Results 61 to 70 of about 232,697 (206)

Identification and Action Patterns of Two Chondroitin Sulfate Sulfatases From a Marine Bacterium Photobacterium sp. QA16

Frontiers in Microbiology, 2022
Chondroitin sulfate (CS)/dermatan sulfate (DS) is a kind of sulfated polyanionic, linear polysaccharide belonging to glycosaminoglycan. CS/DS sulfatases, which specifically hydrolyze sulfate groups from CS/DS oligo-/polysaccharides, are potential tools ...
Lin Wei, Qingdong Zhang, Qingdong Zhang, Danrong Lu, Danrong Lu, Min Du, Xiangyu Xu, Wenshuang Wang, Yu-Zhong Zhang, Xunyi Yuan, Fuchuan Li   +10 more
doaj   +1 more source

Integrated Genome‐Wide Association Studies and Selection Signature Analysis Reveal the Genetic Architecture of the Wattle Trait in Goats

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Wattles are finger‐like appendages on the ventral neck of goats, serving as a distinctive morphological marker for breed identification that serves potential implications for production performance. However, their genetic basis remains incompletely characterized.
Siyi Hu, Chen Wei, Da Feng, Shangquan Gan   +3 more
wiley   +1 more source

Engineering of Substrate-Binding Domain to Improve Catalytic Activity of Chondroitin B Lyase with Semi-Rational Design

Current Issues in Molecular Biology
Dermatan sulfate and chondroitin sulfate are dietary supplements that can be utilized as prophylactics against thrombus formation. Low-molecular-weight dermatan sulfate (LMWDS) is particularly advantageous due to its high absorbability.
Miao Tian, Yuan-Yuan Xu, Yang-Nan Li, Shen Yu, Yi-Lin Wang, Xiao-Lai Ma, Ye-Wang Zhang   +6 more
doaj   +1 more source

Collagens and proteoglycans of the corneal extracellular matrix

Brazilian Journal of Medical and Biological Research, 2003
The cornea is a curved and transparent structure that provides the initial focusing of a light image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth, covered anteriorly with epithelium and posteriorly with ...
Y.M. Michelacci
doaj   +1 more source

Isolation, N-glycosylations and Function of a Hyaluronidase-Like Enzyme from the Venom of the Spider Cupiennius salei. [PDF]

PLoS ONE, 2015
Hyaluronidases are important venom components acting as spreading factor of toxic compounds. In several studies this spreading effect was tested on vertebrate tissue. However, data about the spreading activity on invertebrates, the main prey organisms of
Olivier Biner, Christian Trachsel, Aline Moser, Lukas Kopp, Nicolas Langenegger, Urs Kämpfer, Christoph von Ballmoos, Wolfgang Nentwig, Stefan Schürch, Johann Schaller, Lucia Kuhn-Nentwig   +10 more
doaj   +1 more source

A High‐Throughput SPR‐Based Array for Quantitative Profiling of Glycosaminoglycan–Protein Interactions

Proteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT Glycosaminoglycans (GAGs) are linear, negatively charged, polysaccharides that mediate a wide variety of biologically critical interactions with proteins, underpinning growth factor signaling, extracellular matrix assembly, and numerous disease processes.
Holly L. Birchenough, Jonathan F. Popplewell, H. Davies‐Strickleton, Douglas Dyer, Anthony J. Day, Thomas A. Jowitt   +5 more
wiley   +1 more source

Dermatan sulfate reduces monocyte chemoattractant protein 1 and TGF-β production, as well as macrophage recruitment and myofibroblast accumulation in mice with unilateral ureteral obstruction

Brazilian Journal of Medical and Biological Research, 2011
Selectins play an essential role in most inflammatory reactions, mediating the initial leukocyte-rolling event on activated endothelium. Heparin and dermatan sulfate (DS) bind and block P- and L-selectin function in vitro.
C.L.R. Belmiro, R.G. Gonçalves, E.O. Kozlowski, A.F. Werneck, C.M. Takyia, M. Leite-Jr., M.S.G. Pavão   +6 more
doaj   +1 more source

Small Proteoglycans, Big Impact: Decorin, Biglycan, and Asporin in Musculoskeletal Tissue Health and Disease

Proteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT The extracellular matrix (ECM) is a dynamic and information‐rich network that integrates structural support with biochemical and mechanical signaling. Among its key regulatory components are the Small Leucine‐Rich Proteoglycans (SLRPs), a family of matrix molecules that coordinate extracellular architecture with cell signaling.
Alessandra Leone, Zsuzsa Jenei‐Lanzl, Frank Zaucke   +2 more
wiley   +1 more source

Dermatan Sulfate: A New Concept in Antithrombotic Therapy [PDF]

, 1991
This study was undertaken to explore the hypothesisthat dermatan sulfate, which catalyses thrombin inhibition byheparin cofactor II, prevents thrombosis more effectively thanheparin, which catalyses thrombin inhibition by antithrombinIII.
Ryn-McKenna, Van Joanne
core   +1 more source

Lipoprotein lipase enhances the interaction of low density lipoproteins with artery-derived extracellular matrix proteoglycans

Journal of Lipid Research, 1993
The association of plasma low density lipoproteins (LDL) with arterial proteoglycans (PG) is of key importance in LDL retention and modification in the artery wall.
IJ Edwards, IJ Goldberg, JS Parks, H Xu, WD Wagner   +4 more
doaj   +1 more source