Results 11 to 20 of about 104 (87)

Serologic Biomarkers in Pemphigus Monitoring: C-reactive Protein, Macrophage Migration Inhibitory Factor, and Prolactin Levels Versus Autoantibody Assays

Iranian Journal of Allergy, Asthma and Immunology, 2023
Evaluation and monitoring of pemphigus vulgaris (PV) typically involve autoantibody detection by enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescence (IIF).
Hossein Mortazavi, Vahide Saeidi, Kamran Balighi, Nafiseh Esmaeili, Amir Teimourpour, Maryam Daneshpazhooh, Shahin Hamzelou, Zahra Saffarian, Jafar Taghizadeh Fazli   +8 more
doaj   +1 more source

Autoantibodies other than anti-desmogleins in pemphigus vulgaris patients

Indian Journal of Dermatology, 2017
Background: Pemphigus vulgaris (PV) is an immunoglobulin G-mediated autoimmune bullous skin disease. Nonorgan-specific antibodies were detected in Tunisian and Brazilian pemphigus patients with different prevalence.
Marwah Adly Saleh, Hedayat Salem, Hoda El Azizy   +2 more
doaj   +1 more source

Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?

Cells, 2022
Pemphigus vulgaris is an autoimmune blistering disease of the epidermis, caused by autoantibodies against desmosomal proteins, mainly desmogleins 1 and 3, which induce an impairment of desmosomal adhesion and blister formation. Recent findings have shown
Anna Zakrzewicz, Celina Würth, Benedikt Beckert, Simon Feldhoff, Katrien Vanderheyden, Stian Foss, Jan Terje Andersen, Hans de Haard, Peter Verheesen, Vladimir Bobkov, Ritva Tikkanen   +10 more
doaj   +1 more source

Recurrence of Pemphigus Vulgaris after Bilateral Breast Irradiation: A Case Report and Review of the Literature

Case Reports in Oncology, 2021
Pemphigus is a serious and rare chronic bullous autoimmune disease. It is characterized by mucocutaneous erosions secondary to autoantibodies directed against desmogleins 1 and 3, proteins involved in intercellular adhesion mechanisms.
Camille Invernizzi, Victor Gaultier, Philippe Guilbert, Christelle Jouannaud, Anne-Laure Labrousse, Charles Marchand Crety   +5 more
doaj   +1 more source

Paraneoplastic pemphigus: a clinical, laboratorial, and therapeutic overview [PDF]

Anais Brasileiros de Dermatologia, 2019
: Paraneoplastic pemphigus is a rare and severe autoimmune blistering disease characterized by mucocutaneous lesions associated with benign and malignant neoplasms.
Celina Wakisaka Maruta, Denise Miyamoto, Valeria Aoki, Ricardo Gomes Ribeiro de Carvalho, Breno Medeiros Cunha, Claudia Giuli Santi   +5 more
doaj   +1 more source

Taiwanese dermatological association (TDA) consensus for the management of pemphigus

Journal of the Formosan Medical Association, 2023
Pemphigus is an uncommon but life-threatening autoimmune blistering disease characterized by the presence of antibodies against desmogleins. Without effective treatment, pemphigus can result in significant morbidity and mortality.
Chia-Yu Chu, Chih-Hung Lee, Hua-En Lee, Yung-Tsu Cho, Chao-Kai Hsu, Tom C. Chan, Song-Chou Hsieh, Kai-Che Wei   +7 more
doaj   +1 more source

Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer

BMC Cancer, 2008
Background In a previous report we have demonstrated that the chymotryptic-like serine protease kallikrein 7 (KLK7/hK7) is overexpressed in pancreatic cancer.
Haun Randy S, Hennings Leah, Ramani Vishnu C   +2 more
doaj   +1 more source

Autoimmune pemphigus: difficulties in diagnosis and the molecular mechanisms underlying the disease

Frontiers in Immunology
Recently recognised as a desmosomal disorder, autoimmune pemphigus remains severe in some of its forms, such as pemphigus vulgaris. This review is divided into four parts.
Olga Simionescu, Sorin Ioan Tudorache
doaj   +1 more source

Significado do epitope spreading na patogênese dos pênfigos vulgar e foliáceo Significance of epitope spreading in the pathogenesis of pemphigus vulgaris and foliaceus

Anais Brasileiros de Dermatologia, 2008
Os pênfigos são dermatoses bolhosas auto-imunes, em que há a produção de auto-anticorpos direcionados contra moléculas de adesão dos epitélios, levando à perda da coesão celular.
Valéria Aoki, Fernanda Lago, Márcia Harumi Yamazaki, Cláudia Giuli Santi, Celina Wakisaka Maruta   +4 more
doaj   +1 more source

Pemphigus—A Disease of Desmosome Dysfunction Caused by Multiple Mechanisms

Frontiers in Immunology, 2018
Pemphigus is a severe autoimmune-blistering disease of the skin and mucous membranes caused by autoantibodies reducing desmosomal adhesion between epithelial cells.
Volker Spindler, Jens Waschke
doaj   +1 more source