Results 81 to 90 of about 5,584 (214)
, 2014 Citation: 'depsipeptides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01604 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
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Acyl depsipeptide (ADEP) resistance in Streptomyces
Microbiology, 2011 ADEP, a molecule of the acyl depsipeptide family, has an antibiotic activity with a unique mode of action. ADEP binding to the ubiquitous protease ClpP alters the structure of the enzyme. Access of protein to the ClpP proteolytic chamber is therefore facilitated and its cohort regulatory ATPases (ClpA, ClpC, ClpX) are not required.
Myriam, Gominet +2 more
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Recent progress in the discovery of macrocyclic compounds as potential anti-infective therapeutics [PDF]
, 2009 Novel therapeutic strategies are urgently needed for the treatment of serious diseases caused by viral, bacterial and parasitic infections, because currently used drugs are facing the problem of rapidly emerging resistance.
Bernardini, F +6 more
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MedComm, Volume 7, Issue 3, March 2026.Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia +4 more
wiley +1 more source
Activating hidden signals by mimicking cryptic sites in a synthetic extracellular matrix
Nature Communications, 2023 Cryptic sites are short signaling peptides buried within the native extracellular matrix (ECM). Enzymatic cleavage of an ECM protein reveals these hidden peptide sequences, which interact with surface receptors to control cell behavior.
Yumeng Zhu +5 more
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Spore Surface Depsipeptides in Some Pithomyces Species [PDF]
Journal of General Microbiology, 1965 SUMMARY: Spicules morphologically similar to those present on the spores of Pithomyces chartarum invest the spores of several other Pithomyces species. Depsipeptides are quantitatively removed from dried mycelial felts by brief chloroform washing, and their amount is proportional to the number of spores present. Three pure spore-coat depsipeptides have
E, BISHOP +4 more
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Pharmaceutical Potential of Marine Organisms [PDF]
, 1998 The use of extracts of plants and animals for medicinal purposes is a practice as old as the history of mankind. However, man's efforts have largely been confined to land plants and animals probably because of their easy accessibility.
Qasim, S Z
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Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides
Journal of Peptide Science, Volume 32, Issue 3, March 2026.As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama +2 more
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Production of the Monamycins, Novel Depsipeptide Antibiotics [PDF]
Applied Microbiology, 1970 Methods are described for the production of the monamycins by Streptomyces jamaicensis in shake flasks and jar fermentors. The effects on the fermentation of variations in p H, temperature, medium composition, volume of inoculum, and strain of the organism are discussed.
M J, Hall, C H, Hassall
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Prva potpuna sinteza i biološko vrednovanje himenamida E [PDF]
, 2006 A new potent bioactive, proline-rich cyclic heptapeptide hymenamide E (13) was synthesized using the solution phase technique by cyclization of the linear peptide Boc-Phe-Pro-Thr-Thr-Pro-Tyr-Phe-OMe (12) after proper deprotection at carboxyl and amino ...
DEVENDER PATHAK +3 more
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