Novel Fatty Acid Desaturases And Elongases And Uses Thereof (Patent CA 2768082 A1)
The invention provides isolated nucleic acid molecules which encode novel fatty acid desaturases and elongases from the organism Emiliana huxleyi. The invention also provides recombinant expression vectors containing desaturase or elongase nucleic acid ...
Sayanova, O. V. +2 more
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Desaturases And Process For The Production Of Polyunsaturated Fatty Acids In Transgenic Organisms (Patent US 9139854 B2) [PDF]
The present invention relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerin and Hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of ...
Senger, T., Napier, J. A., Bauer, J.
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Comparison of conserved motifs in Δ9 desaturases from diatoms.
Comparison of conserved motifs in Δ9 desaturases from diatoms.
Masaki Muto (454479) +6 more
core +1 more source
Infection mechanisms of Rhizoctonia cerealis in wheat
We discover that R. cerealis (Rc) is a primary pathogen causing sharp eyespot of wheat after 335 distinct isolates were isolated from 1683 SE‐diseased wheat plants across China over 7 years using a single hyphal tip isolation method. We then generated high‐quality reference genomes via de novo sequencing of five representative Rc isolates and ...
Yan Ren +13 more
wiley +1 more source
Three, two, one yeast fatty acid desaturases: regulation and function
Fatty acid composition of biological membranes functionally adapts to environmental conditions by changing its composition through the activity of lipid biosynthetic enzymes, including the fatty acid desaturases.
Lina Riego-Ruiz +5 more
core +1 more source
Decoding ferroptosis via integrated multi‐omics analyses in rice blast
The rice‐Magnaporthe oryzae pathosystem is presented as a host‐pathogen ferroptosis model. Multi‐omics insights connect ferroptosis to several cellular processes, such as iron homeostasis, reactive oxygen species (ROS)/redox imbalance, and polyunsaturated fatty acid‐containing phospholipid (PUFA‐PL) peroxidation, under multiple regulators in rice and M.
Zhibin Liang +8 more
wiley +1 more source
The purpose of this work was to study whether rat lactating mammary gland can synthesize PUFAs through the expression of Δ5 and Δ6 desaturases (Δ5D and Δ6D), whether these enzymes are regulated by the transcription factors sterol-regulatory element ...
Maricela Rodriguez-Cruz +4 more
doaj +1 more source
Desaturases And Process For The Production Of Polyunsaturated Fatty Acids In Transgenic Organisms (Patent WO 2010/066703 A2) [PDF]
The present invention relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerina and Hyaloperonospora parasitica, which code for desaturases and which can be employed for the recom bi nant production ...
Napier, J. A.
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Fatty Acid Desaturases, Polyunsaturated Fatty Acid Regulation, and Biotechnological Advances
Polyunsaturated fatty acids (PUFAs) are considered to be critical nutrients to regulate human health and development, and numerous fatty acid desaturases play key roles in synthesizing PUFAs.
Je Lee +3 more
core +1 more source
ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang +5 more
wiley +1 more source

