Results 191 to 200 of about 70,351 (245)

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Replication fork stalling in late S-phase elicits nascent strand degradation by DNA mismatch repair. [PDF]

Nucleic Acids Res
Colicino-Murbach E, Hathaway C, Dungrawala H.   +2 more
europepmc   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Dissecting DNA-mismatch-repair-driven mutational processes in human cells

Owusu M, Menche J, Loizou J, Weghorn D, Weghorn D.   +4 more
europepmc   +1 more source

Identification of Natural and Artificial Modifications in DNA at the Nanometer Level

Journal of Raman Spectroscopy, EarlyView.
Short single‐ and double‐stranded DNA sequences with natural and artificial markers are examined at ambient conditions using TERS to identify and localize the labelled nucleobases. The differences between single‐ and double‐stranded DNA should provide clear experimental evidence of the extreme surface sensitivity of TERS.
Tanja Deckert‐Gaudig, Prabha Singh, Miklos Veres, Roman Holomb, Volker Deckert   +4 more
wiley   +1 more source

Combining single-molecule and structural studies reveals protein and DNA conformations and assemblies that govern DNA mismatch repair. [PDF]

Curr Opin Struct Biol
Erie DA, Weninger KR.
europepmc   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

DNA mismatch repair deficiency in conjunctival melanoma. [PDF]

Eye (Lond)
Rodriguez A, Moser J, Ramasubramanian A.
europepmc   +1 more source

Topological Photonic Devices and Circuits at Terahertz Frequencies

Laser &Photonics Reviews, EarlyView.
This review examines how 3D topological insulators and emerging topological photonic phases enable robust, low‐loss and defect‐immune terahertz devices. Fundamental properties, device implementations and topological transport mechanisms are surveyed, revealing new opportunities for reconfigurable, high‐performance THz components and scalable ...
Samane Kalhor, Srabani Kar, Ranjan Singh, Kaveh Delfanazari   +3 more
wiley   +1 more source

The ubiquitin ligase UBR4 and the deubiquitylase USP5 modulate the stability of DNA mismatch repair protein MLH1. [PDF]

J Biol Chem
Mao C, Li S, Che J, Liu D, Mao X, Rao H.
europepmc   +1 more source