Results 11 to 20 of about 28,160 (153)

Pattern formation in Dictyostelium [PDF]

Cold Spring Harbor Monograph Archive, 1984
INTRODUCTION Upon starvation, amoebae of the cellular slime mold Dictyostelium undergo a program of development in which individual cells aggregate to form a multicellular slug and, subsequently, a fruiting body consisting of stalk cells and spores (Loomis 1982).
MacWilliams, H., David, Charles N.
openaire   +5 more sources

Stochastic noise and synchronisation during Dictyostelium aggregation make cAMP oscillations robust [PDF]

, 2007
The molecular network, which underlies the oscillations in the concentration of adenosine 3′, 5′-cyclic monophosphate (cAMP) during the aggregation phase of starvation-induced development in Dictyostelium discoideum, achieves remarkable levels of robust ...
Bates, Declan, Heslop-Harrison, Pat, Kim, Jongrae, Postlethwaite, Ian   +3 more
core   +17 more sources

An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba dictyostelium discoideum [PDF]

, 2014
Mutations in either of two presenilin genes can cause familial Alzheimer's disease. Presenilins have both proteolysis-dependent functions, as components of the γ-secretase complex, and proteolysis-independent functions in signalling.
Ahn, Allan, Berridge, Boeckeler, Calahorro, Chang, Chávez-Gutiérrez, Coen, De Strooper, De Strooper, De Strooper, Donoviel, Edbauer, Eichinger, Faix, Feng, Fluhrer, Francione, Garcia, Haass, Harwood, Herreman, Hooper, Huppert, Janetopoulos, Kang, Kang, Khandelwal, Kim, Kumar, Li, Livak, Loomis, Ludtmann, McMains, Myre, Müller, Müller-Taubenberger, Parks, Rambaut, Rambaut, Ronquist, Rozen, Saxe, Schaeffer, Shen, Terbach, Tesco, Tu, Twomey, van Tijn, Veltman, Veltman, Walter, Wang, Williams, Williams, Williams, Wolfe, Yamasaki   +59 more
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The Cell Density Factor CMF Regulates the Chemoattractant Receptor cAR1 in Dictyostelium [PDF]

, 1996
Starving Dictyostelium cells aggregate by chemotaxis to cAMP when a secreted protein called conditioned medium factor (CMF) reaches a threshold concentration.
Bishop, John D.,, Gomer, Richard H.,, Haastert, Peter J.M. van,   +2 more
core   +4 more sources

Moving the Research Forward: The Best of British Biology Using the Tractable Model System Dictyostelium discoideum

Cells, 2021
The social amoeba Dictyostelium discoideum provides an excellent model for research across a broad range of disciplines within biology. The organism diverged from the plant, yeast, fungi and animal kingdoms around 1 billion years ago but retains common ...
Robin S. B. Williams, Jonathan R. Chubb, Robert Insall, Jason S. King, Catherine J. Pears, Elinor Thompson, Cornelis J. Weijer   +6 more
doaj   +1 more source

The annexins of Dictyostelium

European Journal of Cell Biology, 2006
Annexins are a highly conserved ubiquitous family of Ca2+- and phospholipid-binding proteins present in nearly all eukaryotic cells. Analysis of the Dictyostelium genome revealed the presence of two annexin genes, the annexin C1 gene (nxnA) giving rise to two isoforms of 47 and 51 kDa (previously synexin), and the annexin C2 gene (nxnB) coding for a 56-
Rolf Müller, Marija Marko, Yogikala Prabhu, Angelika A. Noegel, Michael Schleicher, Rosemarie Blau-Wasser   +5 more
openaire   +3 more sources

The role of the cortical cytoskeleton [PDF]

, 1996
We generated Dictyostelium double mutants lacking the two F-actin crosslinking proteins alpha-actinin and gelation factor by inactivating the corresponding genes via homologous recombination.
Albrecht, Richard, Bozzaro, Salvatore, Köppel, Bernd, Noegel, Angelika A., Peracino, Barbara, Rivero, Francisco, Schleicher, Michael, Siegert, Florian, Weijer, Cornelis J.   +8 more
core   +1 more source

Visualization of c-di-GMP in multicellular Dictyostelium stages

Frontiers in Cell and Developmental Biology, 2023
The bacterial signaling molecule cyclic diguanosine monophosphate (c-di-GMP) is only synthesized and utilized by the cellular slime mold Dictyostelium discoideum among eukaryotes.
Hayato Ide, Yukihisa Hayashida, Yusuke V. Morimoto, Yusuke V. Morimoto   +3 more
doaj   +1 more source

Triparental inheritance in Dictyostelium [PDF]

Proceedings of the National Academy of Sciences, 2018
Sex promotes the recombination and reassortment of genetic material and is prevalent across eukaryotes, although our knowledge of the molecular details of sexual inheritance is scant in several major lineages. In social amoebae, sex involves a promiscuous mixing of cytoplasm before zygotes consume the majority of cells, but for technical ...
Gareth Bloomfield, Peggy Paschke, Marina Okamoto, Tim J. Stevens, Hideko Urushihara   +4 more
openaire   +4 more sources

Cooperative cell motility during tandem locomotion of amoeboid cells. [PDF]

, 2016
Streams of migratory cells are initiated by the formation of tandem pairs of cells connected head to tail to which other cells subsequently adhere. The mechanisms regulating the transition from single to streaming cell migration remain elusive, although ...
Bastounis, Effie, del Álamo, Juan C, Firtel, Richard A, Lasheras, Juan C, Álvarez-González, Begoña   +4 more
core   +2 more sources