodepsipeptides produced as secondary metabolites by the fungus Beauveria bassiana. Depsipeptides are molecules of high interest, since some of them show high potential for pharmaceutical applications.
Theuerkauf, Marie
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