Results 51 to 60 of about 80,074 (304)

A vertebrate fatty acid desaturase with delta5 and delta6 activities [PDF]

, 2001
Δ5 and Δ6 fatty acid desaturases are critical enzymes in the pathways for the biosynthesis of the polyunsaturated fatty acids (PUFA) arachidonic, eicosapentanoic and docosahexanoic acids.
Sargent, John R, Teale, Alan J, Tocher, Douglas R, Agaba, Morris K, Hastings, Nicola, Leaver, Michael, Dick, James R   +6 more
core   +1 more source

Origin and evolution of fatty acid desaturase genes in oil crop Brassica napus

Oil Crop Science, 2022
Fatty acid (FA) desaturases, as the key enzymes in lipid metabolism, are responsible for biosynthesis of the unsaturated fatty FAs, which play important roles in maintaining cell membrane integrity and multiple stress responses.
Wei Zhao, Lunwen Qian, Mei Guan, Jun Liu, Chunyun Guan   +4 more
doaj   +1 more source

Inventory of Fatty Acid Desaturases in the Pennate Diatom Phaeodactylum tricornutum

Marine Drugs, 2015
The diatom Phaeodactylum is rich in very long chain polyunsaturated fatty acids (PUFAs). Fatty acid (FA) synthesis, elongation, and desaturation have been studied in depth in plants including Arabidopsis, but for secondary endosymbionts the full picture ...
Lina-Juana Dolch, Eric Maréchal
doaj   +1 more source

Isolation and transcriptomic analysis of Anopheles gambiae oenocytes enables the delineation of hydrocarbon biosynthesis

eLife, 2020
The surface of insects is coated in cuticular hydrocarbons (CHCs); variations in the composition of this layer affect a range of traits including adaptation to arid environments and defence against pathogens and toxins.
Linda Grigoraki, Xavier Grau-Bové, Henrietta Carrington Yates, Gareth J Lycett, Hilary Ranson   +4 more
doaj   +1 more source

Forward genetics in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency

eLife
Polyunsaturated fatty acids (PUFAs) are essential for mammalian health and function as membrane fluidizers and precursors for signaling lipids, though the primary essential function of PUFAs within organisms has not been established.
Delaney Kaper, Uroš Radović, Per-Olof Bergh, August Qvist, Marcus Henricsson, Jan Borén, Marc Pilon   +6 more
doaj   +1 more source

An unusual desaturase in Aquilegia vulgaris

Biochemical Society Transactions, 2000
Aquilegia vulgaris seed oil contains high levels of the rare fatty acid columbinic acid (18:3 Δ5,9,12), which is unusual in having the double bond at the Δ5 carbon in the trans configuration. Columbinic acid was found to be a seed-specific fatty acid not only present in the storage oil but also in membrane lipids.
Longman, A. J., Michaelson, L. V., Sayanova, O. V., Napier, J. A., Stobart, A. K.   +4 more
openaire   +2 more sources

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

Fucoxanthin promotes the chain lengthening reaction of polyunsaturated fatty acids in vivo by enhancing FADS2 enzyme activity

Food Science and Human Wellness
Alpha-linolenic acid (ALA) is capable of synthesizing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in vivo, but the conversion rate is hard to meet the body's need for rapid DHA supplementation.
Xiaoyue Li, Tianxin Yang, Yingcai Zhao, Chengcheng Wang, Changhu Xue, Teruyoshi Yanagita, Yuming Wang, Tiantian Zhang   +7 more
doaj   +1 more source

Polyunsaturated Fatty Acid Biosynthesis Involving Δ8 Desaturation and Differential DNA Methylation of FADS2 Regulates Proliferation of Human Peripheral Blood Mononuclear Cells

Frontiers in Immunology, 2018
Polyunsaturated fatty acids (PUFAs) are important for immune function. Limited evidence indicates that immune cell activation involves endogenous PUFA synthesis, but this has not been characterised.
Charlene M. Sibbons, Charlene M. Sibbons, Nicola A. Irvine, J. Eduardo Pérez-Mojica, Philip C. Calder, Karen A. Lillycrop, Barbara A. Fielding, Graham C. Burdge   +7 more
doaj   +1 more source

Desaturase Genes And Their Use (Patent WO 1999/027111 A1) [PDF]

, 1999
cDNA encoding C. elegans DELTA desaturase has been cloned and sequenced, and the DELTA desaturase amino acid sequence has been determined. The C. elegans DELTA desaturase has a surprisingly low level of sequence identity with the known borage DELTA ...
Napier, J. A.
core