Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus
Frontiers in Immunology, 2019 Pemphigus vulgaris (PV) is a life-threatening mucocutaneous autoimmune blistering disease. It is often associated with autoantibodies to the desmosomal adhesion proteins Desmoglein 3 (DSG3) and Desmoglein 1 (DSG1).
Roberta Lotti +6 more
doaj +1 more source
Lesions of pemphigus vulgaris on irradiated skin [PDF]
, 2009 Summary Pemphigus vulgaris (PV) is an autoimmune blistering disease produced by IgG autoantibodies against desmoglein (Dsg)3. Lesions on the skin and mucosa can, in rare cases, be induced by radiotherapy.
Aguado, L. (Leyre) +4 more
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Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice
Allergy, EarlyView.Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek +7 more
wiley +1 more source
Lots of autoantibodies equal lupus? [PDF]
, 2013 Autoantibodies may be found years before an autoimmune disease becomes clinically apparent. For systemic lupus erythematosus (SLE), those to RNA-binding proteins, to phospholipids, and to double-stranded DNA, in particular, have been found in sera of SLE
Aringer, M, Vital, E
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Contemporary Oncology, 2016 Aim of the study : Despite advances in surgical and radiotherapy techniques, the presence of lymph node metastasis drastically decreases the survival rate of patients with primary oral squamous cell carcinoma (OSCC).
Shruti Nagvekar +2 more
doaj +1 more source
The role of nitric oxide synthases in pemphigus vulgaris in a mouse model [PDF]
, 2008 Pemphigus vulgaris (PV) is a blistering autoimmune disease characterized by IgG autoantibodies against desmoglein 3. Nitric oxide synthases (NOS) may contribute to the increase of inflammation in tissues by the generation of ...
España, A. (Agustín) +3 more
core +1 more source
The FEBS Journal, EarlyView.We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson +5 more
wiley +1 more source
Autoimmun betegségekben szerepet játszó új, diagnosztikus epitópok, valamint Fc receptorhoz kötődő és effektor funkciót kiváltó IgG Fc peptidkimérák azonosítása, szintézise és funkcionális jellemzése = Identification, synthesis and functional characterisation of new, diagnostic epitopes in autoimmune diseases, and of IgG Fc peptide chimeras binding to Fc receptor and triggering effector function [PDF]
, 2011 Autoimmun hólyagos bőrbetegségekre jellemző B- és T-sejt epitóppeptideket szintetizáltunk szilárdfázisú peptidszintézissel, Fmoc/tBu stratégiával. A peptideket tisztítottuk, azonosítottuk.
Bartos, Ádám +6 more
core
Quantitative proteomic analysis of sphere-forming stem-like oral cancer cells. [PDF]
, 2013 IntroductionThe purpose of this study is to identify target proteins that may play important functional roles in oral cancer stem-like cells (CSCs) using mass spectrometry-based quantitative proteomics.MethodsSphere-formation assays were performed on ...
Feng, Sizhe +3 more
core +1 more source
International Journal of Cosmetic Science, EarlyView.Ageing causes actin cytoskeleton disorganization, a reduction in cellular components associated with the actin cytoskeleton and focal adhesions, and a reduction in skin firmness. Galactomyces ferment filtrate boosts actin stability, increases expression of anchoring junction proteins, including focal adhesions and protects against loss of firmness ...
Steph Crabtree +12 more
wiley +1 more source