Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous-capillary permeability pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]
EFSA Journal, 2014 Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
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Diosmin Administration Slightly Counteracted the Changes in Bone Mechanical Properties Induced by Experimental Type 1 Diabetes in Rats [PDF]
PharmaceuticalsBackground: There is interest in substances of plant origin that may have health-promoting effects regarding diabetes and its complications, including increased risk of fractures.
Kacper Grzywnowicz +6 more
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Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous tone pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]
EFSA Journal, 2014 Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj +4 more sources
Comparative study between calcium gluconate with diosmin, cabergoline, and cabergoline with diosmin in prevention of ovarian hyperstimulation syndrome in high-risk women undergoing intracytoplasmic sperm injection (ICSI) procedures [PDF]
Frontiers in PharmacologyBackgroundOvarian Hyper-stimulation Syndrome (OHSS) is the main iatrogenic problem linked to ovarian stimulation with reproductive medications. Increased vascular permeability is considered the cause of OHSS.
Aya M. Abdallah +8 more
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Antiviral potential of diosmin against influenza A virus [PDF]
Scientific ReportsInfluenza poses a global health threat. With drug-resistant strains emerging, there is an urgent need for effective antiviral drugs. This study explores antiviral potential of flavonoids against influenza A virus (IAV) and their mechanism of action.
Umarqayum AbuBakar +8 more
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Tailored biosynthesis of diosmin through reconstitution of the flavonoid pathway in Nicotiana benthamiana [PDF]
Frontiers in Plant ScienceThe flavonoid diosmin (diosmetin 7-O-rutinoside) is used as a therapeutic agent for disorders of the blood vessels such as hemorrhoids and varicose veins. Diosmin is commercially produced using semi-synthetic methods involving the oxidation of hesperidin,
Hyo Lee +5 more
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Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway [PDF]
MedicinaBackground and Objectives: This study aimed to investigate the protective effect of diosmin and hesperidin in diabetic neuropathy using a rat model, focusing on their impact on nerve regeneration through the fibroblast growth factor 21 (FGF21) and ...
Birzat Emre Gölboyu +4 more
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The neuroprotective effects of hesperidin and diosmin in neurological disorders via targeting various signaling pathways [PDF]
Iranian Journal of Basic Medical SciencesDiosmin and hesperidin, two flavonoid glycosides derived from citrus plants, offer numerous health benefits, whether used alone or in combination. They can mitigate neurodegenerative symptoms and reduce vascular and microbial inflammations, improving ...
Nikoo Abharian +5 more
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Heliyon, 2021 Hyssop (Hyssopus officinalis L.) is a perennial subshrub, which is distributed across the eastern Mediterranean region to central Asia. One of the most important bioactive compounds of hyssop is diosmin, a flavone glycoside of diosmetin, with application
Zhaleh Soheilikhah +3 more
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Plant metabolite diosmin as the therapeutic agent in human diseases
Current Research in Pharmacology and Drug Discovery, 2022 Plant-derived flavonoids have been the focus of research for many years mainly in the last decade owing to their therapeutic properties. So far, about 4000 flavonoids have been identified from plants and diosmin (a flavone glycoside) is one of them ...
Saad Mustafa +8 more
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