Results 21 to 30 of about 5,584 (214)
Frontiers in Chemistry, 2020 Cyclic depsipeptides constitute a fascinating class of natural products. Most of them are characterized by an ester formed between the β-hydroxy function of Ser/Thr -and related amino acids- and the carboxylic group of the C-terminal amino acid.
Gerardo A. Acosta +14 more
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Total Syntheses of Colletopeptide A and Colletotrichamide A
Molecules, 2023 The first total syntheses of cyclic depsipeptides colletopeptide A and colletotrichamide A, have been accomplished. The key advanced intermediate, a cyclic tridepsipeptide derivative, was constructed using a sequence of transformations that features ...
Jing Chen +4 more
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A New Depsipeptide Antibiotic, Variapeptin [PDF]
Agricultural and Biological Chemistry, 1990 A culture similar to Streptomyces variabilis was found to produce a novel cyclic hexadepsipeptide antibiotic named variapeptin. Variapeptin is structurally related to azinothricin, A83586C, and citropeptin. The antibiotic was active against Gram-positive bacteria and showed cytotoxic activity against mammalian cells.
M, Nakagawa +3 more
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Biological activities of ethanolic extracts from deep-sea antarctic marine sponges [PDF]
, 2013 We report on the screening of ethanolic extracts from 33 deep-sea Antarctic marine sponges for different biological activities. We monitored hemolysis, inhibition of acetylcholinesterase, cytotoxicity towards normal and transformed cells and growth ...
Ambrožič Avguštin, Jerneja +9 more
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Identification of Four New agr Quorum Sensing-Interfering Cyclodepsipeptides from a Marine Photobacterium [PDF]
, 2013 During our search for new natural products from the marine environment, we discovered a wide range of cyclic peptides from a marine Photobacterium, closely related to P. halotolerans.
Anita Nielsen +7 more
core +2 more sources
Total Synthesis of Pagoamide A
Molecules, 2021 The first total synthesis of the thiazole-containing cyclic depsipeptide pagoamide A, is detailed. The longest linear sequence of the liquid-phase synthesis comprises 9 long linear steps from simple known starting materials, which led to the unambiguous ...
Fusong Wu +4 more
doaj +1 more source
Antiviral activity of animal venom peptides and related compounds [PDF]
, 2017 Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense.
Mata, Élida Cleyse Gomes da Mata +3 more
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Molecules, 2022 In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment.
Shuo-Bei Qiu +11 more
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Molecules, 2017 The study assessed a radiolabeled depsipeptide conjugate (68Ga-DOTA-TBIA101) for its potential as an imaging agent targeting infection or infection-associated inflammation. 68Ga-labeled DOTA-TBIA101 imaging was performed in (NZR1) healthy rabbits; (NZR2)
Thomas Ebenhan +5 more
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From amino acid sequence to bioactivity: the biomedical potential of antitumor peptides [PDF]
, 2016 Chemoprevention is the use of natural and/or synthetic substances to block, reverse, or retard the process of carcinogenesis. In this field, the use of antitumor peptides is of interest as, (i) these molecules are small in size, (ii) they show good cell ...
Ando +75 more
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