Results 21 to 30 of about 3,874 (203)
Marine actinomycetes are prolific chemical sources of complex and novel natural products, providing an excellent chance for new drug discovery. The chemical investigation of the marine-derived Streptomyces sp.
Zhikai Guo +6 more
doaj +1 more source
Cyclic depsipeptides constitute a fascinating class of natural products. Most of them are characterized by an ester formed between the β-hydroxy function of Ser/Thr -and related amino acids- and the carboxylic group of the C-terminal amino acid.
Gerardo A. Acosta +14 more
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Total Syntheses of Colletopeptide A and Colletotrichamide A
The first total syntheses of cyclic depsipeptides colletopeptide A and colletotrichamide A, have been accomplished. The key advanced intermediate, a cyclic tridepsipeptide derivative, was constructed using a sequence of transformations that features ...
Jing Chen +4 more
doaj +1 more source
Total Synthesis of Pagoamide A
The first total synthesis of the thiazole-containing cyclic depsipeptide pagoamide A, is detailed. The longest linear sequence of the liquid-phase synthesis comprises 9 long linear steps from simple known starting materials, which led to the unambiguous ...
Fusong Wu +4 more
doaj +1 more source
The study assessed a radiolabeled depsipeptide conjugate (68Ga-DOTA-TBIA101) for its potential as an imaging agent targeting infection or infection-associated inflammation. 68Ga-labeled DOTA-TBIA101 imaging was performed in (NZR1) healthy rabbits; (NZR2)
Thomas Ebenhan +5 more
doaj +1 more source
Cyclic depsipeptides, ichthyopeptins A and B, from Microcystis ichthyoblabe. [PDF]
Bioassay-guided isolation of antiviral compounds from the cultured cyanobacterium Microcystis ichthyoblabe provided two novel cyclic depsipeptides, ichthyopeptins A (1) and B (2).
Mentel, Renate +6 more
core +1 more source
Evidence for Ion-Templation During Macrocyclooligomerization of Depsipeptides
The ion-mediated Mitsunobu macrocyclooligomerization (M-MCO) reaction of hydroxy acid depsipeptides provides small collections of cyclic depsipeptides with good mass recovery.
Suzanne M. Batiste (4994918) +1 more
core +2 more sources
In this report, 19 boron-containing depsipeptides were synthesized via microwave-assisted Passerini three-component reaction (P-3CR) in an aqueous environment.
Shuo-Bei Qiu +11 more
doaj +1 more source
The emetic syndrome of Bacillus cereus is a food intoxication caused by cereulide (CER) and manifested by emesis, nausea and in most severe cases with liver failure. While acute effects have been studied in the aftermath of food intoxication, an exposure
Marlies Decleer +7 more
doaj +1 more source
A new depsipeptide antibiotic, citropeptin. [PDF]
An actinomycete identified as Streptomyces flavidovirens was found to produce a new cyclic hexadepsipeptide antibiotic, designated citropeptin. Citropeptin showed antitumor activity against P388 murine leukemia.
HAYAKAWA, Yoichi +3 more
openaire +3 more sources

