Results 1 to 10 of about 2,962 (112)
A workflow to explore elongase diversity and extend the repertoire of fatty acids produced by Yarrowia lipolytica [PDF]
Microbial Cell FactoriesBackground Fatty acids display highly diverse structures that confer these molecules unique chemical properties and distinct physiological functions.
Jérémy Le Reun +5 more
doaj +2 more sources
Marine Drugs, 2021 Long-chain (C20–24) polyunsaturated fatty acids (LC-PUFAs) are essential nutrients that are mostly produced in marine ecosystems. Previous studies suggested that gammarids have some capacity to endogenously produce LC-PUFAs.
Juan Carlos Navarro +2 more
exaly +3 more sources
Characterization of Three Types of Elongases from Different Fungi and Site-Directed Mutagenesis [PDF]
Journal of FungiFatty acid elongases play crucial roles in synthesizing long-chain polyunsaturated fatty acids. Identifying more efficient elongases is essential for enhancing oleaginous microorganisms to produce high yields of target products.
Yuxin Wang +5 more
doaj +2 more sources
The repertoire of desaturases and elongases reveals fatty acid variations in 56 eukaryotic genomess⃞
Journal of Lipid Research, 2008 The repertoire of biosynthetic enzymes found in an organism is an important clue for elucidating the chemical structural variations of various compounds.
Minoru Kanehisa +2 more
exaly +3 more sources
A comprehensive review of the family of very-long-chain fatty acid elongases: structure, function, and implications in physiology and pathology [PDF]
European Journal of Medical Research, 2023 Background The very-long-chain fatty acid elongase (ELOVL) family plays essential roles in lipid metabolism and cellular functions. This comprehensive review explores the structural characteristics, functional properties, and physiological significance ...
Xiangyu Wang +4 more
doaj +2 more sources
Engineering yeast for tailored fatty acid profiles [PDF]
Applied Microbiology and BiotechnologyThe demand for sustainable and eco-friendly alternatives to fossil and plant oil-derived chemicals has spurred interest in microbial production of lipids, particularly triacylglycerols, fatty acids, and their derivatives.
Simon Kobalter +2 more
doaj +2 more sources
Elongation capacity of polyunsaturated fatty acids in the annelid Platynereis dumerilii [PDF]
Open BiologyElongation of very long-chain fatty acid (Elovl) proteins plays pivotal functions in the biosynthesis of the physiologically essential long-chain polyunsaturated fatty acids (LC-PUFA).
Marc Ramos-Llorens +6 more
doaj +2 more sources
Lipid and fatty acid metabolism in trypanosomatids
Microbial Cell, 2021 Trypanosomiases and leishmaniases are neglected tropical diseases that have been spreading to previously non-affected areas in recent years. Identification of new chemotherapeutics is needed as there are no vaccines and the currently available treatment ...
Giovana Parreira de Aquino +3 more
doaj +1 more source
Marine Drugs, 2021 The production of polyunsaturated fatty acids (PUFA) in Tisochrysis lutea was studied using the gradual incorporation of a 13C-enriched isotopic marker, 13CO2, for 24 h during the exponential growth of the algae.
Marine Remize +9 more
doaj +1 more source
Brain Sciences, 2022 One line of research on the possible ways of inhibiting the growth of glioblastoma multiforme (GBM), a brain tumor with a very poor prognosis, is the analysis of its metabolism, such as fatty acid synthesis by desaturases and elongases.
Jan Korbecki +7 more
doaj +1 more source