Results 51 to 60 of about 104 (87)

ECMO Support in Paraneoplastic Pemphigus With Respiratory Failure: A Case Report With Immune Cell Monitoring

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Paraneoplastic pemphigus (PNP) is a life‐threatening autoimmune blistering disease with a mortality rate of 70%–90%, driven largely by respiratory complications such as bronchiolitis obliterans. Managing respiratory failure in these patients remains exceptionally difficult.
Lu Li   +5 more
wiley   +1 more source

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 415-424, June 2026.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri   +2 more
wiley   +1 more source

Organoids: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li   +6 more
wiley   +1 more source

Use of rituximab in the treatment of pemphigus vulgaris in a juvenile patient

open access: yesPrzegląd Dermatologiczny
Introduction: Pemphigus vulgaris is a chronic autoimmune blistering disorder characterised by the production of autoantibodies against desmogleins, resulting in intraepithelial blister formation.
Hanna Róża Cisoń   +2 more
doaj   +1 more source

Deciphering the full spectrum of Castleman diseases based on a cohort of 700 patients in a western country

open access: yesBritish Journal of Haematology, Volume 208, Issue 6, Page 2036-2046, June 2026.
The spectrum of Castleman diseases has expanded over the past three decades. The phenotype of the diseases varies not only among the three major types but also according to the patient ancestry. Summary Under the Castleman disease (CD) eponym, three distinct diseases sharing common pathological features have been described over time.
Eric Oksenhendler   +4 more
wiley   +1 more source

Evaluation of the possible association between acantholysis and anti‐desmogleins 1 and 3 values in pemphigus vulgaris and pemphigus foliaceus

open access: yesJournal of Cutaneous Immunology and Allergy, 2019
Objectives Acantholysis is the main pathologic finding in pemphigus, and its location has been historically used to distinguish the major subtypes of pemphigus vulgaris (PV) and pemphigus foliaceus (PF).
Maryam Mobarakabadi   +9 more
doaj   +1 more source

Implications of normal and disordered remodeling dynamics of corneodesmosomes in stratum corneum

open access: yesDermatologica Sinica, 2015
Desmosomes and corneodesmosomes are the most important adhering junctions, providing strength for the epidermal sheet structure made of living keratinocytes and enucleated stratum corneum corneocytes, respectively.
Yasuo Kitajima
doaj   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

open access: yesChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci   +5 more
wiley   +1 more source

Paraneoplastic pemphigus associated with chronic lymphocytic leukemia: a case report

open access: yesJournal of Medical Case Reports, 2018
Background Paraneoplastic pemphigus is a rare multiorgan disease of autoimmune causes, usually triggered by neoplasias, mainly of lymphoproliferative origin, such as leukemia and lymphoma.
Richard Lucas Konichi-Dias   +3 more
doaj   +1 more source

Circulating Antibodies Against DSG1 and DSG3 in Patients with Oral Lichen Planus: A Scoping Review

open access: yesAntibodies
Oral Lichen Planus (OLP) is a chronic autoimmune disease with potential overlap with Pemphigus Vulgaris (PV), particularly in erosive forms. Desmoglein 1 and 3 are transmembrane glycoproteins of desmosomes, typically involved in PV.
Domenico De Falco   +5 more
doaj   +1 more source

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