Results 31 to 40 of about 5,584 (214)

Visible‐Light Sensitized Isomerization in the Lipid Bilayer Enables Activation of a Transmembrane Transporter

open access: yesAngewandte Chemie, EarlyView.
A stiff‐stilbene‐based transmembrane anion transporter is isomerized by energy transfer from a ruthenium tris(bipyridyl) photosensitizer in the lipid bilayer. This sensitized isomerization allows activation of chloride transport using visible instead of UV light, without the need to chemically modify the stiff‐stilbene photoswitch.
Julia Villalva   +6 more
wiley   +2 more sources

Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus. [PDF]

open access: yes, 2014
Anthracimycin is a recently discovered novel marine-derived compound with activity against Bacillus anthracis. We tested anthracimycin against an expanded panel of Staphylococcus aureus strains in vitro and in vivo. All strains of S.
Cunningham, Mark L   +12 more
core   +1 more source

Oxygen Consumption Rate Analysis of Mitochondrial Dysfunction Caused by Bacillus cereus Cereulide in Caco-2 and HepG2 Cells

open access: yesToxins, 2018
The emetic syndrome of Bacillus cereus is a food intoxication caused by cereulide (CER) and manifested by emesis, nausea and in most severe cases with liver failure. While acute effects have been studied in the aftermath of food intoxication, an exposure
Marlies Decleer   +7 more
doaj   +1 more source

AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells. Interference with the Akt/NF-kB survival pathway [PDF]

open access: yes, 2005
8 páginas, 5 figuras -- PAGS nros. 572-579Clinical treatment of B-cell chronic lymphocytic leukemia (B-CLL) is limited by the progressive drug resistance and nonselectivity of most drugs towards malignant cells.
Escobar-Díaz, Elisabeth   +9 more
core   +1 more source

“Head-to-Side-Chain” Cyclodepsipeptides of Marine Origin

open access: yesMarine Drugs, 2013
Since the late 1980s, a large number of depsipeptides that contain a new topography, referred to as “head-to-side-chain” cyclodepsipeptides, have been isolated and characterized.
Marta Pelay-Gimeno   +2 more
doaj   +1 more source

Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin

open access: yesFrontiers in Catalysis, 2023
In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides.
Y. T. Candace Ho   +28 more
doaj   +1 more source

Unraveling the senses of Phytophthora; leads to novel control strategies? [PDF]

open access: yes, 2009
Oomycetes cause devastating diseases on plants and animals. They cause major yield losses in many crop plants and their control heavily depends on agrochemicals. This is certainly true for the potato late blight pathogen Phytophthora infestans.
Govers, F.   +4 more
core   +2 more sources

Phosphonanaloga von Aminosäuren und Peptiden: Synthese der Phosphonanaloga von Depsipeptiden mittels der Passerini-Reaktion.

open access: yesCHIMIA, 1983
Synthesis of phosphorous analogues of tri- and tetra-depsipeptides 4 involving the Passerini reaction of diethylisocyanmethylphosphonate 3 with carbonyl compounds 2 and N-protected glycine 1 is reported.
Janusz Rachoń
doaj   +1 more source

Synthetic strategies of phosphonodepsipeptides

open access: yesBeilstein Journal of Organic Chemistry, 2021
Phosphonodepsipeptides are phosphorus analogues of depsipeptides and phosphonate-linked analogues of naturally occurring peptides. They are more stable than phosphonopeptides and have been widely applied as enzyme inhibitors, haptens for the production ...
Jiaxi Xu
doaj   +1 more source

Exploring bioactive properties of marine cyanobacteria Isolated from the Portuguese coast: high potential as a source of anticancer compounds [PDF]

open access: yes, 2013
The oceans remain a major source of natural compounds with potential in pharmacology. In particular, during the last few decades, marine cyanobacteria have been in focus as producers of interesting bioactive compounds, especially for the treatment of ...
Barreiro, Aldo   +9 more
core   +2 more sources

Home - About - Disclaimer - Privacy