Results 81 to 90 of about 11,964 (213)

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, Volume 13, Issue 28, 18 May 2026.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

Influence of Propolis-Containing Nonwoven PLGA Dressings on Dermatan and Chondroitin Sulfate Dynamics During Burn-Wound Healing

Pharmaceuticals
Background/Objectives: Burn wounds are complex injuries associated with extensive inflammation, extracellular matrix (ECM) damage, and a high risk of impaired tissue remodeling and scarring.
Kinga Orlińska, Mateusz Stojko, Jakub Włodarczyk, Janusz Kasperczyk, Oskan Tasinov, Diana Ivanova, Mladena Nikolaeva Radeva, Paweł Janik, Katarzyna Komosińska-Vassev, Krystyna Olczyk, Jerzy Stojko, Paweł Olczyk   +11 more
doaj   +1 more source

Cleaning Matters: Impact of Surface Treatment Methods on Solid‐State Nanopore Noise for High Frequency Recording

Chemistry–Methods, Volume 6, Issue 5, May 2026.
The impact of different cleaning strategies on the noise spectrum of solid state nanopores was evaluated. Noise reduction is a key challenge in solid‐state nanopore experiments, as it directly limits signal resolution and the detectability of translocation events.
Wesley Pietsch, Marc Safferthal, Niklas Geue, Artur Uzdenov, Michael Götze, Kevin Pagel   +5 more
wiley   +1 more source

Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions

, 2019
Sulfated glycosaminoglycans (heparan sulfate, chondroitin sulfate, dermatan sulfate, and keratan sulfate) are a family of complex polysaccharides ubiquitously, but not exclusively, distributed among mammals, found both in extracellular matrices and on
Maria Michela Corsaro, Alfonso Iadonisi, Corsaro, M. M., Fernández-Mayoralas, Alfonso, Iadonisi, Alfonso, Emiliano Bedini, Alfonso Fernández-Mayoralas, Bedini, Emiliano   +7 more
core   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, Volume 45, Issue 3, Page 455-475, May/June 2026.
ABSTRACT Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Original data of phylogenetic analysis, cloning, expression, purification, specificity and biochemical characteristics of the identified chondroitin sulfate/dermatan sulfate 4-O-endosulfatase (endoBI4SF)

, 2023
This dataset includes the raw data of phylogenetic analysis, cloning, expression, purification, specificity and biochemical characteristics of the identified chondroitin sulfate/dermatan sulfate 4-O-endosulfatase (endoBI4SF) related to the published ...
Wei, L (via Mendeley Data)
core   +1 more source

Identification and Signature Sequences of Bacterial Δ4,5Hexuronate-2-O-Sulfatases

Frontiers in Microbiology, 2019
Glycosaminoglycan (GAG) sulfatases, which catalyze the hydrolysis of sulfate esters from GAGs, belong to a large and conserved sulfatase family. Bacterial GAG sulfatases are essential in the process of sulfur cycling and are useful for the structural ...
Shumin Wang, Jingwen Guan, Qingdong Zhang, Xiangxue Chen, Fuchuan Li   +4 more
doaj   +1 more source

Isolation and characterization of dermatan sulfate from various sources

, 1989
Isolation and characterization of dermatan sulfate from various ...
VOLPI, Nicola, Mascellani, G., P. ., Bianchini, B. Parma   +3 more
core  

Kinetic parameters characterizing the interactions of transglutaminase 2 (TG2) with structurally different types of dermatan sulfate (DS)/ chondroitin sulfate (CS).

, 2017
Kinetic parameters characterizing the interactions of transglutaminase 2 (TG2) with structurally different types of dermatan sulfate (DS)/ chondroitin sulfate (CS).
Tomasz Bielecki (3749440), Adam Pudełko (3749449), Krystyna Olczyk (3749446), Ewa M. Koźma (3749437), Grzegorz Wisowski (3749443)   +4 more
core   +1 more source

Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors

Brazilian Journal of Medical and Biological Research, 2003
Human plasma kallikrein, a serine proteinase, plays a key role in intrinsic blood clotting, in the kallikrein-kinin system, and in fibrinolysis. The proteolytic enzymes involved in these processes are usually controlled by specific inhibitors and may be ...
Gozzo A.J., Nunes V.A., Nader H.B., Dietrich C.P., Carmona A.K., Sampaio M.U., Sampaio C.A.M., Araújo M.S.   +7 more
doaj