Results 31 to 40 of about 3,583 (208)
Evidence for Ion-Templation During Macrocyclooligomerization of Depsipeptides
The ion-mediated Mitsunobu macrocyclooligomerization (M-MCO) reaction of hydroxy acid depsipeptides provides small collections of cyclic depsipeptides with good mass recovery.
Suzanne M. Batiste (4994918) +1 more
core +2 more sources
The emetic syndrome of Bacillus cereus is a food intoxication caused by cereulide (CER) and manifested by emesis, nausea and in most severe cases with liver failure. While acute effects have been studied in the aftermath of food intoxication, an exposure
Marlies Decleer +7 more
doaj +1 more source
“Head-to-Side-Chain” Cyclodepsipeptides of Marine Origin
Since the late 1980s, a large number of depsipeptides that contain a new topography, referred to as “head-to-side-chain” cyclodepsipeptides, have been isolated and characterized.
Marta Pelay-Gimeno +2 more
doaj +1 more source
In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides.
Y. T. Candace Ho +28 more
doaj +1 more source
Salinamides, Antiinflammatory Depsipeptides from a Marine Streptomycete
In addition to the previously reported antiinflammatory agents salinamides A and B from the marine isolate Streptomyces sp. CNB-091, three minor peptides are described.
William Fenical (48035) +5 more
core +2 more sources
Synthesis of phosphorous analogues of tri- and tetra-depsipeptides 4 involving the Passerini reaction of diethylisocyanmethylphosphonate 3 with carbonyl compounds 2 and N-protected glycine 1 is reported.
Janusz Rachoń
doaj +1 more source
Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham +11 more
wiley +2 more sources
Synthetic strategies of phosphonodepsipeptides
Phosphonodepsipeptides are phosphorus analogues of depsipeptides and phosphonate-linked analogues of naturally occurring peptides. They are more stable than phosphonopeptides and have been widely applied as enzyme inhibitors, haptens for the production ...
Jiaxi Xu
doaj +1 more source
This study aimed to elucidate the structural congeners of natural izenamides A, B, and C (1–3) responsible for cathepsin D (CTSD) inhibition. Structurally modified izenamides were synthesized and biologically evaluated, and their biologically important ...
Hyun Su Kim +6 more
doaj +1 more source
Production of the Monamycins, Novel Depsipeptide Antibiotics [PDF]
Methods are described for the production of the monamycins by Streptomyces jamaicensis in shake flasks and jar fermentors. The effects on the fermentation of variations in p H, temperature, medium composition, volume of inoculum, and strain of the ...
M J, Hall, C H, Hassall
openaire +2 more sources

