Results 31 to 40 of about 125,308 (293)

Controlled arterial hypertension and adverse event free survival rate in heart recipients

open access: yesКардиоваскулярная терапия и профилактика, 2018
Aim. To evaluate the prevalence of arterial hypertension (AH) in heart transplant recipients, and its influence on the risk of adverse events, as the efficacy and safety of antihypertension medications (AHM).Material and methods.
A. О. Shevchenko   +4 more
doaj   +1 more source

Pharmacotherapy for Essential Hypertension: A Brief Review

open access: yesMethodist DeBakey Cardiovascular Journal, 2022
Hypertension is one of the leading causes of disability-adjusted life years and mortality, with approximately 15% prevalence worldwide. Most patients with hypertension from low- to high-income countries do not receive treatment.
Behnam Heidari   +2 more
doaj   +1 more source

Cardiovascular and Renal Outcomes with Ertugliflozin by Baseline Use of Renin-Angiotensin-Aldosterone System Inhibitors or Diuretics, Including Mineralocorticoid Receptor Antagonist: Analyses from the VERTIS CV Trial

open access: yesKidney Diseases
Introduction: VERTIS CV was a placebo-controlled cardiovascular (CV) outcome trial evaluating the sodium-glucose cotransporter 2 inhibitor ertugliflozin in patients with type 2 diabetes and established atherosclerotic CV disease.
David Z.I. Cherney   +10 more
doaj   +1 more source

Association of diuretics with falls and wrist fractures: a Mendelian randomization study

open access: yesFrontiers in Public Health
BackgroundThe association between diuretics and falls in older adult has been reported in previous studies, but discrepancy remains between the different types of diuretics.
Fei Liu   +5 more
doaj   +1 more source

Diuretics for hypertension from the perspective of novel clinical guidelines and meta-analyzes

open access: yesРоссийский кардиологический журнал, 2021
A review of the efficacy and safety of diuretics in hypertension was carried out from the standpoint of current clinical guidelines. Also, updated data from metaanalyzes of the efficacy and metabolic effects of diuretic therapy were reviewed.
S. V. Nedogoda
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Chronic Bumetanide Infusion Alters Young Neuron Morphology in the Dentate Gyrus Without Affecting Contextual Fear Memory

open access: yesFrontiers in Neuroscience, 2020
Young neurons in the adult brain are key to some types of learning and memory. They integrate in the dentate gyrus (DG) of the hippocampus contributing to such cognitive processes following timely developmental events.
Gibrán Gómez-Correa   +2 more
doaj   +1 more source

Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry   +16 more
wiley   +1 more source

A prospective study of the effect of antihypertensive medications on the sexual functions of hypertensive adult male patients

open access: yesFuture Science OA, 2020
Background: The potential for antihypertensive medications to produce deleterious adverse effects on sexual functions among hypertensive adult male patients has been widely reported, such adverse effects may limit drug adherence and compliance.
Akinwumi Akinyinka Akinyede   +5 more
doaj   +1 more source

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

open access: yesArthritis Care &Research, EarlyView.
Objective Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged ≥70 years old.
Amanda J. Rickard   +15 more
wiley   +1 more source

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