Results 61 to 70 of about 5,584 (214)
The FEBS Journal, EarlyView.Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley +1 more source
Frontiers in ChemistryAntimicrobial depsipeptides and cyclodepsipeptides represent a structurally diverse class of natural products that have gained renewed attention as both antibacterial agents and molecular tools to interrogate bacterial physiology.
Sachin Baravkar +6 more
doaj +1 more source
Two New Cyclic Depsipeptides from the Endophytic Fungus sp
Natural Product Communications, 2015 Two new cyclic depsipeptides, W493 C (1) and D (2), along with two known derivatives W493 A (3) and B (4) were obtained from the endophytic fungus Fusarium sp. isolated from the Mangrove plant Ceriops tagal.
Fang Lv +3 more
doaj +1 more source
In situ natural product discovery via an artificial marine sponge. [PDF]
PLoS ONE, 2014 There is continuing international interest in exploring and developing the therapeutic potential of marine-derived small molecules. Balancing the strategies for ocean based sampling of source organisms versus the potential to endanger fragile ecosystems ...
James J La Clair +5 more
doaj +1 more source
Detection of inhibitors of Candida albicans Cdr transporters using a diS-C3(3) fluorescence [PDF]
, 2015 Candida albicans is a major cause of opportunistic and life-threatening, systemic fungal infections. Hence new antifungal agents, as well as new methods to treat fungal infections, are still needed.
Anna Krasowska +2 more
core +3 more sources
Advances in large DNA fragment assembly for microbial cell factory engineering
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Structural Diversity and Biological Activities of Cyclic Depsipeptides from Fungi
Molecules, 2018 Cyclic depsipeptides (CDPs) are cyclopeptides in which amide groups are replaced by corresponding lactone bonds due to the presence of a hydroxylated carboxylic acid in the peptide structure.
Xiaohan Wang +4 more
doaj +1 more source
Multi‐Targeting Non‐Specific Genome Engineering in Bacteria
Advanced Science, Volume 13, Issue 25, 4 May 2026.In this study, we provide the first case to use the multi‐targeting integrase (MTI) systems in bacteria and develop a host‐independent generalizable approach, MNGE (Multi‐targeting Non‐specific Genome Engineering), for multi‐copy and random integration of metabolic genes or pathways in both Gram‐positive and Gram‐negative bacteria, which will ...
Runze Sun +7 more
wiley +1 more source
Bioactive Peptides and Depsipeptides with Anticancer Potential: Sources from Marine Animals
Marine Drugs, 2012 Biologically active compounds with different modes of action, such as, antiproliferative, antioxidant, antimicrotubule, have been isolated from marine sources, specifically algae and cyanobacteria.
Josafat-Marina Ezquerra-Brauer +2 more
doaj +1 more source
mMass as a software tool for the annotation of cyclic peptide tandem mass spectra. [PDF]
PLoS ONE, 2012 Natural or synthetic cyclic peptides often possess pronounced bioactivity. Their mass spectrometric characterization is difficult due to the predominant occurrence of non-proteinogenic monomers and the complex fragmentation patterns observed. Even though
Timo H J Niedermeyer, Martin Strohalm
doaj +1 more source