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Methionine deficiency causes spermatogonial apoptosis via oxidative stress and DNA damage response pathway. [PDF]
Wang W, Ruan Y, Ting G.
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Histone Phosphorylation in DNA Damage Response. [PDF]
Gong P, Guo Z, Wang S, Gao S, Cao Q.
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C9orf72-related amyotrophic lateral sclerosis-frontotemporal dementia and links to the DNA damage response: a systematic review. [PDF]
Almalki S +4 more
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USP7 promotes chemotherapy resistance and DNA damage response through stabilizing and deubiquitinating KDM4A in bladder cancer. [PDF]
Yang H +14 more
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Targeting the DNA damage response prevents regrowth of colorectal peritoneal metastasis-derived organoids following treatment with mitomycin C. [PDF]
van Megesen K +6 more
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DNA Damage Response in Nucleoli
Molecular Biology, 2021Nucleoli, the largest subnuclear compartments, are formed around arrays of ribosomal gene repeats transcribed by RNA polymerase I. The primary function of nucleoli is ribosome biogenesis. Specific DNA damage response mechanisms exist to maintain the genomic stability of ribosomal repeats.
A K, Velichko, S V, Razin, O L, Kantidze
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Cellular Response to DNA Damage
Annals of the New York Academy of Sciences, 2006Abstract: Eukaryotic cells, from yeast to man, possess evolutionarily conserved mechanisms to accurately and efficiently repair the overwhelming majority of DNA damage, thereby ensuring genomic integrity. Important repair pathways include base excision repair, nucleotide excision repair, mismatch repair, non‐homologous end‐joining, and homologous ...
Johnny, Kao +4 more
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DNA damage response and transcription
DNA Repair, 2011A network of DNA damage surveillance systems is triggered by sensing of DNA lesions and the initiation of a signal transduction cascade that activates genome-protection pathways including nucleotide excision repair (NER). NER operates through coordinated assembly of repair factors into pre- and post-incision complexes.
Lagerwerf, S. +4 more
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