Results 1 to 10 of about 6,693 (273)

Antiviral potential of diosmin against influenza A virus [PDF]

Scientific Reports
Influenza poses a global health threat. With drug-resistant strains emerging, there is an urgent need for effective antiviral drugs. This study explores antiviral potential of flavonoids against influenza A virus (IAV) and their mechanism of action.
Umarqayum AbuBakar, Zhao Xuan Low, Muhammad Zhafran Mohd Aris, Rafidah Lani, Syafiq Asnawi Zainal Abidin, Muhammad-Redha Abdullah-Zawawi, Pouya Hassandarvish, Saiful Anuar Karsani, Jasmine Elanie Khairat   +8 more
doaj   +7 more sources

The neuroprotective effects of hesperidin and diosmin in neurological disorders via targeting various signaling pathways [PDF]

Iranian Journal of Basic Medical Sciences
Diosmin and hesperidin, two flavonoid glycosides derived from citrus plants, offer numerous health benefits, whether used alone or in combination. They can mitigate neurodegenerative symptoms and reduce vascular and microbial inflammations, improving ...
Nikoo Abharian, Noushin Nikray, Afsoon Feizi, Marjan Talebi, Hamed Shafaroodi, Mehrdad Faizi   +5 more
doaj   +5 more sources

Diosmin Administration Slightly Counteracted the Changes in Bone Mechanical Properties Induced by Experimental Type 1 Diabetes in Rats [PDF]

Pharmaceuticals
Background: There is interest in substances of plant origin that may have health-promoting effects regarding diabetes and its complications, including increased risk of fractures.
Kacper Grzywnowicz, Piotr Londzin, Sylwia Klasik-Ciszewska, Weronika Borymska, Maria Zych, Ilona Kaczmarczyk-Żebrowska, Joanna Folwarczna   +6 more
doaj   +3 more sources

Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous-capillary permeability pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal, 2014
Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +6 more sources

Diosmin induces caspase-dependent apoptosis in human glioblastoma cells [PDF]

Anais da Academia Brasileira de Ciências, 2019
: Diosmin is a flavone glycoside clinically used as the main component of Daflon for the treatment of venous diseases. Several studies demonstrated that this natural compound can induce apoptosis in different tumors.
JULIANA M. SOARES, BRUNA M. DE FARIA, LUCAS M. ASCARI, SONIZA V. ALVES-LEON, JORGE M. DE SOUZA, ANTONIO G. SOARES, YRAIMA CORDEIRO, LUCIANA F. ROMÃO   +7 more
doaj   +7 more sources

Comparative study between calcium gluconate with diosmin, cabergoline, and cabergoline with diosmin in prevention of ovarian hyperstimulation syndrome in high-risk women undergoing intracytoplasmic sperm injection (ICSI) procedures [PDF]

Frontiers in Pharmacology
BackgroundOvarian Hyper-stimulation Syndrome (OHSS) is the main iatrogenic problem linked to ovarian stimulation with reproductive medications. Increased vascular permeability is considered the cause of OHSS.
Aya M. Abdallah, Amal K. Hussien, Sumaiah J. Alarfaj, Thanaa A. Elmasry, Thanaa A. Elmasry, Marwa Kamal, Hatem Sarhan, Mohammed H. Mosbeh, Eman Mohamed Sadek   +8 more
doaj   +3 more sources

Plant metabolite diosmin as the therapeutic agent in human diseases

Current Research in Pharmacology and Drug Discovery, 2022
Plant-derived flavonoids have been the focus of research for many years mainly in the last decade owing to their therapeutic properties. So far, about 4000 flavonoids have been identified from plants and diosmin (a flavone glycoside) is one of them ...
Saad Mustafa, Mahmood Akbar, Mohammad Aasif Khan, Kumari Sunita, Shabana Parveen, Jogendra Singh Pawar, Sheersh Massey, Nupur Rani Agarwal, Syed Akhtar Husain   +8 more
doaj   +2 more sources

Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation

BMC Complementary Medicine and Therapies
Background Renal fibrosis is considered an irreversible pathological process and the ultimate common pathway for the development of all types of chronic kidney diseases and renal failure.
Wen-Man Zhao, Xun-Liang Li, Yuyu Zhu, Rui Shi, Zhi-Juan Wang, Jian-Ping Xiao, De-Guang Wang   +6 more
doaj   +2 more sources

Diosmin mitigates high glucose-induced endoplasmic reticulum stress through PI3K/AKT pathway in HK-2 cells [PDF]

BMC Complementary Medicine and Therapies, 2022
Background Diosmin has been reported to treat diabetes, but its role in diabetic nephropathy (DN) remains unclear. This research investigated the mechanism by which diosmin alleviated high glucose (HG)-induced HK-2 cell injury. Methods First, we used CCK-
Jiuhong Deng, Chao Zheng, Zhou Hua, Haideng Ci, Guiying Wang, Lijing Chen   +5 more
doaj   +2 more sources

Zein-sodium caseinate-diosmin nanoparticles as a promising anti-cancer agent with targeted efficacy against A2780 cell line. [PDF]

Sci Rep
This research investigated the potential of zein–sodium caseinate–diosmin nanoparticles (ZCD-NPs) as an anti-cancer agent against the A2780 cell line. Dynamic light scattering (DLS) analysis showed that ZCD-NPs have an average size of 265.30 nm with a ...
Faezi M, Motavalizadehkakhky A, Homayouni Tabrizi M, Dolatabadi S, Es-Haghi A.   +4 more
europepmc   +2 more sources