Results 191 to 200 of about 71,628 (244)

DNA Mismatch Repair Gene Mosaicism Is Rare in People With Mismatch Repair-Deficient Cancers. [PDF]

open access: yesGastroenterology
Walker R   +6 more
europepmc   +1 more source

Advances in Double‐Stranded DNA Targeting Technologies

open access: yesExploration, EarlyView.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen   +8 more
wiley   +1 more source

Pulicaria incisa Infusion Modulates the Gut Microbiota and Improves Locomotor Activity and Exploratory Behavior in Aging Mice

open access: yesFood Frontiers, EarlyView.
‐Pi infusion significantly improved locomotor activity and exploratory behavior in aging mice; its bioactive compounds may have direct effects on behavior, which may be accompanied by a putative indirect effect involving the gut microbiota. ‐Pi infusion consumption restored commensal Bacilli levels and caused a significant decrease in Clostridia levels
Yulia Kroupitski   +7 more
wiley   +1 more source

Clinicopathological significance of deficient DNA mismatch repair and MLH1 promoter methylation in gastric adenosquamous carcinoma. [PDF]

open access: yesVirchows Arch
Gu Y   +15 more
europepmc   +1 more source

Genomic and Immune Correlates of EZH2 Expression and Activity in Olfactory Neuroblastoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Purpose Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy with limited therapeutic options in the recurrent/metastatic setting; little is known regarding its responsiveness to immunotherapy. Inhibition of enhancer of zeste homolog 2 (EZH2) has been shown to improve T‐cell‐mediated killing and susceptibility to immune checkpoint ...
Elisabetta Xue   +12 more
wiley   +1 more source

Spin‐Crossover Modulated Luminescence in Materials and Molecular Complexes

open access: yesHelvetica Chimica Acta, EarlyView.
The synergistic coupling of spin‐crossover and luminescent properties holds great promise for the development of multifunctional and stimuli‐responsive molecular materials. This contribution provides a comprehensive overview of the field, surveying the possible coupling mechanisms, the various synthetic strategies and their potential applicability, as ...
Charlotte Egger, Claude Piguet
wiley   +1 more source

DNA mismatch repair (MMR) genes expression in lung cancer and its correlation with different clinicopathologic parameters. [PDF]

open access: yesSci Rep
Farrag MS   +7 more
europepmc   +1 more source

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