Spatial immune heterogeneity in a mouse tumor model after immunotherapy
Cancer Science, Volume 116, Issue 3, Page 622-632, March 2025.Spatial immune heterogeneity in the tumor microenvironment and its drivers in a mouse model of tumors induced by human papillomaviruses were investigated following immunotherapy. Gene expression was determined by RNA sequencing and mutations by whole exome sequencing in different tumor areas.
Michal Smahel +4 more
wiley +1 more source
Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]
, 2019 Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Morla, Shravan
core +1 more source
Quantification of sulfated polysaccharides in mouse and rat plasma by the Heparin Red mix-and-read fluorescence assay [PDF]
arXiv, 2017 Sulfated polysaccharides constitute a large and complex group of macromolecules which possess a wide range of important biological properties. Many of them hold promise as new therapeutics, but determination of their blood levels during pharmacokinetic studies can be challenging.
arxiv
Transient Sulfate Aerosols as a Signature of Exoplanet Volcanism [PDF]
, 2015 Geological activity is thought to be important for the origin of life and for maintaining planetary habitability. We show that transient sulfate aerosols could be a signature of exoplanet volcanism, and therefore a geologically active world. A detection of transient aerosols, if linked to volcanism, could thus aid in habitability evaluations of the ...
arxiv +1 more source
Role of the Extracellular Matrix in Cancer: Insights into Tumor Progression and Therapy
Advanced Therapeutics, Volume 8, Issue 2, February 2025.The extracellular matrix (ECM) is pivotal in cancer progression, influencing tumor growth, metastasis, and therapy resistance. This paper explores ECM remodeling, highlighting components like collagens and proteoglycans, their impact on immune evasion, and emerging therapies targeting ECM mechanics and composition.
Nimeet Desai +8 more
wiley +1 more source
Coadsorption of Copper and Sulfate on Au(111) Electrodes: Monte Carlo Simulation of a Lattice-Gas Model [PDF]
In Computer Simulation Studies in Condensed Matter Physics VIII,
D.P. Landau et al. ed., Springer Proceedings in Physics (Springer, Berlin,
1995) p. 122, 1995 We report ground-state calculations and Monte Carlo simulations for a lattice-gas model of the underpotential deposition of copper on Au(111) in sulfate-containing electrolytes. In a potential range of approximately 100$\sim$150 mV, this system exhibits a $(\sqrt3\!\times\!\sqrt3)$ mixed phase with 2/3 monolayer (ML) copper and 1/3 ML sulfate.
arxiv
Eggshell‐Based Unconventional Biomaterials for Medical Applications
Advanced NanoBiomed Research, Volume 5, Issue 2, February 2025.Eggshells are an abundant and sustainable resource with exceptional mechanical and morphological characteristics. Their unique properties emphasize the versatility potential of eggshell‐based biomaterials in developing cost‐effective, nature‐inspired solutions suited for innovations in hard and soft tissue repair, drug delivery systems, and biosensor ...
Maria Eduarda Torres Gouveia +3 more
wiley +1 more source
Recommendations for the management of MPS VI: systematic evidence- and consensus-based guidance. [PDF]
, 2019 IntroductionMucopolysaccharidosis (MPS) VI or Maroteaux-Lamy syndrome (253200) is an autosomal recessive lysosomal storage disorder caused by deficiency in N-acetylgalactosamine-4-sulfatase (arylsulfatase B).
Akyol, Mehmet Umut +30 more
core
The Dermatan Sulfate Proteoglycan Decorin Modulates α2β1 Integrin and the Vimentin Intermediate Filament System during Collagen Synthesis. [PDF]
, 2012 Decorin, a small leucine-rich proteoglycan harboring a dermatan sulfate chain at its N-terminus, is involved in regulating matrix organization and cell signaling. Loss of the dermatan sulfate of decorin leads to an Ehlers-Danlos syndrome characterized by
Eckes, Beate +8 more
core +4 more sources
Correlations between Chondroitin Sulfate Physicochemical Properties and its in-vitro Absorption and Anti-inflammatory Activity [PDF]
arXiv, 2014 Here, we investigated the influence of physicochemical characteristics of chondroitin sulfate (CS) on its in vitro absorption and anti-inflammatory activity. We used eight different synthetic and natural CS samples with a range of molecular weights (7-35 kDa) and sulfation patterns.
arxiv