Results 91 to 100 of about 1,813 (210)

A Case Report of a Patient With Recalcitrant Pemphigus Vulgaris Treated With Rituximab

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Pemphigus vulgaris may demonstrate differential treatment responses across disease sites. In this case, cutaneous lesions responded to high‐dose corticosteroids, whereas refractory oral disease required rituximab to achieve remission, highlighting the need for individualized, multimodal therapy to achieve sustained disease control.
Mahlatse Cordelia Kgokolo, Lesedi Makgwethele Nevondo, Michaela Beetge, Razia A. G. Khammissa   +3 more
wiley   +1 more source

Use of rituximab in the treatment of pemphigus vulgaris in a juvenile patient

Przegląd Dermatologiczny
Introduction: Pemphigus vulgaris is a chronic autoimmune blistering disorder characterised by the production of autoantibodies against desmogleins, resulting in intraepithelial blister formation.
Hanna Róża Cisoń, Wojciech Baran, Rafał Białynicki-Birula   +2 more
doaj   +1 more source

Evaluation of the possible association between acantholysis and anti‐desmogleins 1 and 3 values in pemphigus vulgaris and pemphigus foliaceus

Journal of Cutaneous Immunology and Allergy, 2019
Objectives Acantholysis is the main pathologic finding in pemphigus, and its location has been historically used to distinguish the major subtypes of pemphigus vulgaris (PV) and pemphigus foliaceus (PF).
Maryam Mobarakabadi, Nazanin Rajai, Kambiz Kamyab, Kamran Balighi, Hamidreza Mahmoudi, Soheil Tavakolpour, Ali Nili, Azita Nikoo, Farnam Mohebi, Maryam Daneshpazhooh   +9 more
doaj   +1 more source

Integrated Immune, Epithelial and Lipid Pathways in NSAID‐Exacerbated Respiratory Disease

Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.
ABSTRACT NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic inflammatory disorder characterized by asthma, chronic rhinosinusitis with nasal polyps and respiratory reactions to cyclooxygenase‐1 inhibiting nonsteroidal anti‐inflammatory drugs (NSAID).
Piotr Szatkowski, Lucyna Mastalerz
wiley   +1 more source

Correlation of antibodies against desmogleins 1 and 3 with indirect immunofluorescence and disease status in a Greek population with pemphigus vulgaris

, 2013
Background The use of ELISA testing of antibodies to desmogleins 1 and 3 (anti-Dsg1 and anti-Dsg3) and indirect immunofluorescence (IIF) has been strongly supported for the serologic diagnosis of pemphigus. The purpose of this study was to correlate anti-
Avgerinou, G., Servitzoglou, M., Katsambas, A., Papafragkaki, D.-K., Arapaki, A., Stavropoulos, P.G., Markantoni, V., Nasiopoulou, A.   +7 more
core   +1 more source

Implications of normal and disordered remodeling dynamics of corneodesmosomes in stratum corneum

Dermatologica Sinica, 2015
Desmosomes and corneodesmosomes are the most important adhering junctions, providing strength for the epidermal sheet structure made of living keratinocytes and enucleated stratum corneum corneocytes, respectively.
Yasuo Kitajima
doaj   +1 more source

If pemphigus vulgaris IgG are the cause of acantholysis, new IgG-independent mechanisms are the concause.

, 2007
Pemphigus vulgaris (PV) is a disease of epidermal adhesion. Its pathogenesis is currently traced back to the action of autoantibodies against antigens located within the intercellular substance of keratinocytes, such as desmogleins and acetylcholine ...
Femiano, F, Gombos, F, CIRILLO N, Giovanni Maria Gaeta, Lanza, A, Michele Lanza, Felice Femiano, Cirillo, N, GAETA GM, LANZA, Michele, Nicola Cirillo, FEMIANO, Felice, Fernando Gombos, GOMBOS, Fernando, De Rosa, A, LANZA, Alessandro, DE ROSA, Alfredo, Lanza, M, Alfredo De Rosa, Alessandro Lanza, Gaeta, G M   +20 more
core   +1 more source

Visualisation by electron microscopy of the unique part of the cytoplasmic domain of a desmoglein, a cadherin-like protein of the desmosome type of cell junction [PDF]

, 1994
Part of the cytoplasmic domain of a human desmoglein, Dsgl, a cadherin-like protein found in desmosomes of epithelial cells, has been visualised by electron microscopy.
Rutman, A.J., Burdett, I.D.J., A.J. Rutman, Buxton, R.S., I.D.J. Burdett, R.S. Buxton   +5 more
core   +1 more source

Desmoglein autoimmunity in the pathogenesis of pemphigus

Autoimmunity, 2006
The most characteristic feature of pemphigus is a loss of cohesion between keratinocytes, resulting in formation of blisters and erosions on the mucosal membranes and the skin. Identification of circulating antibodies which bind to desmogleins (Dsg), transmembrane proteins involved in assembly of the desmosomes, led to the immediate realization that ...
openaire   +2 more sources

DSG2 (desmoglein 2) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on DSG2 (desmoglein 2), with data on DNA, on the protein encoded, and where the gene is implicated.
openaire   +2 more sources