Evaluation of the Effect of Loratadine versus Diosmin/Hesperidin Combination on Vinca Alkaloids-Induced Neuropathy: A Randomized Controlled Clinical Trial [PDF]
PharmaceuticalsNeurological injury is a crucial problem that interferes with the therapeutic use of vinca alkaloids as well as the quality of patient life. This study was conducted to assess the impact of using loratadine or diosmin/hesperidin on neuropathy induced by ...
Noha Kamal +4 more
doaj +2 more sources
Diosmin/hesperidin: a cooperating tandem, or is diosmin crucial and hesperidin an inactive ingredient only? [PDF]
Vnitřní lékařství, 2020 With the advent of novel monocomponent venoactive drugs containing the flavonoid diosmin, the need has arisen to answer the question of therapeutic equivalence of the widely used micronized purified flavonoid fraction (MPFF) contained in Detralex and of the currently introduced monocomponent venoactive drugs.
Debora Karetová +2 more
openalex +3 more sources
[Diosmin-hesperidin-induced DRESS syndrome: immune reactivation by herpesvirus].
Revista Alergia MéxicoBACKGROUND Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe cutaneous adverse reaction. The incidence is 1-1,000,000 with a mortality rate of 3.8-10%, and it is a disease associated with reactivation of the herpes simplex virus.
Nataly Flores-García +4 more
semanticscholar +3 more sources
Hepatoprotective effects of diosmin: a narrative review
Naunyn-Schmiedeberg's Archives of PharmacologyLiver diseases represent a formidable global health threat. Hesperidin, a flavonoid found in citrus fruits, is the source of diosmin (DS). The in vivo and in vitro investigations of the pharmacological effects of DS reveal that it exhibits tremendous ...
Emad H. M. Hassanein +3 more
semanticscholar +3 more sources
Synergistic therapeutic approach for hemorrhoids: integrating mesenchymal stem cells with diosmin-hesperidin to target tissue edema and inflammation. [PDF]
Arch Med SciKusumo MHB +3 more
europepmc +3 more sources
Heliyon, 2021 Hyssop (Hyssopus officinalis L.) is a perennial subshrub, which is distributed across the eastern Mediterranean region to central Asia. One of the most important bioactive compounds of hyssop is diosmin, a flavone glycoside of diosmetin, with application
Zhaleh Soheilikhah +3 more
doaj +1 more source
BMC Complementary Medicine and Therapies, 2023 Background Interstitial fibrosis is involved in the progression of various chronic kidney diseases and renal failure. Diosmin is a naturally occurring flavonoid glycoside that has antioxidant, anti-inflammatory, and antifibrotic activities.
Wen-Man Zhao +5 more
doaj +1 more source
Diosmin Alleviates Venous Injury and Muscle Damage in a Mouse Model of Iliac Vein Stenosis
Frontiers in Cardiovascular Medicine, 2022 Chronic venous disease (CVD) is a progressive inflammatory disease that increases in prevalence with age. Elucidating the underlying molecular mechanism of CVD development is essential for disease prevention and treatment.
Zhiye Guo +5 more
doaj +1 more source
Antioxidants, 2021 Hepatotoxicity caused by chemotherapeutic drugs (e.g., doxorubicin) is of critical concern in cancer therapy. This study focused on investigating the modulatory effects of diosmin against doxorubicin-induced hepatotoxicity in Male Wistar rats.
Abdullah F. AlAsmari +11 more
doaj +1 more source
Study of C- and O-glycosylflavones in sugarcane extracts using liquid chromatography: exact mass measurement mass spectrometry [PDF]
, 2008 The flavonoids present in sugarcane (Saccharum officinarum) extracts were analyzed by liquid chromatography - mass spectrometry (LC-MS), and a study of the fragmentation patterns of selected flavonoids was conducted using orthogonal acceleration time-of ...
COLOMBO, Renata +2 more
core +1 more source