Potential and Therapeutic Roles of Diosmin in Human Diseases
Biomedicines, 2022 Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade.
Etimad Huwait, Mohammad Mobashir
doaj +3 more sources
Diosmin and Hesperidin Have a Protective Effect in Diabetic Neuropathy via the FGF21 and Galectin-3 Pathway. [PDF]
Medicina (Kaunas)Background and Objectives: This study aimed to investigate the protective effect of diosmin and hesperidin in diabetic neuropathy using a rat model, focusing on their impact on nerve regeneration through the fibroblast growth factor 21 (FGF21) and ...
Gölboyu BE +4 more
europepmc +2 more sources
Diosmin/hesperidin: a cooperating tandem, or is diosmin crucial and hesperidin an inactive ingredient only? [PDF]
Vnitřní lékařství, 2020 With the advent of novel monocomponent venoactive drugs containing the flavonoid diosmin, the need has arisen to answer the question of therapeutic equivalence of the widely used micronized purified flavonoid fraction (MPFF) contained in Detralex and of the currently introduced monocomponent venoactive drugs.
Debora Karetová +2 more
openalex +3 more sources
Evaluation of the Effect of Loratadine versus Diosmin/Hesperidin Combination on Vinca Alkaloids-Induced Neuropathy: A Randomized Controlled Clinical Trial [PDF]
PharmaceuticalsNeurological injury is a crucial problem that interferes with the therapeutic use of vinca alkaloids as well as the quality of patient life. This study was conducted to assess the impact of using loratadine or diosmin/hesperidin on neuropathy induced by ...
Noha Kamal +4 more
doaj +2 more sources
Synergistic therapeutic approach for hemorrhoids: integrating mesenchymal stem cells with diosmin-hesperidin to target tissue edema and inflammation. [PDF]
Arch Med SciKusumo MHB +3 more
europepmc +2 more sources
Heliyon, 2021 Hyssop (Hyssopus officinalis L.) is a perennial subshrub, which is distributed across the eastern Mediterranean region to central Asia. One of the most important bioactive compounds of hyssop is diosmin, a flavone glycoside of diosmetin, with application
Zhaleh Soheilikhah +3 more
doaj +1 more source
Exploring absorption indices for a variety of polyphenols through Caco-2 cell model: insights from permeability studies and principal component analysis. [PDF]
J Sci Food AgricAbstract BACKGROUND Phytochemicals have long been utilized as active ingredients in the developing of novel functional foods or drugs due to their diverse biological and pharmacological effects. Many studies have demonstrated that polyphenols exhibit low absorption rates and are extensively metabolized into various metabolites, resulting in ...
Lee DH +7 more
europepmc +2 more sources
BMC Complementary Medicine and Therapies, 2023 Background Interstitial fibrosis is involved in the progression of various chronic kidney diseases and renal failure. Diosmin is a naturally occurring flavonoid glycoside that has antioxidant, anti-inflammatory, and antifibrotic activities.
Wen-Man Zhao +5 more
doaj +1 more source
Diosmin Alleviates Venous Injury and Muscle Damage in a Mouse Model of Iliac Vein Stenosis
Frontiers in Cardiovascular Medicine, 2022 Chronic venous disease (CVD) is a progressive inflammatory disease that increases in prevalence with age. Elucidating the underlying molecular mechanism of CVD development is essential for disease prevention and treatment.
Zhiye Guo +5 more
doaj +1 more source
Disposable Pencil Graphite Electrode for Diosmin Voltammetric Analysis
Micromachines, 2021 Diosmin (DIO) is a naturally occurring flavonoid with multiple beneficial effects on human health. The presence of different hydroxyl groups in diosmin structure enables its electrochemical investigation and quantification.
Iulia Gabriela David +5 more
doaj +1 more source