Results 71 to 80 of about 25,921 (206)
Cyclooctyne and cycloocten-5-yne undergo, at room temperature, a 1,3-dipolar cycloaddition with dialkyl acetylenedicarboxylates 1a,b to generate furan-derived short-lived intermediates 2, which can be trapped by two additional equivalents of 1a,b or ...
Klaus Banert +8 more
doaj +1 more source
A solvent‐free, two‐step chemical vapor polymerization enables efficient, substrate‐independent synthesis of surface‐attached polypeptide films. Initiator deposition via CVD is followed by NCA ring‐opening polymerization. Characterization confirms film formation and functionalization, allowing precise micropatterning and bioactive surface design for ...
Domenic Kratzer +4 more
wiley +1 more source
5-Benzoyl-N,4-diphenyl-4,5-dihydro-1H-pyrazole-3-carboxamide
The title compound, C23H19N3O2, was synthesized by the 1,3-dipolar cycloaddition reaction of N-phenyl-α-diazoacetamide and chalcone. In the molecule, the pyrazoline ring assumes an envelope conformation.
Long He
doaj +1 more source
An update on the synthesis and reactivity of spiro-fused β-lactams [PDF]
Beta-Lactam ring-containing compounds play a pivotal role in drug design and synthetic chemistry. Spirocyclic beta-lactams, representing an important beta-lactam subclass, have recently attracted considerable interest with respect to new synthetic ...
D'hooghe, Matthias, Dao Thi, Hang
core +1 more source
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley +1 more source
Ultrasound-promoted synthesis of novel fused heterocycles by criss-cross cycloaddition
This work reports a novel and highly efficient methodology for the synthesis of perhydrotriazolotriazoledithions from two successive 1,3-dipolar cycloaddition under ultrasound irradiation.
Javad Safari +2 more
doaj +1 more source
Catalytic Asymmetric Synthesis of Bicycloprolines by a 1,3-Dipolar Cycloaddition/Intramolecular Alkylation Strategy [PDF]
This document is the Accepted Manuscript version of a Published Work that appeared in final form inJournal of Organic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher.
Adrio, Javier +4 more
core +3 more sources
Structure and Mechanism of PhdC, a Prenylated‐Flavin Maturase
ABSTRACT Prenylated flavin mononucleotide (prFMN) is a modified flavin cofactor required by the UbiD family of (de)carboxylase enzymes. While the reduced prFMNH2 form is produced by the flavin prenyltransferase UbiX, the corresponding two‐electron oxidized prFMNiminium form is required to support UbiD catalysis. Thus, oxidative maturation of prFMNH2 is
Dominic R. Whittall +4 more
wiley +1 more source
Background: This research centers on the development and spectroscopic characterization of new quinazolin-4(3H)-one-isoxazole derivatives (5a–e). The aim was to investigate the regioselectivity of the 1,3-dipolar cycloaddition involving arylnitriloxides ...
Yassine Rhazi +13 more
doaj +1 more source
An overview of the cycloaddition chemistry of fulvenes and emerging applications
The unusual electronic properties and unique reactivity of fulvenes have interested researchers for over a century. The propensity to form dipolar structures at relatively low temperatures and to participate as various components in cycloaddition ...
Ellen Swan +2 more
doaj +1 more source

