2, 5‐Diketopiperazine Derivatives From Coculture of Escherichia coli and Mogroside V
Journal of Chemistry, Volume 2026, Issue 1, 2026.Escherichia coli (E. coli), a versatile bacterium, is also recognized for its ability to produce a range of secondary metabolites with significant biological activities. Especially in so‐called biotransformation processes, E. coli is frequently utilized to catalyze the conversion of substrate molecules into diverse compounds through biosynthesis and ...
Ya-Jie Li +9 more
wiley +1 more source
Thermal characterization of new, artificially and naturally aged leather and parchment samples [PDF]
, 2014 Handwritten books, codices and letters stored or displayed in historic buildings are vulnerable to changes in the outdoor environment due to the limited climate control. Understanding the degradation mechanisms and changes in the structure of leather and
Badea, Elena +7 more
core
Aspartame Dose‐Dependently Modulates Mitochondrial Function and Redox Balance in SH‐SY5Y Cells
Journal of Toxicology, Volume 2026, Issue 1, 2026.Aspartame (AsP), one of the most widely consumed artificial sweeteners, remains under scrutiny for its potential effects on cellular health. While generally considered safe at dietary levels, growing evidence links AsP to oxidative stress and mitochondrial dysfunction, yet its mechanistic actions remain unclear.
Lubne Aljaser +9 more
wiley +1 more source
Escherichia coli GutM4 produces 2,5-diketopiperazines and inhibits human pathogens in vitro
Electronic Journal of Biotechnology, 2017 Background: It has been a very common practice to use probiotics or their metabolites as alternative antimicrobial strategies for the treatment and prevention of infections as rampant and indiscriminate use of antibiotics causes the development of ...
Xichun Zhang +4 more
doaj +1 more source
Novel Antifungal Diketopiperazine from Marine Fungus.
The Journal of Antibiotics, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Hee-Guk, Byun +6 more
openaire +3 more sources
Synthesis and analysis of stable isotope-labelled N-acyl homoserine lactones [PDF]
, 2016 Aliphatic aldehydes were deuterated at the alpha-position via a base-catalyzed exchange reaction with D2O. These deuterated building blocks were used for the synthesis of labelled analogues of quorum sensing signal molecules belonging to the three major ...
De Kimpe, Norbert +3 more
core +2 more sources
Addressing Sustainability Challenges in Peptide Synthesis with Flow Chemistry and Machine Learning
Chemistry – A European Journal, Volume 31, Issue 72, December 23, 2025.A synthetic protocol for polypeptides 6–58 residue long, using recyclable greener solvent mixture (Anisole/DMSO) was developed and compared to traditional SPPS methods and to state‐of‐the‐art synthesizers. Abstract The high cost and the large amount of toxic waste generated during peptide production overshadow the current technology, requiring the ...
Kristóf Ferentzi +2 more
wiley +1 more source
Diverse Secondary Metabolites from the Marine-Derived Fungus Dichotomomyces cejpii F31-1
Marine Drugs, 2017 By adding l-tryptophan and l-phenylalanine to GPY medium, twenty-eight compounds, including amides, polyketides, a sesquiterpenoid, a diterpenoid, a meroterpenoid, diketopiperazines, β-carbolines, fumiquinazolines, and indole alkaloids, were discovered ...
Yan-Xiu Chen +8 more
doaj +1 more source
Microbial diversity of saline environments: searching for cytotoxic activities
AMB Express, 2017 In order to select halophilic microorganisms as a source of compounds with cytotoxic activities, a total of 135 bacterial strains were isolated from water and sediment samples collected from the Zipaquirá salt mine in the Colombian Andes.
Carolina Díaz-Cárdenas +8 more
doaj +1 more source
Synthesis of oxetane- and azetidine-containing spirocycles related to the 2,5-diketopiperazine framework [PDF]
, 2015 A simple two-step sequence is used to efficiently make novel spirocyclic analogues of the diketopiperazine nucleus. Conjugate addition of chiral α-amino esters to nitroalkenes, generated from oxetan-3-one or N-Boc-azetidin-3-one, followed by nitro group ...
Beadle, Jonathan D. +4 more
core +1 more source