Results 11 to 20 of about 966,959 (266)
Biomarkers in Alzheimer’s Disease [PDF]
Frontiers in Neurology, 2011 Alzheimer's disease (AD) is the most common form of dementia in the elderly, and it is characterized by progressive impairment in multiple cognitive domains of sufficient severity to interfere with individuals' daily living activities. Historically, the diagnosis of AD has been based on the identification of a clinical syndrome, and accuracy studies of
Mario eRiverol +2 more
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Biomarkers in Alzheimer’s disease
Advances in Laboratory Medicine / Avances en Medicina de Laboratorio, 2020 Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disease. AD is the main cause of dementia worldwide and aging is the main risk factor for developing the illness. AD classical diagnostic criteria rely on clinical data.
Janeiro Manuel H. +7 more
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Clinical characteristics of children infected with SARS-CoV-2 in Italy
Italian Journal of Pediatrics, 2021 Background Since December 2019 coronavirus disease (COVID-19) emerged in Wuhan and spread rapidly worldwide. Despite the high number of people affected, data on clinical features and prognostic factors in children and adolescents are limited.
Isabella Tarissi De Jacobis +7 more
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Biomarkers of Alzheimer Disease [PDF]
The Journal of Applied Laboratory Medicine, 2019 AbstractBackgroundAlzheimer disease (AD) was once a clinical diagnosis confirmed by postmortem autopsy. Today, with the development of AD biomarkers, laboratory assays to detect AD pathology are able to complement clinical diagnosis in symptomatic individuals with uncertain diagnosis.
Melissa M, Budelier, Randall J, Bateman
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Biomarkers in Rare Diseases [PDF]
International Journal of Molecular Sciences, 2021 There is no single global definition of a rare disease, and for different geographical areas the definition is based on the disease occurrence in that population [...]
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Public Health Genomics, 2013 <b><i>Background:</i></b> Nowadays 7,000 rare diseases (RDs) have been identified with a prevalence less than 5/10,000. Despite of the enormous effort the European Union (EU) has already invested in this field, still 4,000 RDs remain orphan of genetic diagnosis and causative gene identification.
FERLINI, Alessandra +2 more
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Biomarkers for Osteoarthritis Diseases
Life, 2022 Growing evidence has revealed the pivotal role of inflammatory biomarkers in the pathogenesis of osteoarthritis. There is significant interest in the prognostic value of select biomarkers, given the potential for early identification and treatment of patients at risk of osteoarthritis prior to the development of irreversible clinical disease.
Jacob A. Braaten +6 more
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Altered metabolic pathways in classic and hypervirulent Klebsiella pneumoniae isolates revealed by proteomics analysis [PDF]
Archives of Biological Sciences, 2022 Klebsiella pneumoniae is an opportunistic pathogen that causes a wide range of infections. The emergence and spread of hypervirulent K. pneumoniae (hvKp), which appears to be different from the classical K.
Yu Hui +4 more
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Biomarkers and Heart Disease [PDF]
Journal of Clinical Sleep Medicine, 2011 This review will focus on the evaluation of biomarkers and surrogate endpoints in chronic disease risk with a focus on cardiovascular disease. It provides an example of how identification of relevant biomarkers might be useful in sleep research and clinical care.
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Italian Journal of Pediatrics, 2020 Background Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in the pediatric population worldwide and an important cause of death in developing countries.
Isabella Tarissi De Jacobis +11 more
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