Results 51 to 60 of about 3,583 (208)
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Pest Management Science, EarlyView.This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King +6 more
wiley +1 more source
Cyclic Octamer Peptoids: Simplified Isosters of Bioactive Fungal Cyclodepsipeptides
Molecules, 2018 Cyclic peptoids have recently emerged as an important class of bioactive scaffolds with unique conformational properties and excellent metabolic stabilities.
Assunta D’Amato +5 more
doaj +1 more source
Structure-affinity and structure-residence time relationships of macrocyclic Gαq protein inhibitors
iScience, 2023 Summary: The macrocyclic depsipeptides YM-254890 (YM) and FR900359 (FR) are potent inhibitors of Gαq/11 proteins. They are important pharmacological tools and have potential as therapeutic drugs.
Jan H. Voss +7 more
doaj +1 more source
The FEBS Journal, EarlyView.Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley +1 more source
Natural Product Communications, 2018 Two new terpenoids, saponaceolide T ( 7 ), and lanostane triterpenoid saponaceol D ( 11 ), were isolated from an EtOAc extract of Tricoloma saponaceum fruiting bodies and their structures have been established by spectroscopic analysis.
Davide Gozzini +4 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2023 The Feature-based Molecular Networking (FBMN) is a well-known approach for mapping and identifying structures and analogues. However, in the absence of prior knowledge about the molecular class, assessing specific fragments and clusters requires time ...
Denise M. Selegato +4 more
doaj +1 more source
The Spore-Surface Depsipeptide of Pithomyces sacchari [PDF]
Journal of General Microbiology, 1967 SUMMARY: The spore-surface spicules of Pithomyces sacchari contain the cyclotetra-depsipeptide, angolide.
P, Riches, A, Rothwell, D W, Russell
openaire +2 more sources
Advances in large DNA fragment assembly for microbial cell factory engineering
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Fig. 2 in Trikoveramides A-C, cyclic depsipeptides from the marine cyanobacterium Symploca hydnoides
, 2021 Fig. 2. Mass spectrometric fragmentation of trikoveramides A (1) – C (3).Published as part of Phyo, Ma Yadanar, Katermeran, Nursheena Parveen, Goh, Jun Xian & Tan, Lik Tong, 2021, Trikoveramides A-C, cyclic depsipeptides from the marine cyanobacterium ...
Tan, Lik Tong +3 more
core +1 more source