Results 71 to 80 of about 5,584 (214)

Cyclic Peptide Conformational Landscapes Through the Lens of Mass Spectrometry and Orthogonal Spectroscopy

Journal of Mass Spectrometry, Volume 61, Issue 5, May 2026.
ABSTRACT Cyclic peptides occupy a structurally dynamic region of chemical space, where function often arises from ensembles rather than a single dominant fold. Closed backbones, frequent N‐methylation, heteroatoms, unnatural amino acids, and a strong propensity for metal coordination create dense conformational and coordination landscapes that ...
Emmanuel Nkyaagye, Happy Abena Safoah, Thanh D. Do   +2 more
wiley   +1 more source

A contribution to the nomenclature of depsipeptides [PDF]

Journal of Peptide Science, 2003
AbstractDepsipeptides, also called peptolides, are a class of peptidic compounds in which an amide bond has been replaced with an ester bond. The literature does not clearly display rules for the nomenclature of such compounds. Here a method is proposed to transcribe drawn depsipeptide structures in one‐line text.
Sorin V, Filip, Florine, Cavelier
openaire   +2 more sources

Biomedical and therapeutic applications of biosurfactants [PDF]

, 2010
During the last years, several applications of biosurfactants with medical purposes have been reported. Biosurfactants are considered relevant molecules for applications in combating many diseases and as therapeutic agents due to their antibacterial ...
A. Bernheimer, A. Fiechter, A. Flasz, A. Singh, A.B. Moldes, A.L. Moyne, B. Angelova, B. Gan, C. Carrillo, C. Delden Van, C. Heinemann, C.G. Hoogmoed Van, C.L. Wang, C.N. Mulligan, D. Kitamoto, D. Kitamoto, D. Vollenbroich, D. Vollenbroich, D.J. Bidel, D.R. Mack, F. Ahimou, F. Besson, F. Ramisse, G. Reid, G. Reid, G. Reid, G. Reid, G. Reid, H. Isoda, H. Isoda, H. Itokawa, H. Sano, H.J. Busscher, H.J. Busscher, H.J. Busscher, I. Grangemard, I.M. Banat, I.M. Banat, I.M. Banat, I.N.A. Bogaert Van, J. Gerard, J. Im, J.D. Desai, J.D. Hamme Van, J.D. Sheppard, J.H. Im, J.R. Mireles, J.R. Wright, K. Das, K. Das, K. Jenny, K. Kim, K. Millsap, K. Mittenbuhler, L. Thimon, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, L.R. Rodrigues, M. Benincasa, M. Konishi, M. Morikawa, M. Shibahara, M. Velraeds, M. Velraeds, M. Velraeds, M. Velraeds, M. Yakimov, N. G. Dehghan, N. Kosaric, N. Kosaric, N. Naruse, O.M.P. Rivera, P. Gotek, P. Singh, R. Maier, R. Makkar, R. Sen, R.M. Maier, R.T. Otto, S. Boris, S. Cameotra, S. Cameotra, S. Igarashi, S. Ito, S. Joshi, S. Lang, S. Lin, S. Lin, S. Mukherjee, T. I. Pratt, T. Kikuchi, T. Kikuchi, T. Neu, T. Nielsen, T. Sudo, V. Shah, X. Zhao, X. Zhao, Y. Inoh, Y. Inoh, Y. Ishigami, Y. Kameda, Y. Maitani, Y. Tanaka, Y. Uchida, Y. Uchida, Y. Ueno, Y. Ueno, Y. Wakamatsu   +114 more
core   +1 more source

Synthesis of a Carbon‐Linked Acyldepsipeptide Derivative

European Journal of Organic Chemistry, Volume 29, Issue 15, 22 April 2026.
The synthesis of a methylene‐linked acyldepsipeptide (ADEP) is reported. Success relied upon an improve method to generate a versatile vinyl glycine methyl ester synthon and a rationally optimized Grubb’s metathesis. NMR and in silico studies revealed an unusual trans–trans proline orientation for this new unnatural ADEP analog, advancing the ...
Katelyn G. Stevens-Davis, Xiaozheng Dou, Bo Hu, Yangxiong Li, Jiayuan Miao, Yu-Shan Lin, Adam S. Duerfeldt   +6 more
wiley   +1 more source

