Results 21 to 30 of about 3,874 (203)

Zhaoshumycins A and B, Two Unprecedented Antimycin-Type Depsipeptides Produced by the Marine-Derived Streptomyces sp. ITBB-ZKa6

open access: yesMarine Drugs, 2021
Marine actinomycetes are prolific chemical sources of complex and novel natural products, providing an excellent chance for new drug discovery. The chemical investigation of the marine-derived Streptomyces sp.
Zhikai Guo   +6 more
doaj   +1 more source

Solid-Phase Synthesis of Head to Side-Chain Tyr-Cyclodepsipeptides Through a Cyclative Cleavage From Fmoc-MeDbz/MeNbz-resins

open access: yesFrontiers in Chemistry, 2020
Cyclic depsipeptides constitute a fascinating class of natural products. Most of them are characterized by an ester formed between the β-hydroxy function of Ser/Thr -and related amino acids- and the carboxylic group of the C-terminal amino acid.
Gerardo A. Acosta   +14 more
doaj   +1 more source

Total Syntheses of Colletopeptide A and Colletotrichamide A

open access: yesMolecules, 2023
The first total syntheses of cyclic depsipeptides colletopeptide A and colletotrichamide A, have been accomplished. The key advanced intermediate, a cyclic tridepsipeptide derivative, was constructed using a sequence of transformations that features ...
Jing Chen   +4 more
doaj   +1 more source

Total Synthesis of Pagoamide A

open access: yesMolecules, 2021
The first total synthesis of the thiazole-containing cyclic depsipeptide pagoamide A, is detailed. The longest linear sequence of the liquid-phase synthesis comprises 9 long linear steps from simple known starting materials, which led to the unambiguous ...
Fusong Wu   +4 more
doaj   +1 more source

Preclinical Assessment of a 68Ga-DOTA-Functionalized Depsipeptide as a Radiodiagnostic Infection Imaging Agent

open access: yesMolecules, 2017
The study assessed a radiolabeled depsipeptide conjugate (68Ga-DOTA-TBIA101) for its potential as an imaging agent targeting infection or infection-associated inflammation. 68Ga-labeled DOTA-TBIA101 imaging was performed in (NZR1) healthy rabbits; (NZR2)
Thomas Ebenhan   +5 more
doaj   +1 more source

Cyclic depsipeptides, ichthyopeptins A and B, from Microcystis ichthyoblabe. [PDF]

open access: yes, 2007
Bioassay-guided isolation of antiviral compounds from the cultured cyanobacterium Microcystis ichthyoblabe provided two novel cyclic depsipeptides, ichthyopeptins A (1) and B (2).
Mentel, Renate   +6 more
core   +1 more source

Evidence for Ion-Templation During Macrocyclooligomerization of Depsipeptides

open access: yes, 2018
The ion-mediated Mitsunobu macrocyclooligomerization (M-MCO) reaction of hydroxy acid depsipeptides provides small collections of cyclic depsipeptides with good mass recovery.
Suzanne M. Batiste (4994918)   +1 more
core   +2 more sources

Protection-Free Strategy for the Synthesis of Boro-Depsipeptides in Aqueous Media under Microwave-Assisted Conditions

open access: yesMolecules, 2022
In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment.
Shuo-Bei Qiu   +11 more
doaj   +1 more source

Oxygen Consumption Rate Analysis of Mitochondrial Dysfunction Caused by Bacillus cereus Cereulide in Caco-2 and HepG2 Cells

open access: yesToxins, 2018
The emetic syndrome of Bacillus cereus is a food intoxication caused by cereulide (CER) and manifested by emesis, nausea and in most severe cases with liver failure. While acute effects have been studied in the aftermath of food intoxication, an exposure
Marlies Decleer   +7 more
doaj   +1 more source

A new depsipeptide antibiotic, citropeptin. [PDF]

open access: yesAgricultural and Biological Chemistry, 1990
An actinomycete identified as Streptomyces flavidovirens was found to produce a new cyclic hexadepsipeptide antibiotic, designated citropeptin. Citropeptin showed antitumor activity against P388 murine leukemia.
HAYAKAWA, Yoichi   +3 more
openaire   +3 more sources

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