Results 81 to 90 of about 3,874 (203)
Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A
Angewandte Chemie, Volume 138, Issue 26, 22 June 2026.Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham +11 more
wiley +1 more source
Biologically active cyclic depsipeptides from marine cyanobacteria [PDF]
This thesis describes the chemical investigation of marine cyanobacteria collected in Madagascar and Panama with an emphasis on the isolation and structure elucidation of medicinally relevant secondary metabolites.
Medina, Rebecca A.
core +5 more sources
Marine Drugs, 2009 Investigation of an extract from the marine cyanobacterium Lyngbya semiplena, collected in Tumon Bay, Guam, led to the identification of three new cyclodepsipeptides, lyngbyastatins 8–10 (1–3).
Hendrik Luesch +3 more
doaj +1 more source
Cyclodepsipeptides from Marine Sponges: Natural Agents for Drug Research
Marine Drugs, 2010 A number of natural products from marine sponges, such as cyclodepsipeptides, have been identified. The structural characteristics of this family of cyclic peptides include various unusual amino acid residues and unique N-terminal polyketide-derived ...
Rosa Lemmens-Gruber +1 more
doaj +1 more source
Macrocyclic Peptides: Chemistry and Biology of Stapled and Depsipeptides
, 2023 Macrocyclic peptides have been identified as key backbones in several biologically active compounds. They have been considered as great inspiration in the development of novel cyclic scaffolds in medicinal chemistry, notably in the introduction of α ...
Paquette, André
core +1 more source
, 2002 By a chemo-enzymatic approach we performed a large-scale, stereoselective synthesis of the Cα-methylated α-hydroxy acid L-(αMe)Hyv. We also prepared model depsipeptides based on this sterically demanding residue in combination with the α-amino acids L ...
BROXTERMAN Q. B. +10 more
core +1 more source
Preparation and conformational analysis of enantiomeric ferrocene depsipeptides with phenylalanine
Iako sudjeluju u izrazito važnim fiziološkim mehanizmima i kontroliraju gotovo sve vitalne funkcije u organizmu, peptidi nisu pogodi za primjenu u terapeutske svrhe, pa se različitim peptidomimetičkim modifikacijama nastoji prevladati njihova postojeća ...
Vučičević, Vita
core +2 more sources
The development of depsipeptides as tissue engineering scaffolds : synthesis, characterization, and self-assembly into hydrogels [PDF]
, 2014 textThe development of novel, peptide based structures for tissue engineering materials has been widely researched, and its popularity can be attributed to advancements in technological analysis methods.
Nguyen, Mary Minh Chau
core +1 more source
Cavomycins A−C, Linear Oligomer Depsipeptides from an Annelid-Associated Streptomyces cavourensis
Three unique linear oligomeric depsipeptides, designated as cavomycins A−C (1−3), were identified from Streptomyces cavourensis, a gut bacterium associated with the annelid Paraleonnates uschakovi.
Park, Kyu-Hyung +19 more
core +2 more sources
, 2002 By a chemo-enzymatic approach we performed a large-scale, stereoselective synthesis of the Cα-methylated α-hydroxy acid L-(αMe)Hyv. We also prepared model depsipeptides based on this sterically demanding residue in combination with the α-amino acids L ...
Formaggio F. +10 more
core +1 more source