Results 61 to 70 of about 82,227 (164)

Cyclic Diguanylate Signaling Proteins Control Intracellular Growth of Legionella pneumophila

mBio, 2011
Proteins that metabolize or bind the nucleotide second messenger cyclic diguanylate regulate a wide variety of important processes in bacteria. These processes include motility, biofilm formation, cell division, differentiation, and virulence.
Assaf Levi, Marc Folcher, Urs Jenal, Howard A. Shuman   +3 more
doaj   +1 more source

Population Genomics of Microbial Biostalactites: Non-recombinogenic Genome Islands and Microdiversification by Transposons

Frontiers in Microbiology, 2022
Intrapopulation genetic variability in prokaryotes is receiving increasing attention thanks to improving sequencing methods; however, the ability to distinguish intrapopulation variability from species clusters or initial stages of gene flow barrier ...
Kateřina Burkartová, Jiří Dresler, Jakub Rídl, Jakub Rídl, Lukáš Falteisek   +4 more
doaj   +1 more source

High levels of cyclic di-GMP in Klebsiella pneumoniae attenuate virulence in the lung [PDF]

, 2018
The bacterial second messenger bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) has been shown to influence the expression of virulence factors in certain pathogenic bacteria, but little is known about its activity in the increasingly antibiotic-resistant ...
Hunstad, David A, Rosen, David A, Twentyman, Joy   +2 more
core   +2 more sources

Functional characterization of multiple PAS domain-containing diguanylate cyclases in Synechocystis sp. PCC 6803.

Microbiology, 2020
Bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) is a second messenger known to control a variety of bacterial processes. The model cyanobacterium, Synechocystis sp.
K. Ishikawa, Chihiro Chubachi, S. Tochigi, Naomi Hoshi, S. Kojima, M. Hyodo, Y. Hayakawa, T. Furuta, K. Kera, N. Uozumi   +9 more
semanticscholar   +1 more source

Subcellular Clustering of the Phosphorylated WspR Response Regulator Protein Stimulates Its Diguanylate Cyclase Activity

mBio, 2013
WspR is a hybrid response regulator-diguanylate cyclase that is phosphorylated by the Wsp signal transduction complex in response to growth of Pseudomonas aeruginosa on surfaces.
Varisa Huangyutitham, Zehra Tüzün Güvener, Caroline S. Harwood   +2 more
doaj   +1 more source

Surface sensing for biofilm formation in Pseudomonas aeruginosa [PDF]

, 2017
YesAggregating and forming biofilms on biotic or abiotic surfaces are ubiquitous bacterial behaviors under various conditions. In clinical settings, persistent presence of biofilms increases the risks of healthcare-associated infections and imposes ...
Alexander, Ali-Ahmad, Alm, Baker, Baraquet, Baraquet, Barken, Belete, Bernier, Bhagirath, Breidenstein, Buensuceso, Caiazza, Chambonnier, Chua, Crouzet, Davies, De, Dötsch, Fata Moradali, Flemming, Fulcher, Galperin, Guilbaud, Gupta, Gupta, Güvener, Hancock, Heacock-Kang, Heiniger, Hengge, Hickman, Hickman, Hook, Hook, Huangyutitham, Irie, Jain, Johnson, Jones, Kanack, Kong, Kuchma, Kuchma, Kuchma, Kulasekara, Lapouge, Lee, Leighton, Li, Liao, Lin Chua, Luo, McCarter, Merighi, Merritt, Merritt, Mesaros, Mikkelsen, Monds, Moradali, Moscoso, Moscoso, Nadal Jimenez, Oglesby, Olsen, Orans, Patell, Percival, Persat, Poole, Rao, Ribbe, Rodesney, Romling, Rosenthal, Russotto, Siryaporn, Smith, Stewart, Su, Tuson, Ueda, Ueda, Vakulskas, Valentini, van Schaik, Wei, Whitchurch, Whitchurch, Winsor, Wolfgang, Wood, Wood, Yu   +94 more
core   +2 more sources

Differential regulation of c-di-GMP metabolic enzymes by environmental signals modulates biofilm formation in Yersinia pestis

Frontiers in Microbiology, 2016
Cyclic diguanylate (c-di-GMP) is essential for Yersinia pestis biofilm formation, which is important for flea-borne blockage-dependent plague transmission.
Gai-Xian eRen, Sai eFan, Xiao-Peng eGuo, Shiyun eChen, Yi-Cheng eSun   +4 more
doaj   +1 more source

Allosteric control of cyclic di-GMP signaling [PDF]

, 2006
Cyclic di-guanosine monophosphate is a bacterial second messenger that has been implicated in biofilm formation, antibiotic resistance, and persistence of pathogenic bacteria in their animal host.
Christen, B., Christen, M., Folcher, M., Jenal, U., Jenoe, P., Meuwly, M., Paul, R., Schmid, F.   +7 more
core   +1 more source

Phosphorylation-independent regulation of the diguanylate cyclase WspR.

PLoS Biology, 2008
Environmental signals that trigger bacterial pathogenesis and biofilm formation are mediated by changes in the level of cyclic dimeric guanosine monophosphate (c-di-GMP), a unique eubacterial second messenger.
Nabanita De, Michelle Pirruccello, Petya Violinova Krasteva, Narae Bae, Rahul Veera Raghavan, Holger Sondermann   +5 more
doaj   +1 more source

Cellular levels and binding of c-di-GMP control subcellular localization and activity of the Vibrio cholerae transcriptional regulator VpsT. [PDF]

PLoS Pathogens, 2012
The second messenger, cyclic diguanylate (c-di-GMP), regulates diverse cellular processes in bacteria. C-di-GMP is produced by diguanylate cyclases (DGCs), degraded by phosphodiesterases (PDEs), and receptors couple c-di-GMP production to cellular ...
Nicholas J Shikuma, Jiunn C N Fong, Fitnat H Yildiz   +2 more
doaj   +1 more source