Results 61 to 70 of about 63,738 (185)
Clinical Pharmacology &Therapeutics, EarlyView.Autosomal dominant polycystic kidney disease is the most prevalent inherited kidney disease and leads to bilateral kidney enlargement and progressive loss of renal function, often over decades. Comorbidities include hypertension, flank pain, and bacterial infections. The condition often necessitates prolonged multidrug therapy.
Annika C. Tillmann +6 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +1 more source
Effects of the Dietary Supplement 5α‐Hydroxy‐Laxogenin in the Orchiectomized Rat Model
Drug Testing and Analysis, EarlyView.The dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated in the castrated male rat for potential androgenic and anabolic effects. Moreover, androgen receptor binding of 5α‐hydroxy‐laxogenin was modelled by in silico docking. While molecular modelling supports androgen receptor binding, we observed neither androgenic nor anabolic effects ...
Daniel Derwand +4 more
wiley +1 more source
The G protein-gated potassium current I(K,ACh) is constitutively active in patients with chronic atrial fibrillation [PDF]
, 2005 Background— The molecular mechanism of increased background inward rectifier current (IK1) in atrial fibrillation (AF) is not fully understood. We tested whether constitutively active acetylcholine (ACh)-activated IK,ACh contributes to enhanced basal ...
Christ, T. +7 more
core +1 more source
Ascites of patients with solid tumors shows distinct inflammatory patterns
Cancer Communications, EarlyView.
Julia M. Berger +19 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.A survey of 200 sports supplements purchased online in Australia and analysed for WADA Prohibited Substances. Athlete education regarding the use of sports supplements remains a high priority as 35% of the products contained WADA Prohibited Substances. ABSTRACT Sports supplements are used extensively by people involved in competitive sports. However, a
Louise Barker +4 more
wiley +1 more source
Sacubitril/valsartan reduces serum uric acid concentration, an independent predictor of adverse outcomes in PARADIGM-HF [PDF]
, 2017 Aims: Elevated serum uric acid concentration (SUA) has been associated with an increased risk of cardiovascular disease, but this may be due to unmeasured confounders.
Chen, Chen-Huan +16 more
core +3 more sources
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Limited research has examined the function or consequences of dietary restriction among individuals for whom it may serve differential purposes, such as those with food insecurity. Indeed, food insecurity may uniquely relate to differential functions for engaging in dietary restriction, which may relate to subsequent changes in mood;
Yvette Karvay +5 more
wiley +1 more source
Endothelial glycocalyx: Role in body fluid homeostasis and fluid management [PDF]
, 2019 Endothelial glycocalyx layer (EGL) coating the luminal surface of vascular endothelium plays an essential role in maintaining the normal fluid homeostasis of the body.
Goswami, Shreya, Kundra, Pankaj
core +2 more sources