Results 41 to 50 of about 84,621 (282)

Functional identification of a fatty acid Δ5 desaturase gene from Caenorhabditis elegans [PDF]

, 1998
We have identified a cDNA from the nematode worm Caenorhabditis elegans that encodes a fatty acid Δ5 desaturase. Saccharomyces cerevisiae expressing the full-length cDNA was able to convert di-homo-γ-linolenic acid to arachidonic acid, thus confirming Δ5
Lewis, Mervyn, Michaelson, L. V., Napier, Johnathan A., Mervyn Lewis, Colin M. Lazarus, Griffiths, Gareth, Lazarus, Colin M., Lazarus, C. M., Johnathan A. Napier, Michaelson, Louise V., Louise V. Michaelson, Stobart, A. K., Stobart, A.Keith, A.Keith Stobart, Napier, J. A., Griffiths, G., Gareth Griffiths, Lewis, M.   +17 more
core   +1 more source

Fucoxanthin promotes the chain lengthening reaction of polyunsaturated fatty acids in vivo by enhancing FADS2 enzyme activity

Food Science and Human Wellness
Alpha-linolenic acid (ALA) is capable of synthesizing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in vivo, but the conversion rate is hard to meet the body's need for rapid DHA supplementation.
Xiaoyue Li, Tianxin Yang, Yingcai Zhao, Chengcheng Wang, Changhu Xue, Teruyoshi Yanagita, Yuming Wang, Tiantian Zhang   +7 more
doaj   +1 more source

Isolation of a Delta(5)-fatty acid desaturase gene from Mortierella alpina [PDF]

, 1998
Arachidonic acid (C20:4 Δ5,8,11,14)) is a polyunsaturated fatty acid synthesized by the ?-fatty acid desaturation of di-homo-?-linolenic acid (C20:3 Δ8,11,14)).
Michaelson, L. V., Michaelson, Louise V., Stobart, A. K., Napier, Johnathan A., Stobart, A.Keith, Napier, J. A., Griffiths, G., Griffiths, Gareth, Lazarus, C. M., Lazarus, Colin M.   +9 more
core   +1 more source

Nothing can replace polyunsaturated lipids

eLife
Genetic studies reveal that polyunsaturated lipids do more than simply increase the fluidity of the cell membrane.
Sofia Rodriguez-Gallardo, Takeshi Harayama   +1 more
doaj   +1 more source

Expression Profiling of Lipolytic and Long-Chain Fatty Acid Biosynthesis Genes in Catfish Larvae Fed With Graded Lipid Levels

Frontiers in Marine Science, 2020
This study was designed to evaluate the effect of dietary lipid levels on the mRNA transcripts of lipid metabolic regulatory genes. Nine combinations of experimental diets containing graded lipid (80, 100, and 120 g/kg) and protein (450, 500, and 550 g ...
Ishfaq Nazir Mir, P. P. Srivastava, Irfan Ahmad Bhat, Jaffer Yousuf Dar, Deepak Agarwal   +4 more
doaj   +1 more source

Functional Characterization of a Higher Plant Sphingolipid Δ4-Desaturase: Defining the Role of Sphingosine and Sphingosine-1-Phosphate in Arabidopsis [PDF]

, 2008
The role of Δ4-unsaturated sphingolipid long-chain bases such as sphingosine was investigated in Arabidopsis (Arabidopsis thaliana). Identification and functional characterization of the sole Arabidopsis ortholog of the sphingolipid Δ4-desaturase was ...
Warnecke, D., Sperling, Petra, Haslam, Richard P., Mugford, S., Napier, Johnathan A., Sperling, P., Sarah Mugford, Albrecht, S., Johnathan A. Napier, Petra Sperling, Richard P. Haslam, Simone Zäuner, Michaelson, L. V., Desikan, R., Haslam, R. P., Sandra Albrecht, Radhika Desikan, Dirk Warnecke, Albrecht, Sandra, Markham, J. E., Heinz, E., Warnecke, Dirk, E. Heinz, Desikan, Radhika, Michaelson, Louise V., Louise V. Michaelson, Markham, Jennifer E., Zauner, S., Zäuner, Simone, Napier, J. A., Mugford, Sarah, Jennifer E. Markham   +31 more
core   +1 more source

The NASA Twins Study: The Effect of One Year in Space on Long-Chain Fatty Acid Desaturases and Elongases

Lifestyle Genomics, 2020
Background: At present, there is no clear understanding of the effect of long-duration spaceflight on the major enzymes that govern the metabolism of omega-6 and omega-3 fatty acids.
Michael A. Schmidt, Cem Meydan, Caleb M. Schmidt, Ebrahim Afshinnekoo, Christopher E. Mason   +4 more
doaj   +1 more source

Origin and evolution of fatty acid desaturase genes in oil crop Brassica napus

Oil Crop Science, 2022
Fatty acid (FA) desaturases, as the key enzymes in lipid metabolism, are responsible for biosynthesis of the unsaturated fatty FAs, which play important roles in maintaining cell membrane integrity and multiple stress responses.
Wei Zhao, Lunwen Qian, Mei Guan, Jun Liu, Chunyun Guan   +4 more
doaj   +1 more source

Enzymes enabling the biosynthesis of various C20 polyunsaturated fatty acids in a sea urchin Hemicentrotus pulcherrimus

Open Biology
Sea urchins, integral to marine ecosystems and valued as a delicacy in Asia and Europe, contain physiologically important long-chain (>C20) polyunsaturated fatty acids (PUFA) in their gonads, including arachidonic acid (ARA, 20:4n-6), eicosapentaenoic ...
Yingying Peng, Yutaka Haga, Naoki Kabeya
doaj   +1 more source

Inventory of Fatty Acid Desaturases in the Pennate Diatom Phaeodactylum tricornutum

Marine Drugs, 2015
The diatom Phaeodactylum is rich in very long chain polyunsaturated fatty acids (PUFAs). Fatty acid (FA) synthesis, elongation, and desaturation have been studied in depth in plants including Arabidopsis, but for secondary endosymbionts the full picture ...
Lina-Juana Dolch, Eric Maréchal
doaj   +1 more source