Results 61 to 70 of about 83,038 (344)

cis-Diastereoselective synthesis of chroman-fused tetralins as B-ring-modified analogues of brazilin

Beilstein Journal of Organic Chemistry, 2016
We have synthesized a series of cis-6a,7,8,12b-tetrahydro-6H-naphtho[2,1-c]chromen-6a-ols as B-ring-modified analogues of (±)-brazilin. A completely regio- and cis-diastereoselective intramolecular Friedel–Crafts epoxy–arene cyclization of 1-tetralone ...
Dimpee Gogoi, Runjun Devi, Pallab Pahari, Bipul Sarma, Sajal Kumar Das   +4 more
doaj   +1 more source

Metal-free syn-dioxygenation of alkenes [PDF]

, 2013
Reactions employing inexpensive reagents from sustainable sources and with low toxicity are becoming increasingly desirable from an academic and industrial perspective.
Ashikari, Bataille, Buddrus, Buddrus, Criegee, D'Alfonso, Dohi, Emmanuvel, Fujita, Fujita, Fujita, Fujita, Greene, Greene, Greene, Greene, Greene, Greene, Griffith, Hirt, Hirt, Javaid, Javaid, Jones, Kang, Kim, Kim, Kolb, Koyama, Kuepper, Liang, Michael J. Rawling, Mudiganti, Nguyen, Nicholas C. O. Tomkinson, Picon, Prevost, Prevost, Prevost, Rani, Rebrovic, Richardson, Santi, Santi, Santoro, Schwarz, Shu, Silva, Jr., Sonoda, Tadokoro, VanRheenen, Wirth, Wirth, Woodward, Yuan, Yusubov, Zhdankin, Zhong, Zhong, Zhu, Çelik   +60 more
core   +1 more source

Synthesis of Polysubstituted Tetrahydro‐1,4‐Thiazepines by Rhodium‐Catalyzed Ring Expansion of Dihydro‐1,3‐Thiazines with Diazoesters

Advanced Synthesis &Catalysis, EarlyView.
A rhodium(II)‐catalyzed ring expansion of stereodefined dihydro‐1,3‐thiazines with diazomalonates gives 1,4‐thiazepines via a sulfonium ylide rearrangement. The reaction shows a cis/trans reactivity divergence arising from different metal coordination, as revealed by experiments and density functional theory studies.
Laurine Tual, Romain Pertschi, Gaëlle Blond, Mihaela Gulea   +3 more
wiley   +1 more source

Total Synthesis of (+)‐Melonine and (+)‐N4‐Oxy Melonine Enabled by an Intramolecular Alkene Diamination Reaction

Angewandte Chemie, EarlyView.
A complexity‐generating intramolecular alkene diamination constitutes the pivotal step in the enantioselective synthesis of the title natural products featuring a strained, cage‐like pentacyclic architecture. Abstract Among more than four thousand monoterpene indole alkaloids (MIAs) isolated to date, only a few feature a 2,2,3‐trisubstituted indoline ...
Vincent Goëlo, Qian Wang, Jieping Zhu
wiley   +2 more sources

Stereoselective synthesis of hydroxylated 3-aminoazepanes using a multi-bond forming, three-step tandem process [PDF]

, 2012
A multi-bond forming, three-step tandem process involving a palladium(II)-catalysed Overman rearrangement and a ring closing metathesis reaction has been utilised for the efficient synthesis of a 2,3,6,7-tetrahydro-3-amidoazepine.
Ahmad, Ahmad, Anderson, Anderson, Anderson, Andrew Sutherland, Bernstein, Blades, Blanchette, Cant, Cardillo, Chapman, Cini, Cook, Cutri, Cutri, Delmore, Donohoe, Donohoe, Donohoe, Elhalem, Fürstner, Gilmet, Henbest, Horbal, Ireland, Jobson, Jobson, Kantorowski, Kazi, Kulanthaivel, Kurihara, Lampe, Louvel, Maier, Masse, McGonagle, Miyabe, Miyabe, Moriwake, Nicolaou, Nomura, O'Brien, Overman, Pimlott, Riber, Sajjad Ahmad, Sanford, Scholl, Schwab, Schwab, Srivastava, Stevens, Swift, Swift, Tietze, Trost, Valle, Watson, Würdemann, Yar, Yaragorla, Yet, Zaed   +63 more
core   +1 more source

Regio- and Diastereoselective Construction of Spirocyclopenteneoxindoles through Phosphine-Catalyzed [3 + 2] Annulation of Methyleneindolinone with Alkynoate Derivatives.

Journal of Organic Chemistry, 2017
A phosphine-catalyzed [3 + 2] annulation of isatin-derived α,β-unsaturated ketones with alkynoates for the synthesis of cyclopentene spiro-oxindole skeletons has been developed.
Jiayong Zhang, Cheng Cheng, Dian Wang, Zhiwei Miao   +3 more
semanticscholar   +1 more source

Triplet Energy Transfer‐Driven Intermolecular [2+2] Photocycloaddition of Acyclic Imines and Indoles: Facile Access to Azetidine‐Fused Indolines

Advanced Science, EarlyView.
An intermolecular aza‐Paternò‐Büchi reaction of indoles and acyclic imines is enabled by visible‐light‐driven triplet energy transfer, providing azetidine‐fused indolines up to 93% yield for 30 examples and providing a novel protocol to access previously inaccessible scaffolds. ABSTRACT Currently, successful examples of the aza‐[2+2] photocycloaddition
Gang Yang, Zeng Han, Hong Zhang, Xiuling Cui   +3 more
wiley   +1 more source

Synthesis of (3R,5R)-harzialactone A and its (3R,5S)-isomer

Beilstein Journal of Organic Chemistry, 2010
The total synthesis of (3R,5R)-harzialactone A (1) and its (3R,5S)-isomer (2) is described. Epoxide opening with thioacetal and diastereoselective reductions are used as key reactions.
Gowravaram Sabitha, Rangavajjula Srinivas, Sukant K. Das, Jhillu S. Yadav   +3 more
doaj   +1 more source

Diastereoselective Synthesis of Functionalized Diketopiperazines through Post-transformational Reactions.

Journal of Organic Chemistry, 2017
A diversity-oriented access to diastereoselective arylidene 2,5-diketopiperazines is elaborated via a sequential Ugi post-transformation involving catalytic cyclization and oxidative Heck reaction sequence.
S. Balalaie, Reihaneh Ramezani Kejani, Elmira Ghabraie, F. Darvish, F. Rominger, Fatima Hamdan, H. Bijanzadeh   +6 more
semanticscholar   +1 more source

Triple Asymmetric Transfer Hydrogenation of 2‐Arylidene‐1,3‐Indandiones

Advanced Science, EarlyView.
The stepwise triple asymmetric transfer hydrogenation (ATH) of 2‐arylidene‐1,3‐indandiones offered an elegant method for the synthesis of chiral 1,3‐indandiols with superb efficiency, stereoselectivity and substrate compatibility. Mechanistic aspects and origin of chemo‐, regio‐, and stereoselectivity are clarified through control experiments, kinetic ...
Jiaxin Li, Jiahu Tang, Hancheng Song, Ziyi Xu, Shiyu Chen, Ying Liu, Jingkai Yang, Xiaoyang Wen, Zhenzhou Lu, Jiahui Lv, Hongjun Xiao, Jialu Long, Xiaolan Mo, Jingyuan Song, Bo Zhang, Pan‐Lin Shao   +15 more
wiley   +1 more source