Results 31 to 40 of about 3,583 (208)

Evidence for Ion-Templation During Macrocyclooligomerization of Depsipeptides

open access: yes, 2018
The ion-mediated Mitsunobu macrocyclooligomerization (M-MCO) reaction of hydroxy acid depsipeptides provides small collections of cyclic depsipeptides with good mass recovery.
Suzanne M. Batiste (4994918)   +1 more
core   +2 more sources

Oxygen Consumption Rate Analysis of Mitochondrial Dysfunction Caused by Bacillus cereus Cereulide in Caco-2 and HepG2 Cells

open access: yesToxins, 2018
The emetic syndrome of Bacillus cereus is a food intoxication caused by cereulide (CER) and manifested by emesis, nausea and in most severe cases with liver failure. While acute effects have been studied in the aftermath of food intoxication, an exposure
Marlies Decleer   +7 more
doaj   +1 more source

“Head-to-Side-Chain” Cyclodepsipeptides of Marine Origin

open access: yesMarine Drugs, 2013
Since the late 1980s, a large number of depsipeptides that contain a new topography, referred to as “head-to-side-chain” cyclodepsipeptides, have been isolated and characterized.
Marta Pelay-Gimeno   +2 more
doaj   +1 more source

Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin

open access: yesFrontiers in Catalysis, 2023
In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides.
Y. T. Candace Ho   +28 more
doaj   +1 more source

Salinamides, Antiinflammatory Depsipeptides from a Marine Streptomycete

open access: yes, 2016
In addition to the previously reported antiinflammatory agents salinamides A and B from the marine isolate Streptomyces sp. CNB-091, three minor peptides are described.
William Fenical (48035)   +5 more
core   +2 more sources

Phosphonanaloga von Aminosäuren und Peptiden: Synthese der Phosphonanaloga von Depsipeptiden mittels der Passerini-Reaktion.

open access: yesCHIMIA, 1983
Synthesis of phosphorous analogues of tri- and tetra-depsipeptides 4 involving the Passerini reaction of diethylisocyanmethylphosphonate 3 with carbonyl compounds 2 and N-protected glycine 1 is reported.
Janusz Rachoń
doaj   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

open access: yesAngewandte Chemie, Volume 138, Issue 26, 22 June 2026.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham   +11 more
wiley   +2 more sources

Synthetic strategies of phosphonodepsipeptides

open access: yesBeilstein Journal of Organic Chemistry, 2021
Phosphonodepsipeptides are phosphorus analogues of depsipeptides and phosphonate-linked analogues of naturally occurring peptides. They are more stable than phosphonopeptides and have been widely applied as enzyme inhibitors, haptens for the production ...
Jiaxi Xu
doaj   +1 more source

Structural Congeners of Izenamides Responsible for Cathepsin D Inhibition: Insights from Synthesis-Derived Elucidation

open access: yesMarine Drugs, 2023
This study aimed to elucidate the structural congeners of natural izenamides A, B, and C (1–3) responsible for cathepsin D (CTSD) inhibition. Structurally modified izenamides were synthesized and biologically evaluated, and their biologically important ...
Hyun Su Kim   +6 more
doaj   +1 more source

Production of the Monamycins, Novel Depsipeptide Antibiotics [PDF]

open access: yesApplied Microbiology, 1970
Methods are described for the production of the monamycins by Streptomyces jamaicensis in shake flasks and jar fermentors. The effects on the fermentation of variations in p H, temperature, medium composition, volume of inoculum, and strain of the ...
M J, Hall, C H, Hassall
openaire   +2 more sources

Home - About - Disclaimer - Privacy