Results 61 to 70 of about 84,621 (282)

Fatty acid desaturase 2 promoter mutation is not responsible for Δ6-desaturase deficiency [PDF]

European Journal of Human Genetics, 2011
Dietary essential polyunsaturated fatty acids (PUFAs) require fatty acid desaturases (FADS) for conversion to long-chain PUFAs (LCPUFAs), which are critical for many aspects of human health. A Δ6-desaturase deficiency in a single patient was attributed to an insertion mutation in the FADS2 promoter.
Melissa K, Gregory, Susan E, Lester, Rebecca J, Cook-Johnson, Robert A, Gibson, Susanna M, Proudman, Leslie G, Cleland, Michael J, James   +6 more
openaire   +2 more sources

FADS1 FADS2 gene cluster, PUFA intake and blood lipids in children [PDF]

, 2012
Elevated cholesterol levels in children can be a risk factor for cardiovascular diseases in later life. In adults, it has been shown that blood lipid levels are strongly influenced by polymorphisms in the fatty acid desaturase (FADS) gene cluster in ...
Drogies, Tim, Schaaf, Beate, Krämer, Ursula, Thiery, Joachim, Berg, Andrea von, Buyken, Anette, Berdel, Dietrich, Bauer, Carl-Peter, Lattka, Eva, Standl, Marie, Heinrich, Joachim, Stach, Barbara, Röder, Stefan, Koletzko, Berthold, Herbarth, Olf, Koletzko, Sibylle   +15 more
core   +1 more source

Revisiting Securidaca longipedunculata Seed Oil: Applying NMR and Mass Spectroscopy to Confirm the Presence of 2‐Acetyl‐1,3‐Diacyl–sn‐Glycerols and Conjugated Hydroxydienoic Fatty Acids

Journal of the American Oil Chemists' Society, EarlyView.
The manuscript confirms and expands on previous reports concerning the presence of unusual conjugated hydroxydienoic fatty acids and acetyl‐TAG in the seed oil of Securidaca longipedunculata. The location of acetate only at sn‐2 of TAG was conclusively shown by high resolution NMR and hydroxy seed fatty acids are characterized.
Mark A. Smith, Jianfeng Zhu, Jin‐Yue Sun   +2 more
wiley   +1 more source

MicroRNA‐Seq Analysis Reveals a Critical Role for miR‐222 in Bovine Intramuscular Adipogenesis via the DDIT4/mTORC1 Axis

Animal Research and One Health, EarlyView.
Schematic diagram illustrating how miR‐222 promotes bovine intramuscular adipogenesis by targeting DDIT4 to activate the mTORC1 signaling pathway. ABSTRACT Intramuscular fat (IMF) is a key determinant of beef quality, particularly with respect to tenderness, flavor, and juiciness.
Jianbing Tan, Liang Qiu, Zhenghai Zhou, Zhipeng Zhang, Nanfei Wang, Jiangang Hao, Linsen Zan, Wucai Yang   +7 more
wiley   +1 more source

Sex pheromone evolution is associated with differential regulation of the same desaturase gene in two genera of leafroller moths. [PDF]

PLoS Genetics, 2012
Chemical signals are prevalent in sexual communication systems. Mate recognition has been extensively studied within the Lepidoptera, where the production and recognition of species-specific sex pheromone signals are typically the defining character ...
Jérôme Albre, Marjorie A Liénard, Tamara M Sirey, Silvia Schmidt, Leah K Tooman, Colm Carraher, David R Greenwood, Christer Löfstedt, Richard D Newcomb   +8 more
doaj   +1 more source

A new class of lipid desaturases: Identification of the Δ4 sphingoid base desaturase

Biochemical Society Transactions, 2002
Abstract
Garton, S., Michaelson, L. V., Beaudoin, F., Napier, J. A.   +3 more
openaire   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Palmitoleic and Dihomo-γ-Linolenic Acids Are Positively Associated With Abdominal Obesity and Increased Metabolic Risk in Children

Frontiers in Pediatrics, 2021
Background: The impact of abdominal obesity (AO) on plasma fatty acid changes and cardiometabolic risk in children who are obese and overweight has rarely been investigated.
Man-Chin Hua, Man-Chin Hua, Hui-Min Su, Ming-Wei Lai, Ming-Wei Lai, Tsung-Chieh Yao, Tsung-Chieh Yao, Ming-Han Tsai, Ming-Han Tsai, Sui-Ling Liao, Sui-Ling Liao, Shen-Hao Lai, Shen-Hao Lai, Jing-Long Huang, Jing-Long Huang   +14 more
doaj   +1 more source

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise, Lena‐Marie Eberle, Holger Laux, Kerstin Otte   +3 more
wiley   +1 more source

Functional identification of a delta8-sphingolipid desaturase from Borago officinalis

, 2001
The similarities between Δ12- and Δ15-fatty acyl desaturase sequences were used to construct degenerate primers for PCR experiments with cDNA transcribed from mRNA of developing borage seeds.
Heinz, E., Libisch, B., Napier, J. A., Zahringer, U., Sperling, P.   +4 more
core   +1 more source