Results 91 to 100 of about 6,648 (299)

Optical detection of di- and triphosphate anions with mixed monolayer-protected gold nanoparticles containing zinc(II)–dipicolylamine complexes

Beilstein Journal of Organic Chemistry, 2020
Gold nanoparticles covered with a mixture of ligands of which one type contains solubilizing triethylene glycol residues and the other peripheral zinc(II)–dipicolylamine (DPA) complexes allowed the optical detection of hydrogenphosphate, diphosphate, and
Lena Reinke, Julia Bartl, Marcus Koch, Stefan Kubik   +3 more
doaj   +1 more source

5'-Phosphoramidates and 5'-diphosphates of 2'-O-allyl-β-D- arabinofuranosyl-uracil, -cytosine, and -adenine: Inhibition of ribonucleotide reductase

, 1999
Continuing our studies on ribonucleotide reductase (RNR) mechanism-based inhibitors, we have now prepd. the diphosphates (DP) of 2'-O-allyl-1-β-D-arabinofuranosyl-uracil and -cytosine and 2'-O-allyl-9-β-D-arabinofuranosyl-adenine and evaluated their ...
DURINI, Elisa, VERTUANI, Silvia, BALZARINI JAN, BARALDI, Pier Giovanni, KARLSSON ANNA, BUZZONI VALENTINA, THELANDER LARS, DE CLERCQ ERIK, MANFREDINI, Stefano   +8 more
core   +1 more source

Synthesis, crystal structures, substitutional and comparative structural analysis of copper diphosphates LiNaCuP2O7, LiKCuP2O7 and Rb0.5Na1.5CuP2O7 [PDF]

, 2018
The title compounds are members of the M2O-CuO-P2O5 system (M = Li, Na, K and Rb), where the lithium, sodium, potassium, rubidium and cesium phases have already been structurally characterized.
Boughzala, Habib, Fitouri, Ines
core   +1 more source

Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood

Advanced NanoBiomed Research, EarlyView.
Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus, Broder Poschkamp, Lea Miebach, Anke Schmidt, Linus Hübner, Julia van der Linde   +5 more
wiley   +1 more source

Spectroscopic and theoretical approaches for studying radical reactions in class I ribonucleotide reductase [PDF]

, 2005
Ribonucleotide reductases (RNRs) catalyze the production of deoxyribonucleotides, which are essential for DNA synthesis and repair in all organisms.
Lendzian, F., Bennati, Marina, Schmittle, M., Schmittel, Michael, Zipse, H., Lendzian, Friedhelm, Bennati, M., Zipse, Hendrik   +7 more
core   +1 more source

Variant Bacterial Riboswitches Associated with Nucleotide Hydrolase Genes Sense Nucleoside Diphosphates

, 2018
The ykkC RNA motif was a long-standing orphan riboswitch candidate that has recently been proposed to encompass at least five distinct bacterial riboswitch classes.
Madeline E. Sherlock (2818915), Ronald R. Breaker, Madeline E. Sherlock, Ronald R. Breaker (6909), Harini Sadeeshkumar (5684132), Harini Sadeeshkumar   +5 more
core   +2 more sources

Farnesyl Diphosphate Synthase Assay

, 2014
Farnesyl diphosphate synthase (FPS) catalyzes the sequential head-to-tail condensation of isopentenyl diphosphate (IPP, C5) with dimethylallyl diphosphate (DMAPP, C5) and geranyl diphosphate (GPP, C10) to produce farnesyl diphosphate (FPP, C15). This short-chain prenyl diphosphate constitutes a key branch-point of the isoprenoid biosynthetic pathway ...
Arró, Montserrat, Manzano, David, Ferrer, Albert   +2 more
openaire   +3 more sources

Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates and Diphosphates:  A Potential Route to New Bone Antiresorption and Antiparasitic Agents

, 2016
We report the inhibition of a human recombinant geranylgeranyl diphosphate synthase (GGPPSase) by 23 bisphosphonates and six azaprenyl diphosphates. The IC50 values range from 140 nM to 690 μM. None of the nitrogen-containing bisphosphonates that inhibit
John A. Cieslak (2316979), Hiroshi Sagami (3013197), Timothy C. Loftus (2727778), Robert M. Coates (1270191), Michael B. Martin (3010833), Christina M. Szabo (1820266), Christopher R. Lea (2727772), Eric Oldfield (558367), Sayaka Fukura (3013203), Yoshihiro Matsumura (2411107), John M. Sanders (1503199), Suraj Sengupta (3013194), Hyung-Jae Lee (3013200), Ali Koohang (2284417)   +13 more
core   +1 more source

Spectroscopic characterization of mixed cation diphosphates of the type MI FeIIIP2O7 (with MI¼Li, Na, K, Rb, Cs, Ag) [PDF]

, 2013
The mixed cation diphosphates of composition MI FeIIIP2O7 have been prepared using the so called co-precipitation method starting with Fe(III) and M(I) nitrate solutions and solid (NH4)H2PO4, and characterized by X-ray powder diffractometry. The infrared
Baran, Enrique José, Mercader, Roberto Carlos, Parajón Costa, Beatriz Susana   +2 more
core   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura B. Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore   +19 more
wiley   +1 more source