Results 91 to 100 of about 20,507 (274)

Calcium channel blockers revisited [PDF]

open access: yes, 2002
published_or_final_versio
Cheung, BMY, Kumana, CR
core  

Ülevaade kaltsiumikanali antagonistide toimest endoteelile [PDF]

open access: yes, 2003
Kahjustunud endoteeli funktsioon on hüpertensiooni oluliseks riskiteguriks ja kliinilist kulgu määravaks faktoriks, mille mõjutamise kaudu on võimalik vähendada haigestumust ning suremust kardiovaskulaarsüsteemi haigustesse.
Kals, Jaak   +4 more
core   +2 more sources

Spotlight commentary—Insulin therapy: Future directions

open access: yes
British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 351-353, February 2026.
Ana Deškin   +4 more
wiley   +1 more source

Ringspannungs‐vermittelte Aktivierung von Pyridinen durch einen gesättigten BSi2‐Ring

open access: yesAngewandte Chemie, Volume 138, Issue 1, 2 January 2026.
Wir berichten über ein stark gespanntes Boratadisiliran mit dem bisher nicht zugänglichen anionischen BSi2‐Ringmotiv. Die Spaltung der S–Si‐Bindung während der Reaktionen mit Pyridinderivate aktiviert diese auf drei verschiedene Arten: (1) Bei Pyridin selbst erfolgt eine selektive ortho‐CH‐Aktivierung und ein gleichzeitiger Wasserstofftransfer zu einem
Nasrina Parvin   +5 more
wiley   +1 more source

Ring Strain‐Promoted Activation of Pyridines by a Saturated BSi2 Cycle

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 1, 2 January 2026.
We report a highly strained boratadisilirane with the elusive anionic BSi2 ring motif. Cleavage of the Si─Si bond during reactions with pyridine derivatives activates them in three different ways: 1) for pyridine itself selective ortho‐CH activation and concomitant hydrogen transfer to a second pyridine molecule occurs, 2) with dimethylaminopyridine ...
Nasrina Parvin   +5 more
wiley   +1 more source

A multifaceted approach for the development of novel Hantzsch 1,4-dihydropyridines as anticancer agents: Rational design, parallel synthesis, analysis, cytotoxicity and EGFR/HER2 inhibition studies

open access: yesResults in Chemistry
Dihydropyridines (DHPs) exhibit a wide range of pharmacological properties especially against cancer. In this context, a new series of 1,4-dihydropyridines were meticulously designed employing scaffold hybridization technique targeting the EGFR/HER2 ...
A.S.V.L. Sruthi   +8 more
doaj   +1 more source

Preparation of indole alkaloids via 1,4-dihydropyridine stage or cyano-masked iminium intermediates [PDF]

open access: yes, 2004
Methods to synthesise substituted pyridine derivatives utilising 1,4-dihydropyridines were studied. Addition of nucleophiles to N-alkyl pyridinium salts and application of the products to alkaloid synthesis were investigated.
Putkonen, Tiina
core  

A Streamline Strategy for Indication and Length of Telemetry Monitoring After TAVR

open access: yesCatheterization and Cardiovascular Interventions, Volume 107, Issue 1, Page 142-152, January 1, 2026.
ABSTRACT Background Both indication and length of ECG telemetry monitoring (TM) after transcatheter aortic valve replacement (TAVR) are not well defined. Aims We hypothesize that a targeted strategy for monitoring conductive disorders (CD) post‐TAVR can reduce the need and duration of in‐hospital TM without compromising safety. Methods We prospectively
Antonin Fournier   +13 more
wiley   +1 more source

Results of a meta-analysis comparing the tolerability of lercanidipine and other dihydropyridine calcium channel blockers

open access: yesКардиоваскулярная терапия и профилактика, 2010
Background. Results from clinical studies suggest that the dihydropyridine calcium channel blocker (d-CCB) lercanidipine may be associated with a lower incidence of peripheral edema than are older d-CCBs. Aim. To conduct a meta-analysis of published data
K. Makarounas-Kirchmann   +2 more
doaj  

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