Results 11 to 20 of about 3,553 (153)

Functional characterization and differential nutritional regulation of putative Elovl5 and Elovl4 elongases in large yellow croaker (Larimichthys crocea) [PDF]

Scientific Reports, 2017
In the present study, two elongases, Elovl4 and Elovl5, were functionally characterized and their transcriptional regulation in response to n-3 LC-PUFA administration were investigated in vivo and in vitro.
Songlin Li, Óscar Monroig, Tianjiao Wang, Yuhui Yuan, Juan Carlos Navarro, Francisco Hontoria, Kai Liao, Douglas R. Tocher, Kangsen Mai, Wei Xu, Qinghui Ai   +10 more
doaj   +2 more sources

Paving the Way for Plant-Based Bioproduction of (Z)-13-Octadecenoic Moth Pheromone Compounds. [PDF]

Plant Biotechnol J
ABSTRACT Sex pheromones are eco‐friendly agents to control pest insects. Yet, the cost of synthetic pheromone production has restricted their use essentially to high value crops. Plant‐based bioproduction of pheromone compounds offers a promising and sustainable alternative, opening up for the deployment of pheromone‐mediated pest control also in row ...
Liu M, Li H, Jin H, Xiao Y, He P, Tan C, Wang HL, Lassance JM, Löfstedt C, Ding BJ.   +9 more
europepmc   +2 more sources

Assessing the Impact of Multigene Engineering on the Proteome: Omega-3 Camelina as a Case Study. [PDF]

Plant Biotechnol J
Plant Biotechnology Journal, Volume 24, Issue 10, Page 5480-5482, October 2026.
Zhang H, Napier JA, Theodoulou FL.
europepmc   +2 more sources

Molecular characterization of biosynthesis of polyunsaturated fatty acids during different developmental stages in the copepod Apocyclops royi

Aquaculture Reports, 2022
Copepod Apocyclops royi can biosynthesize long-chain polyunsaturated fatty acids (LC-PUFAs) when fed low-PUFA precursors. Previously, two elongases and two desaturases in the n-3 PUFA biosynthetic pathway were identified from A. royi.
Piti Amparyup, Supakarn Sungkaew, Walaiporn Charoensapsri, Paveena Tapaneeyaworawong, Parichat Chumtong, Patchari Yocawibun, Prarthana Pantong, Ratree Wongpanya, Chanprapa Imjongjirak, Sorawit Powtongsook   +9 more
doaj   +1 more source

Examination of gammarid transcriptomes reveals a widespread occurrence of key metabolic genes from epibiont bdelloid rotifers in freshwater species

Open Biology, 2023
Previous data revealed the unexpected presence of genes encoding for long-chain polyunsaturated fatty acid (LC-PUFA) biosynthetic enzymes in transcriptomes from freshwater gammarids but not in marine species, even though closely related species were ...
Alberto Ribes-Navarro, Naoki Kabeya, L. Filipe C. Castro, André Gomes-dos-Santos, Miguel M. Fonseca, Hilke Alberts-Hubatsch, Francisco Hontoria, Juan C. Navarro, Óscar Monroig   +8 more
doaj   +1 more source

Saturated very long chain fatty acids are required for the production of infectious human cytomegalovirus progeny. [PDF]

PLoS Pathogens, 2013
Human cytomegalovirus hijacks host cell metabolism, increasing the flux of carbon from glucose to malonyl-CoA, the committed precursor to fatty acid synthesis and elongation. Inhibition of acetyl-CoA carboxylase blocks the production of progeny virus. To
Emre Koyuncu, John G Purdy, Joshua D Rabinowitz, Thomas Shenk   +3 more
doaj   +1 more source

Lipidomic analysis of cancer cells cultivated at acidic pH reveals phospholipid fatty acids remodelling associated with transcriptional reprogramming

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Cancer cells need to modulate the biosynthesis of membrane lipids and fatty acids to adapt themselves to an accelerated rate of cell division and survive into an extracellular environment characterised by a low pH.
Lorena Urbanelli, Sandra Buratta, Mariantonia Logozzi, Nico Mitro, Krizia Sagini, Rossella Di Raimo, Donatella Caruso, Stefano Fais, Carla Emiliani   +8 more
doaj   +1 more source

Elongases of Long-Chain Fatty Acids ELO2 and ELO9 Are Involved in Cuticle Formation and Function in Fecundity in the Yellow Fever Mosquito, Aedes aegypti

Insects, 2023
Long-chain fatty acid elongases (ELOs) play important roles in the metabolism of fatty acids in insects. In this study, the genes for two elongases from Aedes aegypti were identified, AeELO2 and AeELO9.
Jing Chen, Yu-Chen Wu, Jiu-Kai Chen, Xiao-Jing Zhu, David Merkler, Cheng-Hong Liao, Qian Han   +6 more
doaj   +1 more source

Differentiation-related changes in lipid classes with long-chain and very long-chain polyenoic fatty acids in rat spermatogenic cells[S]

Journal of Lipid Research, 2010
In rat seminiferous tubules (ST), cells that contain polar and neutral lipids with long-chain polyenoic fatty acids (PUFA) and sphingomyelins (SM) and ceramides (Cer) with very long chain (VLC) PUFA of the n-6 series coexist.
Gerardo M. Oresti, Juan G. Reyes, Jessica M. Luquez, Nelson Osses, Natalia E. Furland, Marta I. Aveldaño   +5 more
doaj   +1 more source

A complete enzymatic capacity for biosynthesis of docosahexaenoic acid (DHA, 22 : 6n–3) exists in the marine Harpacticoida copepod Tigriopus californicus

Open Biology, 2021
The long-standing paradigm establishing that global production of Omega-3 (n–3) long-chain polyunsaturated fatty acids (LC-PUFA) derived almost exclusively from marine single-cell organisms, was recently challenged by the discovery that multiple ...
Naoki Kabeya, Masanari Ogino, Hideki Ushio, Yutaka Haga, Shuichi Satoh, Juan C. Navarro, Óscar Monroig   +6 more
doaj   +1 more source