Ventral body wall closure: Mechanistic insights from mouse models and translation to human pathology
Developmental Dynamics, Volume 254, Issue 2, Page 102-141, February 2025.Abstract The ventral body wall (VBW) that encloses the thoracic and abdominal cavities arises by extensive cell movements and morphogenetic changes during embryonic development. These morphogenetic processes include embryonic folding generating the primary body wall; the initial ventral cover of the embryo, followed by directed mesodermal cell ...
Caroline Formstone +3 more
wiley +1 more source
Specific inhibition of binding of antistasin and [A103,106,108] antistasin 93–119 to sulfatide (Gal(3-SO4)β1-1Cer) by glycosaminoglycans [PDF]
, 1992 Leech-derived antistasin is a potent anticoagulant and antimetastatic protein that binds sulfatide (Gal(3-SO4)β1-1Cer)and sulfated polysaccharides. In this study, the synthetic fragment [A103,106,108] antistasin 93–119, which corresponds to the carboxyl ...
Brankamp, Robert G. +4 more
core +1 more source
Exploration, Volume 5, Issue 1, February 2025.We conducted a critical evaluation of decellularization techniques, quality control, cross‐linking, and modification methods for dECM scaffolds derived from different sources. The functional properties of dECM components as well as their recent applications in multi‐organ tissue engineering and biomedicine were thoroughly reviewed.
Juan Liu +9 more
wiley +1 more source
Journal of Biological Chemistry, 1986 [3H,35S]Dermatan/chondroitin sulfate glycosaminoglycans produced during culture of fibroblasts in medium containing varying concentrations of sulfate were tested for their susceptibility to chondroitin ABC lyase and chondroitin AC lyase. Chondroitin ABC lyase completely degraded [3H]hexosamine-labeled and [35S] sulfate-labeled dermatan/chondroitin ...
Donald E. Humphries +3 more
openaire +3 more sources
Analysis of Oversulfation in a Chondroitin Sulfate Oligosaccharide Fraction from Bovine Aorta by Nanoelectrospray Ionization Quadrupole Time-of-Flight and Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry [PDF]
, 2007 A combination of negative ion nano-electrospray ionization Fourier-transform ion cyclotron resonance and quadrupole time-of-flight mass spectrometry was applied to analysis of oversulfation in glycosaminoglycan oligosaccharides of the chondroitin sulfate
Kresse, Hans +4 more
core +1 more source
Effect of pH, surface charge and counter-ions on the adsorption of sodium dodecyl sulfate to the sapphire/solution interface [PDF]
, 2012 The role of ionic interactions between sodium dodecyl sulfate, SDS, and sapphire surfaces have been studied using specular neutron reflection to determine the structure and composition of adsorbed surfactant layers. Increasing the pH of the solution from 3 to 9 reduces the adsorption by reversing the charge of the alumina.
arxiv +1 more source
Vascular endothelial cell injury: causes, molecular mechanisms, and treatments
MedComm, Volume 6, Issue 2, February 2025.Endothelial cell injury is considered a critical initiating factor in the pathogenesis of various diseases, triggered by multiple factors such as disturbed shear stress and mechanical injury, environmental toxins, metabolic disorders, bacterial/viral infections, and dyslipidemia.
Tian Xia +5 more
wiley +1 more source
Heparan sulfate mediates trastuzumab effect in breast cancer cells [PDF]
, 2013 Background: Trastuzumab is an antibody widely used in the treatment of breast cancer cases that test positive for the human epidermal growth factor receptor 2 (HER2).
Del Giglio, Auro +5 more
core +2 more sources
Expression of Glycosaminoglycans and Small Proteoglycans in Wounds: Modulation by the Tripeptide–Copper Complex Glycyl-L-Histidyl-L-Lysine-Cu2+ [PDF]
, 2000 Glycyl-histidyl-lysine-Cu2+ is a tripeptide–copper complex previously shown to be an activator of wound healing. We have investigated the effects of glycyl-histidyl-lysine-Cu2+ on the synthesis of glycosaminoglycans and small proteoglycans in a model of ...
Bontemps, Yannick +3 more
core +1 more source
Identification and Signature Sequences of Bacterial Δ4,5Hexuronate-2-O-Sulfatases
Frontiers in Microbiology, 2019 Glycosaminoglycan (GAG) sulfatases, which catalyze the hydrolysis of sulfate esters from GAGs, belong to a large and conserved sulfatase family. Bacterial GAG sulfatases are essential in the process of sulfur cycling and are useful for the structural ...
Shumin Wang +4 more
doaj +1 more source