Diosmin Potentiates the Antidiabetic Effects of Linagliptin in Nicotinamide/Streptozotocin-Induced Diabetic Wistar Rats. [PDF]
Pharmaceuticals (Basel)Background/Objectives: Natural therapeutics for the treatment of diabetes mellitus represent a common challenge for many researchers. Thus, the aim of this study was to evaluate the antihyperglycemic and anti-inflammatory effects and the hepatic ...
Abbas EB +5 more
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Impact of nafcillin and diosmin on the attachment, invasion, and stress survival of Salmonella Typhimurium. [PDF]
Sci RepSalmonella Typhimurium is an invasive intracellular pathogen that employs various factors for its survival within host cells. To mitigate S. Typhimurium survival, it is crucial to identify factors that influence bacterial survival and to develop drugs ...
Narimisa N +5 more
europepmc +2 more sources
Diosmin or Hesperidin? Comparison of Antioxidative Action of Two Venoactive Flavonoids in Type 1 Diabetic Rats. [PDF]
Int J Mol SciDiabetes mellitus and chronic venous disease (CVD) are multifactorial, long-lasting diseases. Although usually considered separately, they often coexist, and individuals with diabetes are more prone to CVD development. Despite different etiology, CVD and
Borymska W +4 more
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Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis [PDF]
Micromachines, 2021 Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification.
Iulia Gabriela David +5 more
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Scientific Opinion on the substantiation of a health claim related to a combination of diosmin, troxerutin and hesperidin and maintenance of normal venous tone pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]
EFSA Journal, 2014 Following an application from Omikron Italia S.r.l., submitted pursuant to Article 13.5 of Regulation (EC) No 1924/2006 via the Competent Authority of Italy, the Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
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Tailored biosynthesis of diosmin through reconstitution of the flavonoid pathway in Nicotiana benthamiana [PDF]
Frontiers in Plant ScienceThe flavonoid diosmin (diosmetin 7-O-rutinoside) is used as a therapeutic agent for disorders of the blood vessels such as hemorrhoids and varicose veins. Diosmin is commercially produced using semi-synthetic methods involving the oxidation of hesperidin,
Hyo Lee +5 more
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Potential and Therapeutic Roles of Diosmin in Human Diseases
Biomedicines, 2022 Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade.
Etimad Huwait, Mohammad Mobashir
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Polymer carrier selection for creation of diosmin solid dispersion system by hot melt extrusion
Разработка и регистрация лекарственных средств, 2023 Introduction. The extremely unfavorable physical, chemical and functional properties of diosmin, a component of a number of popular phleboprotective drugs, cause an increased therapeutic dosage of the active pharmaceutical ingredient (API) in the dosage ...
A. A. Danilova +5 more
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Brain DisordersSchizophrenia is a major neuropsychiatric disorder associated with neurochemical perturbations characterized by behavioral abnormalities, for which effective treatment remains elusive. The current study investigated the neurotransmitter modulatory effect
Aya-Ebi Okubo Eneni +3 more
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Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway [PDF]
MedicinaBackground and Objectives: This study aimed to investigate the protective effect of diosmin and hesperidin in diabetic neuropathy using a rat model, focusing on their impact on nerve regeneration through the fibroblast growth factor 21 (FGF21) and ...
Birzat Emre Gölboyu +4 more
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