Results 111 to 120 of about 13,148 (221)

Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype (Software)

, 2021
These are the MATLAB scripts used to analyze (1) actin alignment in immunofluorescrently labeled images of engineered cardiac tissues, (2) calcium dynamics in engineered cardiac tissues, and (3) contractility of dynamic engineered heart tissues (dyn-EHTs)
Feinberg, Adam W., Tashman, Joshua W., Batalov, Ivan, Shiwarski, Daniel J., Bliley, Jacqueline M.   +4 more
core   +1 more source

Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability

, 2003
Ablation of the desmosomal plaque component plakophilin 1 underlies the autosomal recessive genodermatosis, skin fragility-ectodermal dysplasia syndrome (OMIM 604536).
Michael G. Stone, John F. Marshall, Andrew P. South, Hart, I R, Purkis, Patricia E., Stone, Michael G., Ian R. Hart, Dopping-Hepenstal, P J C, Leigh, Irene M., Patricia E. Purkis, McGrath, John A., McGrath, J A, John A. McGrath, Eady, R A J, Marshall, John F., South, A P, Marshall, J F, Hong Wan, South, Andrew P., Wan, Hong, Robin A. J. Eady, Stone, M G, Patricia J. C. Dopping-Hepenstal, Wan, H, Leigh, I M, Irene M. Leigh, Eady, Robin A. J., Dopping-Hepenstal, Patricia J. C., Hart, Ian R., Purkis, P E   +29 more
core   +1 more source

Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin [PDF]

, 1997
The cornified envelope is a layer of transglutaminase cross-linked protein that is assembled under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Christiana Ruhrberg, Hajibagheri, MAN, Parry, DAD, Watt, FM, Ruhrberg, C, M.A. Nasser Hajibagheri, David A.D. Parry, Fiona M. Watt   +7 more
core   +1 more source

S100A11 is involved in the progression of colorectal cancer through the desmosome-catenin-TCF signaling pathway [PDF]

Compiling evidence has indicated that S100A11 expression at high levels is closely associated with various cancer species. Consistent with the results reported elsewhere, we have also revealed that S100A11 is highly expressed in squamous cell carcinoma ...
Sakaguchi, Masakiyo, Yamamoto, Ken-ichi, Murata, Hitoshi, Mizuta, Naoko, Zhou, Jin, Kinoshita, Rie, Tomonobu, Nahoko, Yamakawa, Atsuko   +7 more
core   +1 more source

Pemphigus—A Disease of Desmosome Dysfunction Caused by Multiple Mechanisms [PDF]

, 2018
Pemphigus is a severe autoimmune-blistering disease of the skin and mucous membranes caused by autoantibodies reducing desmosomal adhesion between epithelial cells.
Jens Waschke, Waschke, Jens, Volker Spindler, Spindler, Volker   +3 more
core   +1 more source

Desmosomes in pemphigus vegetans

Acta Dermato-Venereologica, 1981
Desmosomes of a patient suffering from pemphigus vegetans were studied by electron microscopy and analysed by morphometry, The desmosomes were fewer in the patient´s skin than in healthy individuals. The desmosomes of the patient were thin and short, showing pathological ultrastructures, viz.
T, Higashida, H, Hino, T, Kobayasi
openaire   +2 more sources

PENETRATION TEST OF CAFFEINE IN ETHOSOME AND DESMOSOME GEL USING AN IN VITRO METHOD [PDF]

, 2017
Objectives: Caffeine has many functions including its use in the field of cosmetics. Nonetheless, the percutaneous absorption of caffeine is very low(9%), and the penetration of a substance such as caffeine in the skin is not desirable.
Puteri, Alvina Wijaya, Ernysagita, Ernysagita, Ernysagita Ernysagita, Iskandarsyah, Iskandarsyah, Iskandarsyah Iskandarsyah, Alvina Wijaya Puteri   +5 more
core   +1 more source

The Diagnostic and Prognostic Value of the 12-Lead ECG in Arrhythmogenic Left Ventricular Cardiomyopathy

JACC: Advances
Background: Electrocardiographic findings in arrhythmogenic left ventricular cardiomyopathy (ALVC) have been limited to small studies. Objectives: The authors aimed to analyze the electrocardiogram (ECG) characteristics of ALVC, to correlate ECG with ...
Leonardo Calò, MD, Cinzia Crescenzi, MD, Andrea Di Marco, MD, PhD, Francesca Fanisio, MD, Fabiana Romeo, MD, Alessio Gargaro, MSc, Annamaria Martino, MD, PhD, Chiara Cappelletto, MD, Marco Merlo, MD, Mattia Targetti, MD, Elisabetta Toso, MD, Federica Toto, MD, Maria Beatrice Musumeci, MD, Giacomo Tini, MD, Michele Ciabatti, MD, Matteo Stefanini, MD, Stefano Canestrelli, MD, Elisa Fedele, MD, Chiara Lanzillo, MD, PhD, Armando Fusco, MD, PhD, Federica Carla Sangiuolo, MD, PhD, Cinzia Radesich, MD, Maria Perotto, MD, Maurizio Pieroni, MD, Ruggiero Mango, MD, PhD, Alessio Gasperetti, MD, PhD, Camillo Autore, MD, Michela Casella, MD, PhD, Antonio Dello Russo, MD, PhD, Davide Stolfo, MD, PhD, Mikael Laredo, MD, PhD, Estelle Gandjbakhch, MD, PhD, Maddalena Graziosi, MD, PhD, Elena Biagini, MD, PhD, Costantina Catalano, MD, Ludovica Barile, MD, Fabrizio Drago, MD, Marianna Cicenia, MD, Anwar Baban, MD, PhD, Gemma Pelargonio, MD, PhD, Maria Lucia Narducci, MD, Federica Re, MD, Giovanni Peretto, MD, Elena Paiotti, MD, Carles Diez Lopez, MD, Iacopo Olivotto, MD, Fiorenzo Gaita, MD, Gianfranco Sinagra, MD, Giuseppe Novelli, MD, PhD   +48 more
doaj   +1 more source

Desmosomes and disease.

Histology and histopathology, 1997
Considerable progress has been made in our knowledge of desmosomes and their components. Molecular cloning of the desmosomal glycoproteins has established that desmoglein 1 and desmoglein 3 are targets for autoantibodies in the blistering diseases pemphigus foliaceus and pemphigus vulgaris respectively.
openaire   +2 more sources

The role of desmosomes in carcinogenesis

OncoTargets and Therapy, 2017
Desmosomes, which are intercellular adhesive complexes, are essential for the maintenance of epithelial homeostasis. They are located at the cell membrane, where they act as anchors for intermediate filaments. Downregulation of desmosome proteins in various cancers promotes tumor progression.
Guangxin Zhou, Linlin Yang, Ashley Gray, Amit Kumar Srivastava, Cuiping Li, Gongwen Zhang, Tiantian Cui   +6 more
openaire   +4 more sources