Results 111 to 120 of about 12,510 (224)

Diversity of Intercellular Communication Modes: A Cancer Biology Perspective

Cells
From the moment a cell is on the path to malignant transformation, its interaction with other cells from the microenvironment becomes altered. The flow of molecular information is at the heart of the cellular and systemic fate in tumors, and various ...
Thanzeela Ebrahim, Abdul Shukkur Ebrahim, Mustapha Kandouz   +2 more
doaj   +1 more source

The hidden science of haptics: A pedagogical review of tactile evaluation in cosmetics

International Journal of Cosmetic Science, Volume 48, Issue 3, Page 600-634, June 2026.
This review explores the physiological basis of tactile perception and critically examines classical and emerging sensory methods used in cosmetics, advocating for broader methodological integration and recognition of sensory analysis in the field. Abstract Sensory analysis is a cornerstone of cosmetic development, yet remains underrepresented in peer ...
Morgane Postec, Daria Terescenco, Ecaterina Gore   +2 more
wiley   +1 more source

Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype

, 2021
The role that mechanical forces play in shaping the structure and function of the heart is critical to understanding heart formation and the etiology of disease but is challenging to study in patients.
Hoes, M.F., Bomer, N., Bolling, M.C., Vermeer, M.C.S.C., Duffy, R.M., Palchesko, R.N., Boer, R.A. de, Feinberg, A.W., Kalmykov, A., Volkers, L., Pijnappels, D.A., Jongbloed, J.D.H., Suurmeijer, A.J.H., Bliley, J.M., Shiwarski, D.J., Kramer, D., Coffin, B., Tashman, J.W., Meer, P. van der, Lee, A., Teplenin, A.S., Sun, Y., Batalov, I.   +22 more
core   +1 more source

Dsg2 ectodomain organization increases throughout desmosome assembly

Cell Adhesion & Migration
Desmosomes are intercellular junctions that regulate mechanical integrity in epithelia and cardiac muscle. Dynamic desmosome remodeling is essential for wound healing and development, yet the mechanisms governing junction assembly remain elusive.
William F. Dean, Rose M. Albert, Tomasz J. Nawara, Melanie Ubil, Reena R. Beggs, Alexa L. Mattheyses   +5 more
doaj   +1 more source

Desmosomes and disease.

Histology and histopathology, 1997
Considerable progress has been made in our knowledge of desmosomes and their components. Molecular cloning of the desmosomal glycoproteins has established that desmoglein 1 and desmoglein 3 are targets for autoantibodies in the blistering diseases pemphigus foliaceus and pemphigus vulgaris respectively.
openaire   +2 more sources

Calcium-independent desmosome adhesion : acquisition, maintenance and modulation

, 1994
Desmosomal adhesion is known to be calcium dependent and desmosomal glycoproteins belong to the cadherin superfamily of adhesion molecules. Thus, MDCK cells in short term cultures lose cell-cell adhesion when extracellular calcium concentrations are ...
Lloyd, Susan
core  

The role of desmosomes in carcinogenesis

OncoTargets and Therapy, 2017
Desmosomes, which are intercellular adhesive complexes, are essential for the maintenance of epithelial homeostasis. They are located at the cell membrane, where they act as anchors for intermediate filaments. Downregulation of desmosome proteins in various cancers promotes tumor progression.
Guangxin Zhou, Linlin Yang, Ashley Gray, Amit Kumar Srivastava, Cuiping Li, Gongwen Zhang, Tiantian Cui   +6 more
openaire   +4 more sources

The Biology of the Desmosome-Like Junction

, 2011
Mammalian spermatogenesis, a complex process that involves the movement of developing germ cells across the seminiferous epithelium, entails extensive restructuring of Sertoli-Sertoli and Sertoli-germ cell junctions.
Pearl P.Y. Lie, C. Yan Cheng, Dolores D. Mruk, Cheng, C. Yan, Lie, Pearl P.Y., Mruk, Dolores D.   +5 more
core   +1 more source

A Paradigm Shift: Arrhythmogenic Cardiomyopathy Is an Inflammatory Disease

Cells
Arrhythmogenic cardiomyopathy (ACM) is a genetic myocardial disorder marked by progressive cardiomyocyte loss, fibro-fatty replacement, ventricular arrhythmias, and risk of sudden cardiac death.
Gallage H. D. N. Ariyaratne, Andrea Villatore, Giovanni Peretto, Stephen P. Chelko   +3 more
doaj   +1 more source

USING THE FROG EPIDERMIS TO UNCOVER DESMOSOME FUNCTION AND REGULATION IN THE DEVELOPING EMBRYO

, 2018
The desmosome is one of the major cell adhesion junctions found in the epithelia, heart, and hair follicle. Described as a “rivet” that hold cells together, it provides these tissues with the integrity to withstand the tremendous forces they face in ...
Bharathan, Navaneetha Krishnan
core   +1 more source