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Animal Models of Diseases [PDF]

Proceedings of the 2nd International University of Malaya Research Imaging Symposium (UMRIS) 2005: Fundamentals of Molecular Imaging, 2005
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Animal models of Alzheimer’s disease

Folia Pharmacologica Japonica, 2014
Takaomi C. Saido, akashi Saito
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Gemin6 promotes c‐Myc stabilisation and non‐small cell lung cancer progression via accelerating AURKB mRNA maturation

Clinical and Translational Medicine, 2022
Jie Lin, Baiyang Liu, Yong Zhang, Li Lv, Dating Cheng, Wenhui Zhang, Yulin Shi, Xiulin Jiang, Lin Tang, Yixiao Yuan, Haoqing Zhai, Qiushuo Shen, Qiuxia Xiong, Zhixian Jin, Yongbin Chen, Cuiping Yang   +15 more
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Animal models of Cushing's disease

Trends in Endocrinology & Metabolism, 1994
Cushing's disease, defined as hyperadrenocorticism resulting from excessive secretion of pituitary ACTH, occurs spontaneously and quite commonly in dogs and horses. In dogs, as in humans, the disease is usually associated with a small tumor of the pituitary pars distalis.
Mark E. Peterson, Robert J. Kemppainen
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Animal Models for Human Diseases [PDF]

Perspectives in Biology and Medicine, 1982
The use of animal models for the study of human disease is for the most part a recent development. This discussion of the use of animal models for human diseases directs attention to the sterile period early advances some personal experiences the human as the model biological oddities among common laboratory animals malignancies in laboratory animals ...
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Animal models of Parkinson's disease

BioEssays, 2002
AbstractAnimal models are important tools in experimental medical science to better understand pathogenesis of human diseases. Once developed, these models can be exploited to test therapeutic approaches for treating functional disturbances observed in the disease of interest. On the basis of experimental and clinical findings, Parkinson's disease (PD)
Ranjita Betarbet, Todd B. Sherer, J. Timothy Greenamyre   +2 more
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Animal Models of Nonthyroidal Disease*

Endocrine Reviews, 1985
Rats bearing transplantable Walker 256 carcinoma provide an opportunity to assess thyroid function and activity during an interval of time when the tumor has not affected growth rate. Rats with tumor have decreased serum T4 and T3 concentration and decreased serum FT4 and FT3 as well.
Martin I. Surks, Joseph M. Tibaldi
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Animal Models of Neurological Disease

2010
The use of animal models to study human pathology has proved valuable in a number of fields. Animal models of neurological disease have successfully and accurately recreated many aspects of human illness allowing for in-depth study ofneuropathophysiology.
Tomas Garzon-Muvdi, Alfredo Quinones-Hinojosa, Rohit Mahajan, Amol Shah, Vincent J. Duenas   +4 more
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Animal models of Wilson disease

2017
Wilson disease (WD) is caused by ATPase copper-transporting beta (ATP7B) mutations and results in copper toxicity in liver and brain. Although the defective gene was identified in 1993, the specific mechanisms underlying copper toxicity and the remarkable phenotypic diversity of the disease are still poorly understood.
D. Huster, Valentina Medici
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Animal Models of Neurodegenerative Diseases

2009
Animal models of neurodegenerative disease are excellent tools for studying pathogenesis and therapies including cellular transplantation. In this chapter, we describe different models of Huntington's disease and Parkinson's disease, stereotactic surgery (used in creation of lesion models and transplantation) and finally transplantation studies in ...
Harald Pruess, Roger A. Barker, Andrew W. Michell, Wendy Phillips   +3 more
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