Results 41 to 50 of about 18,739,280 (231)
Contemporary Oncology, 2016 Aim of the study : Despite advances in surgical and radiotherapy techniques, the presence of lymph node metastasis drastically decreases the survival rate of patients with primary oral squamous cell carcinoma (OSCC).
Shruti Nagvekar +2 more
doaj +2 more sources
Desmoglein 3-Dependent Signaling Regulates Keratinocyte Migration and Wound Healing. [PDF]
Journal of Investigative Dermatology, 2016 The desmosomal transmembrane adhesion molecules desmoglein 3 (Dsg3) and desmocollin 3 (Dsc3) are required for strong keratinocyte cohesion. Recently, we have shown that Dsg3 associates with p38 mitogen-activated protein kinase (p38MAPK) and suppresses its activity.
Vera Rötzer +7 more
semanticscholar +3 more sources
Desmoglein autoantibodies and disease severity in pemphigus patients – correlations and discrepancies [PDF]
Folia Medica, 2023 Aim: To assess the correlation between the levels of anti-desmoglein-1 and anti-desmoglein-3 autoantibodies and disease severity in pemphigus patients.
Zhaneta H. Zhelyazkova +4 more
doaj +3 more sources
Tissue-specific effects of an anti-desmoglein-3 ADCC antibody due to expression of the target antigen and physiological characteristics of the mouse vagina [PDF]
J Toxicol Pathol, 2019 Etsuko Fujii +6 more
openalex +3 more sources
Detection of Desmoglein-3 Auto-Antibodies in Patients with Lichen Planus [PDF]
Egyptian Journal of Medical Research, 2022 There is controversy about the role of auto anti-bodies against desmoglein 3 (Dsg 3) in the pathogenesis of lichen planus (LP). The goal of this study is to detect desmoglein-3 auto-antibodies in lichen planus patients comparted to normal control persons
Abd-El Aziz El-Rifaie +3 more
doaj +1 more source
Desmoglein 3 Order and Dynamics in Desmosomes Determined by Fluorescence Polarization Microscopy. [PDF]
Biophys J, 2017 Emily I. Bartle +3 more
semanticscholar +2 more sources
Desmoglein 3 (Dsg3) expression in cancer: A tissue microarray study on 15,869 tumors.
Pathology, Research and Practice, 2022 Desmoglein-3 (Dsg3) is a transmembrane glycoprotein which is preferably found in desmosomes of keratinocytes in squamous epithelium. Both loss and upregulation of Dsg3 have been implicated in cancer progression.
F. Viehweger +24 more
semanticscholar +1 more source
Journal of Investigative Dermatology, 2022 Pemphigus vulgaris (PV) is a severe autoimmune blistering disease characterized by IgG autoantibodies (auto-ab) against the desmosomal adhesion molecules desmoglein 3 (Dsg3) and Dsg1. Underlying mechanisms leading to blister formation upon binding of Dsg-
C. Hudemann +13 more
semanticscholar +1 more source
Frontiers in Immunology, 2023 Pemphigus vulgaris (PV) is an acquired autoimmune blistering disease characterized by the production of autoantibodies targeting desmosomal cadherins, primarily desmoglein 1 and desmoglein 3, leading to acantholysis. The etiology of PV is multifactorial,
Ines Lakoš Jukić +4 more
doaj +1 more source