Chemical Ecology of Streptomyces albidoflavus Strain A10 Associated with Carpenter Ant Camponotus vagus

Microorganisms, 2020
Antibiotics produced by symbiotic microorganisms were previously shown to be of crucial importance for ecological communities, including ants. Previous works on ant–actinobacteria symbiosis are mainly focused on farming ants, which use antifungal ...
Anna A. Baranova, Alexey A. Chistov, Anton P. Tyurin, Igor A. Prokhorenko, Vladimir A. Korshun, Mikhail V. Biryukov, Vera A. Alferova, Yuliya V. Zakalyukina   +7 more
doaj   +1 more source

ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A [PDF]

, 2018
Our understanding of autophagy and lysosomal function has been greatly enhanced by the discovery of natural product structures that can serve as chemical probes to reveal new patterns of signal transduction in cells.
Ian Ganley, Ian Humphreys, Jane Ishmael, Jeffrey Serrill, Kerry McPhail, Li, Michelle Tan, Xuemei Wan, Yoshimori, Zhang   +9 more
core   +3 more sources

Prebiotic Organic Chemistry of Diketopiperazines

Asian Journal of Organic Chemistry, Volume 15, Issue 4, April 2026.
Diketopiperazines (DKPs) are considered essential in many life forms, but their prebiotic importance has not been fully understood. This review aims to discuss prebiotic organic chemistry for experimentally and computationally simulated reactions involving DKPs. ABSTRACT Even though the significance of amino acids and polypeptides is well recognized in
Jun Ohata
wiley   +1 more source

Biochemical Studies of the Lagunamides, Potent Cytotoxic Cyclic Depsipeptides from the Marine Cyanobacterium <em>Lyngbya majuscula</em>

Marine Drugs, 2012
Lagunamides A (<strong>1</strong>) and B (<strong>2</strong>) are potent cytotoxic cyclic depsipeptides isolated from the filamentous marine cyanobacterium, <em>Lyngbya majuscula</em>, from Pulau Hantu, Singapore ...
David Tai Leong, Lik Tong Tan, Ashootosh Tripathi, Wanru Fang   +3 more
doaj   +1 more source

Solonamide B Inhibits Quorum Sensing and Reduces Staphylococcus aureus Mediated Killing of Human Neutrophils [PDF]

, 2014
Methicillin-resistant Staphylococcus aureus (MRSA) continues to be a serious human pathogen, and particularly the spread of community associated (CA)-MRSA strains such as USA300 is a concern, as these strains can cause severe infections in otherwise ...
A Nielsen, AE Clatworthy, AI Hidron, Anita Nielsen, AW Bernheimer, B Amulic, BA Diep, BC Herold, BE Ragle, DA Rasko, Dorte Frees, E Geisinger, EA George, FD Lowy, FD Lowy, G Ji, G Ji, G Sakoulas, G Werner, GJ Lyon, GJ Lyon, GJ Moran, GL Archer, Gunnar F. Kaufmann, GW Krucke, GY Cheung, Hanne Frøkiær, Hanne Ingmer, J Bubeck Wardenburg, JA Loughman, L Cegelski, L Jelsbak, Lone Gram, M Hentzer, M Mansson, M Otto, M Shoham, Maria Månsson, Martin S. Bojer, N Firon, P Mayville, P Recsei, PF Chan, R Wang, Richard P. Novick, RL Thompson, RO Jensen, RP Novick, RP Novick, RP Novick, S Bhakdi, S Bhakdi, S Deresinski, S Jarraud, SF Graves, SV Kazakova, SY Queck, Thomas O. Larsen, TM Jarry, WC Chan   +59 more
core   +2 more sources

Synthesis of Peptides, Peptide Nucleic Acid Components, and Other Biogenic Compounds From a Three‐Component Prebiotic Mixture

Chemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.
High‐energy proton irradiation of a formamide–diaminomaleonitrile–glycine system in the presence of meteorites produces a broad spectrum of biogenic compounds, including nucleobases, nucleosides, peptides, and nucleobase–peptide conjugates, highlighting a chemically plausible prebiotic network.
Bruno Mattia Bizzarri, Rosangela Santalucia, Eleonora Mancin, Mikhail Kapralov, Eugene Krasavin, Raffaele Saladino, Ernesto Di Mauro   +6 more
wiley   +1 more source