Results 91 to 100 of about 11,998 (213)

Arterial heparan sulfate is negatively associated with hyperglycemia and atherosclerosis in diabetic monkeys

Cardiovascular Diabetology, 2004
Background Arterial proteoglycans are implicated in the pathogenesis of atherosclerosis by their ability to trap plasma lipoproteins in the arterial wall and by their influence on cellular migration, adhesion and proliferation.
Litwak Kenneth N, Vogl-Willis Catherine A, Wagner Janice D, Edwards Iris J, Cefalu William T   +4 more
doaj   +1 more source

Continuous Alterations in the Gut Microbial Landscape Associated With Suicidal Ideation in First‐Episode Drug‐naïve Major Depressive Disorder

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
We define a gut‐microbiota gradient linked to increasing depression severity and suicidal ideation, highlighting severity‐tracking taxa and pathways, particularly Bacteroides stercoris and the bacterial secretion‐system pathway, as potential microbial markers for suicide risk in MDD.
Liqin Liang, Shuhao Chen, Baoyuan Zhu, Yuanyuan Huang, Xiaodan Lu, Shuhong Wang, Wei Wang, Rui Han, Jing Zhou, Dongsheng Xiong, Hehua Li, Xiaobo Li, Yuping Ning, Fengchun Wu, Kai Wu   +14 more
wiley   +1 more source

Bacterial lyases as powerful tools to evaluate the structures of heparan sulfate, heparin and dermatan sulfate [PDF]

, 1992
Bacterial lyases as powerful tools to evaluate the structures of heparan sulfate, heparin and dermatan ...
VOLPI, Nicola, BOLOGNANI, Lorenzo
core  

Influence of Propolis-Containing Nonwoven PLGA Dressings on Dermatan and Chondroitin Sulfate Dynamics During Burn-Wound Healing

Pharmaceuticals
Background/Objectives: Burn wounds are complex injuries associated with extensive inflammation, extracellular matrix (ECM) damage, and a high risk of impaired tissue remodeling and scarring.
Kinga Orlińska, Mateusz Stojko, Jakub Włodarczyk, Janusz Kasperczyk, Oskan Tasinov, Diana Ivanova, Mladena Nikolaeva Radeva, Paweł Janik, Katarzyna Komosińska-Vassev, Krystyna Olczyk, Jerzy Stojko, Paweł Olczyk   +11 more
doaj   +1 more source

Deletion of a Pax1 Sex‐Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice

JOR SPINE, Volume 9, Issue 2, June 2026.
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody, Emma M. Wade, Shuji Mizumoto, Jeremy McCallum‐Loudeac, Megan J. Wilson   +4 more
wiley   +1 more source

Bioactive Glycosaminoglycans from Caranx crysos: A Structure–Function Study of Selective Anticoagulant Activity

Marine Drugs
Glycosaminoglycans (GAGs) are the carbohydrate portion of proteoglycans (PGS), a family of complex biomacromolecules ubiquitously found in the extracellular matrix and on cell surfaces that play critical roles in a plethora of physiological and ...
Ranim Kroumi, Soumaya Alimi, Fabiana Esposito, Asma Haffouz, Basma Hadjkacem, Angela Casillo, Anissa Haddar, Assaad Sila, Emiliano Bedini, Ali Bougatef   +9 more
doaj   +1 more source

Fully Synthetic, Biomimicking Polysulfates With Tunable Anticoagulant and Endothelial Cell–Selective Bioactivity

Macromolecular Bioscience, Volume 26, Issue 6, June 2026.
Sulfated PHEMA‐based polyelectrolyte brushes are introduced as a reductionist platform to probe glycosaminoglycan‐inspired bioactivity. High charge density governs growth factor interactions and is associated with distinct vascular cell responses, enabling balanced endothelial and smooth muscle cell co‐culture.
Andrea Cosimi, Roxana Pollehn, Andrea De Martino, Scarlett Manzke, Yannic Kerkhoff, Philip Nickl, Theresa Lohmann, Eriselda Keshi, Cornelia Lee‐Thedieck, Marie Weinhart   +9 more
wiley   +1 more source

Purification of heparin, dermatan sulfate and chondroitin sulfate from mixtures by sequential precipitation with various organic solvents [PDF]

, 1996
Heparin, dermatan sulfate and chondroitin sulfate in mixtures were fractionated by sequential precipitation with methanol, ethanol and propanol.
VOLPI, Nicola
core  

Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors

Brazilian Journal of Medical and Biological Research, 2003
Human plasma kallikrein, a serine proteinase, plays a key role in intrinsic blood clotting, in the kallikrein-kinin system, and in fibrinolysis. The proteolytic enzymes involved in these processes are usually controlled by specific inhibitors and may be ...
Gozzo A.J., Nunes V.A., Nader H.B., Dietrich C.P., Carmona A.K., Sampaio M.U., Sampaio C.A.M., Araújo M.S.   +7 more
doaj  

Identification and Signature Sequences of Bacterial Δ4,5Hexuronate-2-O-Sulfatases

Frontiers in Microbiology, 2019
Glycosaminoglycan (GAG) sulfatases, which catalyze the hydrolysis of sulfate esters from GAGs, belong to a large and conserved sulfatase family. Bacterial GAG sulfatases are essential in the process of sulfur cycling and are useful for the structural ...
Shumin Wang, Jingwen Guan, Qingdong Zhang, Xiangxue Chen, Fuchuan Li   +4 more
doaj   +1 more source