Results 101 to 110 of about 9,563 (231)

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

open access: yesPhytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao   +11 more
wiley   +1 more source

Ozone‐driven degradation of sex pheromone in Plutella xylostella: Implications for reproductive communication and mating success

open access: yesInsect Science, EarlyView.
In this study, we examined whether realistic ozone concentrations can interfere with sexual communication in the insect pest Plutella xylostella, the diamondback moth. Ozone exposure caused a degradation of pheromone components, leading to significant changes in blend composition and component ratios.
Francesco Sorrentino   +3 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

open access: yesAndrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer   +2 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Desaturases And Process For The Production Of Polyunsaturated Fatty Acids In Transgenic Organisms (Patent EP 2669380 A1)

open access: yes, 2013
The present invention relates to polynucleotides, particularly from Hyaloperonospora parasitica , which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids.
Senger, T., Napier, J. A., Bauer, J.
core  

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff   +3 more
wiley   +1 more source

In vitro IC50 values (nM) for fatty acid desaturases.

open access: yes, 2016
In vitro IC50 values (nM) for fatty acid desaturases.
Ikuo Miyahisa (1870795)   +7 more
core   +1 more source

A lipid‐sensitive food choice behavior influences aging outcomes from a longevity‐promoting diet

open access: yesThe FEBS Journal, EarlyView.
C. elegans are exposed to a variety of bacteria in their natural environment and must be able to distinguish between beneficial and detrimental food sources. We show that C. elegans exposed to the bacterium from their natural habitat, Methylobacterium, disrupts lipid homeostasis, causing worms to avoid this bacterial species and choose the laboratory ...
Nicole L. Stuhr   +4 more
wiley   +1 more source

Precision protease (PP) digestion of recombinant desaturases.

open access: yes, 2013
(A) Recombinant FADS proteins were digested with PP and visualized by Coomassie blue staining. Triangles indicate the recombinant desaturases before and after PP digestion. Arrow indicates Precision protease proteins. M: protein marker.
Haiqin Chen (193169)   +6 more
core   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

open access: yesThe FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén   +11 more
wiley   +1 more source

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