Identification of imprinting regulators at the Meg3 differentially methylated region [PDF]
Genomics, 2012 Genomic imprinting at the Delta-like 1 (Dlk1) - Maternally expressed gene 3 (Meg3) locus is regulated by the Meg3 differentially methylated region (DMR), but the mechanism by which this DMR acts is unknown.
Jennifer V Schmidt
exaly +12 more sources
Genome-Wide Differentially Methylated Region Analysis to Reveal Epigenetic Differences of Articular Cartilage in Kashin–Beck Disease and Osteoarthritis [PDF]
Frontiers in Cell and Developmental Biology, 2021 Kashin–Beck disease (KBD) is a degenerative osteoarticular disorder, and displays the significant differences with osteoarthritis (OA) regarding the etiology and molecular changes in articular cartilage.
Yan Wen, Xiong Guo
exaly +3 more sources
Placental maternally expressed gene 3 differentially methylated region methylation profile is associated with maternal glucose concentration and newborn birthweight [PDF]
Journal of Diabetes Investigation, 2021 Aims/Introduction Emerging evidence shows that epigenetic modifications occurring during fetal development in response to intrauterine exposures could be one of the mechanisms involved in the early determinants of adult metabolic disorders.
Cheng Chen +9 more
doaj +3 more sources
Identification of differentially methylated region (DMR) networks associated with progression of nonalcoholic fatty liver disease [PDF]
Scientific Reports, 2018 The progression of nonalcoholic fatty liver disease (NAFLD) is affected by epigenetics. We performed differentially methylated region (DMR) and co-methylation analyses to identify DMR networks associated with the progression of NAFLD.
Kento Imajo +2 more
exaly +3 more sources
Sequence variants identification at the KCNQ1OT1:TSS differentially Methylated region in isolated omphalocele cases [PDF]
BMC Medical Genetics, 2017 Background Omphalocele is a congenital midline ventral body wall defect that can exist as isolated malformation or as part of a syndrome. It can be considered one of the major and most frequent clinical manifestation of Beckwith-Wiedemann Syndrome (BWS ...
Maria Francesca Bedeschi +14 more
doaj +3 more sources
Low maternal adherence to a Mediterranean diet is associated with increase in methylation at the MEG3-IG differentially methylated region in female infants. [PDF]
Environ Epigenet, 2017 Diet is dictated by the surrounding environment, as food access and availability may change depending on where one lives. Maternal diet during pregnancy is an important part of the in utero environment, and may affect the epigenome.
Gonzalez-Nahm S +6 more
europepmc +2 more sources
A differentially methylated region of the ZmCCT10 promoter affects flowering time in hybrid maize
Crop Journal, 2023 Flowering time (FT) is a key maize domestication trait, variation in which allows maize to grow in a wide range of latitudes. Although previous studies have investigated the genetic control of FT-related traits per se, few studies of FT hybrid ...
Zhiqiang Zhou +9 more
doaj +2 more sources
Genome Biology, 2021 Background DNA methylation dynamics in the brain are associated with normal development and neuropsychiatric disease and differ across functionally distinct brain regions.
Lindsay F. Rizzardi +11 more
doaj +2 more sources
Epigenetics, 2023 Differentially methylated regions (DMRs) are genomic regions with methylation patterns across multiple CpG sites that are associated with a phenotype.
Mark W Miller +2 more
exaly +2 more sources
DMRFusion: A differentially methylated region detection tool based on the ranked fusion method
Genomics, 2018 DNA methylation is an important epigenetic modification involved in many biological processes and diseases. Computational analysis of differentially methylated regions (DMRs) could explore the underlying reasons of methylation.
Mohammad Amin Kerachian +2 more
exaly +2 more sources