Results 51 to 60 of about 232,697 (206)
Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal +5 more
wiley +1 more source
Kinetic parameters characterizing the interactions of transglutaminase 2 (TG2) with structurally different types of dermatan sulfate (DS)/ chondroitin sulfate (CS).
Tomasz Bielecki (3749440) +4 more
core +1 more source
Characterization of Danaparoid Complex Extractive Drug by an Orthogonal Analytical Approach
Danaparoid sodium salt, is the active component of ORGARAN, an anticoagulant and antithrombotic drug constituted of three glycosaminoglycans (GAGs) obtained from porcine intestinal mucosa extracts. Heparan sulfate is the major component, dermatan sulfate
Cristina Gardini +5 more
doaj +1 more source
ABSTRACT Introduction Bivalirudin is an alternative anticoagulant to heparin and is widely used in pediatric extracorporeal life support (ECLS). Its activity is monitored using activated partial thromboplastin time (aPTT) and/or more specific tests such as plasma‐diluted thrombin time (dTT).
Vadim Kostousov +3 more
wiley +1 more source
Glycosaminoglycan distribution in the rat uterine cervix during the estrous cycle
OBJECTIVE: To analyze the amount of glycosaminoglycans in the uterine cervix during each phase of the rat estrous cycle. DESIGN: Based on vaginal smears, forty female, regularly cycling rats were divided into four groups (n = 10 for each group): GI ...
Jairo Jose Matozinho Cubas +5 more
doaj +1 more source
A review on an imperative by-product: Glycosaminoglycans- A holistic approach
Glycosaminoglycan is a generic term for a class of minor but significant components of the body. The extraction, application, and functionalization of GAGs are essential to explore owing to their biological significance.
Bindia Sahu +4 more
doaj +1 more source
Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno +3 more
wiley +1 more source
Galactosaminoglycan Function and Oligosaccharide Structure Determination
This review will discuss the importance of sequencing long chondroitin sulfate and dermatan sulfate chains specifically derived from decorin. Decorin is a member of the small leucine-rich repeat proteoglycans and ubiquitously expressed primarily in the ...
Daniela G. Seidler +2 more
doaj +1 more source
Extracellular matrix alterations in the Peyronie’s disease
Peyronie’s disease is characterized by fibrous plaque formation of the tunica albuginea, causing penile deformity and fertility problems. The aim of the present study was to investigate alterations in the extracellular matrix in Peyronie’s disease.
Marcelo Silva Watanabe +8 more
doaj +1 more source
Alder–Reilly Anomaly Leading to Incidental Diagnosis of MPS VII in an Asymptomatic Adult
ABSTRACT Mucopolysaccharidosis type VII (MPS VII; Sly syndrome) is a rare autosomal recessive lysosomal storage disorder caused by deficiency of β‐glucuronidase due to pathogenic variants in the GUSB gene. Impaired degradation of glycosaminoglycans (GAGs) results in multiorgan dysfunction with highly variable clinical presentation, ranging from severe ...
Margaretha G. M. Roemer +5 more
wiley +1 more source

