Results 71 to 80 of about 2,854 (178)

Tricholides A and B and Unnarmicin D: New Hybrid PKS-NRPS Macrocycles Isolated from an Environmental Collection of Trichodesmium thiebautii

Marine Drugs, 2017
Bioassay-guided isolation of the lipophilic extract of Trichodesmium thiebautii bloom material led to the purification and structure characterization of two new hybrid polyketide-non-ribosomal peptide (PKS-NRPS) macrocyclic compounds, tricholides A and B
Matthew J. Bertin, Alexandre F. Roduit, Jiadong Sun, Gabriella E. Alves, Christopher W. Via, Miguel A. Gonzalez, Paul V. Zimba, Peter D. R. Moeller   +7 more
doaj   +1 more source

Cryptophycin unit B analogues

Beilstein Journal of Organic Chemistry
Drug conjugates using toxic payloads are a promising approach for selectively combating cancer while sparing healthy tissue. The lack of highly cytotoxic and at the same time selective therapeutics against cancer is an ongoing challenge.
Thomas Schachtsiek, Jona Voss, Maren Hamsen, Beate Neumann, Hans-Georg Stammler, Norbert Sewald   +5 more
doaj   +1 more source

Depsipeptide Analogues of Gly-Ala-Gly: Proton Localization and Effects on Collision-Induced Dissociation. [PDF]

J Am Soc Mass Spectrom
Shira BA, Herndon EC, DeMauro JE, Giuliano MW, Forsythe JG.   +4 more
europepmc   +1 more source

Geodiamolide A, a Marine Sponge Depsipeptide, Halts Proliferation and Triggers Cell Death in Squamous Cell Carcinoma (A431, NMSC) In Vitro. [PDF]

Int J Mol Sci
Rangel M, Ombredane AS, Azevedo RB, Fontes W, Joanitti GA, Castro MS.   +5 more
europepmc   +1 more source

Drug repurposing of natural depsipeptide from <i>Eleftheria terrae</i> isolated via iChip for anti-breast cancer therapy. [PDF]

Front Pharmacol
Fhatonah N, Rustandi T, Abdelmohsen UR, Rasydy OA, Ma'sum, Elghanam Y, Pashar I, Nordin, Mahal A, Riski A.   +9 more
europepmc   +1 more source

Protopeptide backbone affects assembly in aqueous solutions. [PDF]

Proc Natl Acad Sci U S A
Fisher S, Ezerzer Y, Edri R, Akulenko D, Marland E, Frenkel-Pinter M.   +5 more
europepmc   +1 more source

Two New Pentadepsipeptides from the Mangrove Fungus <i>Aspergillus</i> sp. SCSIO 41443. [PDF]

Metabolites
Liu Y, Chen Y, Xiao J, Sun X, Zhou X, Liu Y, Yang B.   +6 more
europepmc   +1 more source

Hypoxia-selective targeting of eEF1A1: A promising therapeutic strategy for triple-negative breast cancer. [PDF]

Acta Pharm Sin B
Liang SH.
europepmc   +1 more source

Biological Evaluation and Potential Applications of Secondary Metabolites from Fungi Belonging to the Cordycipitaceae Family with a Focus on <i>Parengyodontium</i> spp. [PDF]

J Fungi (Basel)
Marin D, Petit P, Pruneau L.
europepmc   +1 more source

Harnessing P^V-oxirene for the modular synthesis of α-Oxy carbonyls. [PDF]

Nat Commun
Huang S, Duan D, Luo J, Chen J, Wang Z.
europepmc   +1 more source