Results 11 to 20 of about 3,583 (208)
Small depsipeptides as solvent gelators
Journal of the Chemical Society, Chemical Communications, 1993 The formation of very thermostable gels with several solvents is reported for two cyclic depsipeptides of comparatively low molecular mass.
DEVRIES, EJ, KELLOGG, RM
core +4 more sources
Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials
Molecules, 2023 Cancer is currently considered one of the most threatening diseases worldwide. Diet could be one of the factors that can be enhanced to comprehensively address a cancer patient’s condition.
Plinio A. Trinidad-Calderón +2 more
doaj +2 more sources
A Survey of Didemnin Depsipeptide Production in Tistrella [PDF]
Marine Drugs, 2023 As one of the first families of marine natural products to undergo clinical trials, the didemnin depsipeptides have played a significant role in inspiring the discovery of marine drugs.
Robert J. Stankey +4 more
doaj +4 more sources
Fungal cyclooligomer depsipeptides [PDF]
Natural Product Reports, 2011 This review surveys the biological activities and the iterative and recursive biosynthetic mechanisms of fungal cyclooligomer depsipeptides, and their structural diversification by various combinatorial biosynthetic methods.
Süssmuth, Roderich +3 more
openaire +2 more sources
Structural Diversity and Biological Activities of Cyclic Depsipeptides from Fungi
Molecules, 2018 Cyclic depsipeptides (CDPs) are cyclopeptides in which amide groups are replaced by corresponding lactone bonds due to the presence of a hydroxylated carboxylic acid in the peptide structure.
Xiaohan Wang +4 more
doaj +2 more sources
Exploring the sequence space of unknown oligomers and polymers
Cell Reports Physical Science, 2021 Summary: The characterization of the chemistry of life on earth has been facilitated by developments in analysis and sequencing of bio-oligomers using tandem mass spectrometry (MS/MS).
David Doran +5 more
doaj +1 more source
Frontiers in Chemistry, 2023 Multicomponent reactions were performed to develop novel α,β-unsaturated carbonyl depsipeptides and peptoids incorporating various chromophores such as cinnamic, coumarin, and quinolines.
Ricelia González +9 more
doaj +1 more source
Peptides from Marine-Derived Fungi: Chemistry and Biological Activities
Marine Drugs, 2023 Marine natural products are well-recognized as potential resources to fill the pipeline of drug leads to enter the pharmaceutical industry. In this circumstance, marine-derived fungi are one of the unique sources of bioactive secondary metabolites due to
Salar Hafez Ghoran +4 more
doaj +1 more source
A contribution to the nomenclature of depsipeptides [PDF]
Journal of Peptide Science, 2003 AbstractDepsipeptides, also called peptolides, are a class of peptidic compounds in which an amide bond has been replaced with an ester bond. The literature does not clearly display rules for the nomenclature of such compounds. Here a method is proposed to transcribe drawn depsipeptide structures in one‐line text.
Sorin V, Filip, Florine, Cavelier
openaire +2 more sources
A Bidirectional Permeability Assay for beyond Rule of 5 Compounds
Pharmaceutics, 2021 Bidirectional permeability measurement with cellular models grown on Transwell inserts is widely used in pharmaceutical research since it not only provides information about the passive permeability of a drug, but also about transport proteins involved ...
Yunhai Cui +6 more
doaj +1 more source